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Disease relevance of Cymbopogon

  • The 10 compounds most active against E. coli (60 min BA(50) range in clear juice, 0.018-0.093%) were carvacrol, oregano oil, geraniol, eugenol, cinnamon leaf oil, citral, clove bud oil, lemongrass oil, cinnamon bark oil, and lemon oil [1].

High impact information on Cymbopogon


Biological context of Cymbopogon


Associations of Cymbopogon with chemical compounds

  • To test the hypothesis that non-sterol mevalonate pathway end products lower serum cholesterol levels, we asked 22 hypercholesterolemic subjects (315 +/- 9 mg cholesterol/dl) to take a daily capsule containing 140 mg of lemongrass oil, an essential oil rich in geraniol and citral [11].
  • Impact of lemongrass oil, an essential oil, on serum cholesterol [11].
  • An analytical method for proximadiol, the active principle of Cymbopogon proximus [12].
  • Mutagenicity of AFB1, Trp-P-1, Trp-P-2, Glu-P-1, Glu-P-2, IQ, MNNG and AF-2, was inhibited by the extract of lemon grass in a dose-dependent manner, but no effect was found on the mutagenic activity of benzo[a]pyrene [5].
  • Beta-Myrcene (MYR) is an acyclic monoterpene found in the essential oils of a variety of useful plants such as lemongrass (Cymbopogon citratus), hop, verbena, bay and others [13].

Gene context of Cymbopogon

  • The effect of cinnamon, clove, oregano, palmarose and lemongrass oils on growth and FB1 production by three different isolates of F. proliferatum in irradiated maize grain at 0.995 and 0.950 aw and at 20 and 30 degrees C was evaluated [14].
  • Mitotic effects of the aqueous leaf extract of Cymbopogon citratus in Allium cepa root tips [15].

Analytical, diagnostic and therapeutic context of Cymbopogon


  1. Antibacterial activities of plant essential oils and their components against Escherichia coli O157:H7 and Salmonella enterica in apple juice. Friedman, M., Henika, P.R., Levin, C.E., Mandrell, R.E. J. Agric. Food Chem. (2004) [Pubmed]
  2. Inhibitory effects of lemon grass (Cymbopogon citratus Stapf) on formation of azoxymethane-induced DNA adducts and aberrant crypt foci in the rat colon. Suaeyun, R., Kinouchi, T., Arimochi, H., Vinitketkumnuen, U., Ohnishi, Y. Carcinogenesis (1997) [Pubmed]
  3. A phase II detoxification enzyme inducer from lemongrass: identification of citral and involvement of electrophilic reaction in the enzyme induction. Nakamura, Y., Miyamoto, M., Murakami, A., Ohigashi, H., Osawa, T., Uchida, K. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  4. Antimicrobial activity of essential oils against Helicobacter pylori. Ohno, T., Kita, M., Yamaoka, Y., Imamura, S., Yamamoto, T., Mitsufuji, S., Kodama, T., Kashima, K., Imanishi, J. Helicobacter (2003) [Pubmed]
  5. Antimutagenicity of lemon grass (Cymbopogon citratus Stapf) to various known mutagens in salmonella mutation assay. Vinitketkumnuen, U., Puatanachokchai, R., Kongtawelert, P., Lertprasertsuke, N., Matsushima, T. Mutat. Res. (1994) [Pubmed]
  6. Biotransformation of geranyl acetate to geraniol during palmarosa (Cymbopogon martinii, Roxb. wats. var. motia) inflorescence development. Dubey, V.S., Luthra, R. Phytochemistry (2001) [Pubmed]
  7. Free radical scavengers and antioxidants from Lemongrass (Cymbopogon citratus (DC.) Stapf.). Cheel, J., Theoduloz, C., Rodríguez, J., Schmeda-Hirschmann, G. J. Agric. Food Chem. (2005) [Pubmed]
  8. Mevalonate phosphorylation in lemon grass leaves. Lalitha, R., Ramasarma, T. Indian J. Biochem. Biophys. (1986) [Pubmed]
  9. Sucrose mobilization in relation to essential oil biogenesis during palmarosa (Cymbopogon martinii Roxb. Wats. var. motia) inflorescence development. Dubey, V.S., Bhalla, R., Luthra, R. J. Biosci. (2003) [Pubmed]
  10. Response of Java citronella (Cymbopogon winterianus Jowitt) to toxic heavy metal cadmium. Boruah, H.P., Handique, A.K., Borah, G.C. Indian J. Exp. Biol. (2000) [Pubmed]
  11. Impact of lemongrass oil, an essential oil, on serum cholesterol. Elson, C.E., Underbakke, G.L., Hanson, P., Shrago, E., Wainberg, R.H., Qureshi, A.A. Lipids (1989) [Pubmed]
  12. An analytical method for proximadiol, the active principle of Cymbopogon proximus. Radwan, A.S. Planta Med. (1975) [Pubmed]
  13. Induction of liver monooxygenases by beta-myrcene. De-Oliveira, A.C., Ribeiro-Pinto, L.F., Otto, S.S., Gonçalves, A., Paumgartten, F.J. Toxicology (1997) [Pubmed]
  14. Inhibitory effect of cinnamon, clove, lemongrass, oregano and palmarose essential oils on growth and fumonisin B1 production by Fusarium proliferatum in maize grain. Velluti, A., Sanchis, V., Ramos, A.J., Egido, J., Marín, S. Int. J. Food Microbiol. (2003) [Pubmed]
  15. Mitotic effects of the aqueous leaf extract of Cymbopogon citratus in Allium cepa root tips. Williams, G.O., Omoh, L.E. Cytobios (1996) [Pubmed]
  16. Fungicidal and anti-aflatoxigenic effects of the essential oil of Cymbopogon citratus (DC.) Stapf. (lemongrass) against Aspergillus flavus Link. isolated from stored rice. Paranagama, P.A., Abeysekera, K.H., Abeywickrama, K., Nugaliyadde, L. Lett. Appl. Microbiol. (2003) [Pubmed]
  17. The quantification of citral in lemongrass and lemon oils by near-infrared spectroscopy. Wilson, N.D., Ivanova, M.S., Watt, R.A., Moffat, A.C. J. Pharm. Pharmacol. (2002) [Pubmed]
  18. Absence of genotoxic activity of beta-myrcene in the in vivo cytogenetic bone marrow assay. Zamith, H.P., Vidal, M.N., Speit, G., Paumgartten, F.J. Braz. J. Med. Biol. Res. (1993) [Pubmed]
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