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Chemical Compound Review

AGN-PC-00KHL0     4-amino-N-[5-amino-2-[4- amino-3,5...

Synonyms: AG-K-28440, SureCN13260939, NSC-177001, CTK8F7707, AR-1G0924, ...
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Disease relevance of amikacin


Psychiatry related information on amikacin


High impact information on amikacin


Chemical compound and disease context of amikacin


Biological context of amikacin


Anatomical context of amikacin


Associations of amikacin with other chemical compounds


Gene context of amikacin


Analytical, diagnostic and therapeutic context of amikacin


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  3. Improving treatment of chemotherapy-induced neutropenic fever by administration of colony-stimulating factors. Mayordomo, J.I., Rivera, F., Díaz-Puente, M.T., Lianes, P., Colomer, R., López-Brea, M., López, E., Paz-Ares, L., Hitt, R., García-Ribas, I. J. Natl. Cancer Inst. (1995) [Pubmed]
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  13. Treatment of disseminated Mycobacterium avium complex infection in AIDS with amikacin, ethambutol, rifampin, and ciprofloxacin. California Collaborative Treatment Group. Chiu, J., Nussbaum, J., Bozzette, S., Tilles, J.G., Young, L.S., Leedom, J., Heseltine, P.N., McCutchan, J.A. Ann. Intern. Med. (1990) [Pubmed]
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  16. Spectinomycin kinase from Legionella pneumophila. Characterization of substrate specificity and identification of catalytically important residues. Thompson, P.R., Hughes, D.W., Cianciotto, N.P., Wright, G.D. J. Biol. Chem. (1998) [Pubmed]
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  19. Progressive increase in antibiotic resistance of gram-negative bacterial isolates. Walter Reed Hospital, 1976 to 1980: specific analysis of gentamicin, tobramycin, and amikacin resistance. Cross, A.S., Opal, S., Kopecko, D.J. Arch. Intern. Med. (1983) [Pubmed]
  20. Mycobacterium fortuitum pulmonary infection associated with an antigen-selective defect in cellular immunity. Metcalf, J.F., John, J.F., Wilson, G.B., Fudenberg, H.H., Harley, R.A. Am. J. Med. (1981) [Pubmed]
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  22. Complementary roles of neurotrophin 3 and a N-methyl-D-aspartate antagonist in the protection of noise and aminoglycoside-induced ototoxicity. Duan, M., Agerman, K., Ernfors, P., Canlon, B. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
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  25. Gentamicin/amikacin-resistant gram-negative bacilli at Detroit General Hospital, 1975-1976. Jauregui, L., Cushing, R.D., Lerner, A.M. Am. J. Med. (1977) [Pubmed]
  26. Multicenter, randomized trial of ciprofloxacin plus azlocillin versus ceftazidime plus amikacin for empiric treatment of febrile neutropenic patients. Flaherty, J.P., Waitley, D., Edlin, B., George, D., Arnow, P., O'Keefe, P., Weinstein, R.A. Am. J. Med. (1989) [Pubmed]
  27. Prospective study of amikacin versus netilmicin in the treatment of severe infection in hospitalized patients. Noone, M., Pomeroy, L., Sage, R., Noone, P. Am. J. Med. (1989) [Pubmed]
  28. Empiric therapy for infections in granulocytopenic cancer patients: continuous infusion of amikacin plus cephalothin. Feld, R., Tuffnell, P.G., Curtis, J.E., Messner, H.A., Hasselback, R. Arch. Intern. Med. (1979) [Pubmed]
  29. Aminoglycoside dosing in renal transplant patients. Comparison of nomogram and individualized pharmacokinetic methods in patients with shifting renal function. Tofte, R.W., Canafax, D.M., Simmons, R.L., Peterson, P.K. Ann. Surg. (1982) [Pubmed]
  30. The Cpx proteins of Escherichia coli K-12: evidence that cpxA, ecfB, ssd, and eup mutations all identify the same gene. Rainwater, S., Silverman, P.M. J. Bacteriol. (1990) [Pubmed]
  31. Isolation and characterization of mutants of Escherichia coli K12 resistant to the new aminoglycoside antibiotic, amikacin. Hull, R., Klinger, J.D., Moody, E.E. J. Gen. Microbiol. (1976) [Pubmed]
  32. Nephrotoxicants induce endothelin release and signaling in renal proximal tubules: effect on drug efflux. Terlouw, S.A., Masereeuw, R., Russel, F.G., Miller, D.S. Mol. Pharmacol. (2001) [Pubmed]
  33. Changes in MAP2 and tyrosinated alpha-tubulin expression in cochlear inner hair cells after amikacin treatment in the rat. Ladrech, S., Lenoir, M. J. Comp. Neurol. (2002) [Pubmed]
  34. Amikacin in the treatment of gram-negative pneumonia. Trenholme, G.M., McKellar, P.P., Rivera, N., Levin, S. Am. J. Med. (1977) [Pubmed]
  35. Upper and lower urinary tract infections: amikacin's role in managing surgical complications. Childs, S.J. Am. J. Med. (1986) [Pubmed]
  36. A phase II/III trial of antimicrobial therapy with or without amikacin in the treatment of disseminated Mycobacterium avium infection in HIV-infected individuals. AIDS Clinical Trials Group Protocol 135 Study Team. Parenti, D.M., Williams, P.L., Hafner, R., Jacobs, M.R., Hojczyk, P., Hooton, T.M., Barber, T.W., Simpson, G., van der Horst, C., Currier, J., Powderly, W.G., Limjoco, M., Ellner, J.J. AIDS (1998) [Pubmed]
  37. Amikacin concentrations in serum following intraoperative irrigation of the pleura and peritoneum. Van Way, C.W., Hasse, G. Ann. Surg. (1985) [Pubmed]
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