The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Myrtaceae


High impact information on Myrtaceae

  • (Myrtaceae) canopy trees at both ends of a substrate age gradient in the Hawaiian Islands pointed to differential patterns of adjustment to both nutrient limitation and removal of this limitation by long-term (8-14 years) nitrogen (N), phosphorus (P) and N + P fertilizations [3].
  • The essential oil obtained from the leaves of Psidium guyanensis Pers. (Myrtaceae) was studied against lethal seizures induced by intraperitoneal injection of pentylenetetrazole (80 mg/kg), picroptoxin (6 mg/kg), and strychnine (2 mg/kg) in mice [4].
  • Eugenol is a major component of essential oil isolated from the Eugenia caryophyllata (Myrtaceae), which has been widely used as a herbal drug [5].
  • Citridiol is an extract of the leaves of Corymbia citriodora (Myrtaceae), the lemon eucalyptus, and mostly consists of p-menthane-3,8-diol isomers [6].
  • In this study, the methanolic extract of the cortex of Eugenia caryophyllata Thunberg (Myrtaceae) was found to potently inhibit the prostaglandin E(2) production in lipopolysaccharide (LPS)-activated mouse macrophage RAW264.7 cells (98.3% inhibition at the test concentration of 10 microg/ml) [7].

Anatomical context of Myrtaceae

  • The crude extract of Calythropsis aurea (Myrtaceae) produced a pattern of differential cytotoxicity in the NCI 60 cell line assay which was similar to those of known tubulin-interactive compounds [8].

Associations of Myrtaceae with chemical compounds

  • The anti-inflammatory activity of abietic acid, a diterpene isolated from Pimenta racemosa var. grissea (Myrtaceae), was evaluated in-vivo and in-vitro [9].
  • METHODS: Nineteen collections of Myrtaceae plant extracts were screened for xanthine oxidase inhibition [10].
  • Streptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15%, w/v) as a substitute for water [11].
  • The unique occurrence of the flavone aglycone tricetin in Myrtaceae pollen [12].
  • (Myrtaceae) dry leaves extracts (water) on Oneridia volxemi hoppers (fifth-instar) feeding on cereals leaves (Triticum durum) under laboratory conditions [13].

Gene context of Myrtaceae

  • Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): structures of myrciacitrins I and II and myrciaphenones A and B [14].
  • The broad-leaved paper bark tree Melaleuca quinquenervia (Cav) (Myrtaceae) was introduced into Florida (USA) early in this century it has proliferated to such an extent that urgent measures are now required to control it [15].
  • (Myrtaceae) leaves as well as the volatile oil (Myrtii Oleum; MO) obtained from the leaves are used to lower the blood glucose level in type-2 diabetic patients in Turkish folk medicine [16].
  • During a screening of medicinal plants for inhibition of protein tyrosine phosphatase1B (PTP1B), an extract from Psidium guajava (Myrtaceae) leaves exhibited significant inhibitory effect on PTP1B [17].

Analytical, diagnostic and therapeutic context of Myrtaceae

  • Twenty-one Myrtaceae collections belonging to 10 species, 5 of which are used in Chilean folk medicine, were assayed for inhibitory activity towards the enzyme xanthine oxidase [18].


