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Chemical Compound Review

MYRCENE     7-methyl-3-methylidene-octa- 1,6-diene

Synonyms: b-Myrcene, beta-Myrcene, MYRCENE, TECH, CHEMBL455491, CPD-4888, ...
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Disease relevance of LS-678


High impact information on LS-678


Biological context of LS-678


Anatomical context of LS-678


Associations of LS-678 with other chemical compounds


Gene context of LS-678

  • The main monoterpene constituents of each oil, beta-myrcene (in PR) and limonene (in CB), were tested in the LPS-induced pleurisy model and assayed also for immunoregulatory activity by measurement of the inhibition of NO and production of the cytokines, gamma-interferon and IL-4 [13].

Analytical, diagnostic and therapeutic context of LS-678

  • The chemical structures of the active components were determined on the basis of mass spectrometry linked to gas chromatography, indicating E-beta-ocimene and beta-myrcene as stimulants for neurone type 1, E,E-alpha-farnesene for neurone type 2 and homo-farnesene for neurone type 3 [14].


  1. Identification and sequencing of beta-myrcene catabolism genes from Pseudomonas sp. strain M1. Iurescia, S., Marconi, A.M., Tofani, D., Gambacorta, A., Paternò, A., Devirgiliis, C., van der Werf, M.J., Zennaro, E. Appl. Environ. Microbiol. (1999) [Pubmed]
  2. Peri- and postnatal developmental toxicity of beta-myrcene in the rat. Delgado, I.F., Nogueira, A.C., Souza, C.A., Costa, A.M., Figueiredo, L.H., Mattos, A.P., Chahoud, I., Paumgartten, F.J. Food Chem. Toxicol. (1993) [Pubmed]
  3. Study on embryo-foetotoxicity of beta-myrcene in the rat. Delgado, I.F., Carvalho, R.R., Nogueira, A.C., Mattos, A.P., Figueiredo, L.H., Oliveira, S.H., Chahoud, I., Paumgartten, F.J. Food Chem. Toxicol. (1993) [Pubmed]
  4. Influence of beta-myrcene on sister-chromatid exchanges induced by mutagens in V79 and HTC cells. Röscheisen, C., Zamith, H., Paumgartten, F.J., Speit, G. Mutat. Res. (1991) [Pubmed]
  5. Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense. Treyvaud Amiguet, V., Petit, P., Ta, C.A., Nuñez, R., Sánchez-Vindas, P., Alvarez, L.P., Smith, M.L., Arnason, J.T., Durst, T. J. Nat. Prod. (2006) [Pubmed]
  6. Functional expression of a bark beetle cytochrome P450 that hydroxylates myrcene to ipsdienol. Sandstrom, P., Welch, W.H., Blomquist, G.J., Tittiger, C. Insect Biochem. Mol. Biol. (2006) [Pubmed]
  7. Absence of genotoxic activity of beta-myrcene in the in vivo cytogenetic bone marrow assay. Zamith, H.P., Vidal, M.N., Speit, G., Paumgartten, F.J. Braz. J. Med. Biol. Res. (1993) [Pubmed]
  8. Neurobehavioral study of the effect of beta-myrcene on rodents. da-Silva, V.A., de-Freitas, J.C., Mattos, A.P., Paiva-Gouvea, W., Presgrave, O.A., Fingola, F.F., Menezes, M.A., Paumgartten, F.J. Braz. J. Med. Biol. Res. (1991) [Pubmed]
  9. Comparison of extraction methods for marker compounds in the essential oil of lemon grass by GC. Schaneberg, B.T., Khan, I.A. J. Agric. Food Chem. (2002) [Pubmed]
  10. Metabolism of beta-myrcene in vivo and in vitro: its effects on rat-liver microsomal enzymes. Madyastha, K.M., Srivatsan, V. Xenobiotica (1987) [Pubmed]
  11. Anticonflict effects of lavender oil and identification of its active constituents. Umezu, T., Nagano, K., Ito, H., Kosakai, K., Sakaniwa, M., Morita, M. Pharmacol. Biochem. Behav. (2006) [Pubmed]
  12. Effects of four monoterpenoids on growth and reproduction of the German cockroach (Blattodea: Blattellidae). Karr, L.L., Coats, J.R. J. Econ. Entomol. (1992) [Pubmed]
  13. Evaluation of anti-inflammatory activity of essential oils from two Asteraceae species. Souza, M.C., Siani, A.C., Ramos, M.F., Menezes-de-Lima, O.J., Henriques, M.G. Die Pharmazie. (2003) [Pubmed]
  14. Selective receptor neurone responses to E-beta-ocimene, beta-myrcene, E,E-alpha-farnesene and homo-farnesene in the moth Heliothis virescens, identified by gas chromatography linked to electrophysiology. Røstelien, T., Borg-Karlson, A.K., Mustaparta, H. J. Comp. Physiol. A (2000) [Pubmed]
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