The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Volvox

  • While introns in the 5' untranslated region and between codons 41-42 and 121-122 are present in many organisms, the introns in positions 168 and 246-247 had only been found previously in actin genes from the nematode Onchocerca volvulus and the green alga Volvox carterii, respectively [1].

High impact information on Volvox

  • Sequence comparisons indicate that the self-assembling proteins that create the main parts of the complex Volvox ECM have evolved from a common ancestral gene [2].
  • The sex-inducing pheromone of Volvox carteri is a glycoprotein that triggers development of males and females at a concentration below 10(-16) M [3].
  • We have isolated a 1595-bp transposable element from the multicellular green alga Volvox carteri following its insertion into the nitrate reductase (nitA) locus [4].
  • The corresponding transgenic Volvox strain synthesized the sugar transporter in a functional state and was able to efficiently incorporate 14C from labeled glucose or glucosamine [5].
  • Response to the sexual pheromone and wounding in the green alga volvox: induction of an extracellular glycoprotein consisting almost exclusively of hydroxyproline [6].

Biological context of Volvox


Anatomical context of Volvox

  • The structures of more than 10 ECM glycoproteins from a single species of Volvox are now known in molecular detail and are compared to other algal and plant cell wall/ECM glycoproteins [10].
  • However, Volvox microsomes liberated most of the glucose indicating a specific glucosidase in the membranes of the alga [11].

Associations of Volvox with chemical compounds


Gene context of Volvox

  • Two Volvox genomic clones each containing a pair of histone H3-H4 genes were sequenced [9].
  • The Volvox H3 gene structure combines the exon-intron organization of fungal H3 and vertebrate H3.3 genes with a termination signal typical for animal H3.1 genes [9].
  • The extracellular matrix (ECM) of Volvox contains insoluble fibrous layers that surround individual cells at a distance to form contiguous cellular compartments [8].
  • The Volvox HRGP is also found to be inducible by wounding [6].
  • The rhodopsin action spectrum suggests that the currents are induced by Volvox rhodopsin [17].


  1. Actin gene structure in two Artemia species, A. franciscana and A. parthenogenetica. Ortega, M.A., Díaz-Guerra, M., Sastre, L. J. Mol. Evol. (1996) [Pubmed]
  2. Differential targeting of closely related ECM glycoproteins: the pherophorin family from Volvox. Godl, K., Hallmann, A., Wenzl, S., Sumper, M. EMBO J. (1997) [Pubmed]
  3. How a sex pheromone might act at a concentration below 10(-16) M. Sumper, M., Berg, E., Wenzl, S., Godl, K. EMBO J. (1993) [Pubmed]
  4. Jordan, an active Volvox transposable element similar to higher plant transposons. Miller, S.M., Schmitt, R., Kirk, D.L. Plant Cell (1993) [Pubmed]
  5. The Chlorella hexose/H+ symporter is a useful selectable marker and biochemical reagent when expressed in Volvox. Hallmann, A., Sumper, M. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  6. Response to the sexual pheromone and wounding in the green alga volvox: induction of an extracellular glycoprotein consisting almost exclusively of hydroxyproline. Ender, F., Hallmann, A., Amon, P., Sumper, M. J. Biol. Chem. (1999) [Pubmed]
  7. A novel extensin that may organize extracellular matrix biogenesis in Volvox carteri. Ertl, H., Hallmann, A., Wenzl, S., Sumper, M. EMBO J. (1992) [Pubmed]
  8. The extracellular matrix of Volvox carteri: molecular structure of the cellular compartment. Ertl, H., Mengele, R., Wenzl, S., Engel, J., Sumper, M. J. Cell Biol. (1989) [Pubmed]
  9. Histone genes of Volvox carteri: DNA sequence and organization of two H3-H4 gene loci. Müller, K., Schmitt, R. Nucleic Acids Res. (1988) [Pubmed]
  10. Biochemistry of the extracellular matrix of Volvox. Sumper, M., Hallmann, A. Int. Rev. Cytol. (1998) [Pubmed]
  11. Evidence for an incomplete dolichyl-phosphate pathway of lipoglycan formation in Volvox carteri f. nagariensis. Müller, T., Bause, E., Jaenicke, L. Eur. J. Biochem. (1984) [Pubmed]
  12. Evidence for autocatalytic cross-linking of hydroxyproline-rich glycoproteins during extracellular matrix assembly in Volvox. Ender, F., Godl, K., Wenzl, S., Sumper, M. Plant Cell (2002) [Pubmed]
  13. Prolyl 4-hydroxylase from Volvox carteri. A low-Mr enzyme antigenically related to the alpha subunit of the vertebrate enzyme. Kaska, D.D., Myllylä, R., Günzler, V., Gibor, A., Kivirikko, K.I. Biochem. J. (1988) [Pubmed]
  14. Inhibition of phosphate uptake by fluphenazine, a calmodulin inhibitor. Analysis of Volvox wild-type and fluphenazine-resistant mutant strains. Kurn, N. FEBS Lett. (1982) [Pubmed]
  15. Cyclic AMP as an intraspheroidal differentiation signal in Volvox carteri. Gilles, R., Moka, R., Gilles, C., Jaenicke, L. FEBS Lett. (1985) [Pubmed]
  16. Glycolipid formation in Volvox carteri f. nagariensis: effects of tunicamycin and showdomycin. Müller, T., Bause, E., Jaenicke, L. FEBS Lett. (1981) [Pubmed]
  17. Two light-activated conductances in the eye of the green alga Volvox carteri. Braun, F.J., Hegemann, P. Biophys. J. (1999) [Pubmed]
WikiGenes - Universities