  1. Effect of Syzygium aromaticum extract on immediate hypersensitivity in rats. Kim, H.M., Lee, E.H., Hong, S.H., Song, H.J., Shin, M.K., Kim, S.H., Shin, T.Y. Journal of ethnopharmacology. (1998) [Pubmed]
  2. An extract of Syzygium aromaticum represses genes encoding hepatic gluconeogenic enzymes. Prasad, R.C., Herzog, B., Boone, B., Sims, L., Waltner-Law, M. Journal of ethnopharmacology. (2005) [Pubmed]
  3. Morphological and physiological adjustment to N and P fertilization in nutrient-limited Metrosideros polymorpha canopy trees in Hawaii. Cordell, S., Goldstein, G., Meinzer, F.C., Vitousek, P.M. Tree Physiol. (2001) [Pubmed]
  4. The leaf essential oil of Psidium guyanensis offers protection against pentylenetetrazole-induced seizures. Santos, F.A., Rao, V.S., Silveira, E.R. Planta Med. (1997) [Pubmed]
  5. Eugenol isolated from the essential oil of Eugenia caryophyllata induces a reactive oxygen species-mediated apoptosis in HL-60 human promyelocytic leukemia cells. Yoo, C.B., Han, K.T., Cho, K.S., Ha, J., Park, H.J., Nam, J.H., Kil, U.H., Lee, K.T. Cancer Lett. (2005) [Pubmed]
  6. Laboratory and field tests of the effectiveness of the lemon-eucalyptus extract, Citridiol, as a repellent against land leeches of the genus Haemadipsa (Haemadipsidae). Kirton, L.G. Ann. Trop. Med. Parasitol. (2005) [Pubmed]
  7. Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells. Kim, S.S., Oh, O.J., Min, H.Y., Park, E.J., Kim, Y., Park, H.J., Nam Han, Y., Lee, S.K. Life Sci. (2003) [Pubmed]
  8. Two new cytotoxic chalcones from Calythropsis aurea. Beutler, J.A., Cardellina, J.H., Gray, G.N., Prather, T.R., Shoemaker, R.H., Boyd, M.R., Lin, C.M., Hamel, E., Cragg, G.M. J. Nat. Prod. (1993) [Pubmed]
  9. Anti-inflammatory activity of abietic acid, a diterpene isolated from Pimenta racemosa var. grissea. Fernández, M.A., Tornos, M.P., García, M.D., de las Heras, B., Villar, A.M., Sáenz, M.T. J. Pharm. Pharmacol. (2001) [Pubmed]
  10. Inhibition of xanthine oxidase by Puerto Rican plant extracts. Guerrero, R.O., Guzman, A.L. Puerto Rico health sciences journal. (1998) [Pubmed]
  11. Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes. Pepato, M.T., Folgado, V.B., Kettelhut, I.C., Brunetti, I.L. Braz. J. Med. Biol. Res. (2001) [Pubmed]
  12. The unique occurrence of the flavone aglycone tricetin in Myrtaceae pollen. Campos, M.G., Webby, R.F., Markham, K.R. Z. Naturforsch., C, J. Biosci. (2002) [Pubmed]
  13. Laboratory evaluation of Melia azedarach L. and Eucalyptus globulus Labill. Extracts in order to control Ocneridia volxemi Bolivar (Orthoptera, Pamphaginae) hoppers. Bounechada, M., Doumandji, S.E., Laouer, H. Communications in agricultural and applied biological sciences. (2004) [Pubmed]
  14. Antidiabetic principles of natural medicines. II. Aldose reductase and alpha-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): structures of myrciacitrins I and II and myrciaphenones A and B. Yoshikawa, M., Shimada, H., Nishida, N., Li, Y., Toguchida, I., Yamahara, J., Matsuda, H. Chem. Pharm. Bull. (1998) [Pubmed]
  15. Isolation and identification of the toxic peptides from Lophyrotoma zonalis (Pergidae) sawfly larvae. Oelrichs, P.B., MacLeod, J.K., Seawright, A.A., Grace, P.B. Toxicon (2001) [Pubmed]
  16. Hypoglycaemic effects of myrtle oil in normal and alloxan-diabetic rabbits. Sepici, A., Gürbüz, I., Cevik, C., Yesilada, E. Journal of ethnopharmacology. (2004) [Pubmed]
  17. Antidiabetic effects of extracts from Psidium guajava. Oh, W.K., Lee, C.H., Lee, M.S., Bae, E.Y., Sohn, C.B., Oh, H., Kim, B.Y., Ahn, J.S. Journal of ethnopharmacology. (2005) [Pubmed]
  18. Xanthine oxidase inhibitory activity of Chilean Myrtaceae. Theoduloz, C., Pacheco, P., Schmeda-Hirschmann, G. Journal of ethnopharmacology. (1991) [Pubmed]
WikiGenes - Universities