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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Histiocytoma


High impact information on Histiocytoma


Anatomical context of Histiocytoma


Gene context of Histiocytoma

  • In conclusion, the GH may be involved in the development of different kinds of cutaneous neoplasms, and the intracellular localization of GHR may imply a functional significance, at least in the histiocytomas [11].
  • The gene coding for the cellular tumor antigen p53 is rearranged and overexpressed in a rat histiocytoma, AK-5 [7].
  • Rings, dicentrics, and telomeric association in histiocytomas [12].
  • Immunoperoxidase investigations for desmin demonstrated positivity in the angio-leiomyoma, whereas the histiocytoma remained negative [13].
  • One infant with a solitary lesion on the forehead was diagnosed as solitary, congenital, indeterminate cell histiocytoma because the histiocytic cells were S-100 protein positive, but meticulous ultrastructural studies did not detect Birbeck granules [14].


  1. Cervical/vaginal dysplasias of transgenic mice harbouring human papillomavirus type 16 E6-E7 genes. Sasagawa, T., Kondoh, G., Inoue, M., Yutsudo, M., Hakura, A. J. Gen. Virol. (1994) [Pubmed]
  2. Mammary gland tumor in transgenic mice expressing targeted beta-casein/HPV16E6 fusion gene. Hwang, D.Y., Chae, K.R., Shin, D.H., Jang, I.S., Hwang, J.H., Kim, Y.J., Cho, J.Y., Kim, B.J., Goo, J.S., Lim, C.J., Kim, C.K., Cho, Y.Y., Paik, S.G., Kim, Y.K., Cho, J.S. Int. J. Oncol. (2000) [Pubmed]
  3. Malignant mesothelioma induced by asbestos and zeolite in the mouse peritoneal cavity. Suzuki, Y., Kohyama, N. Environmental research. (1984) [Pubmed]
  4. mu-chain disease in a case of chronic lymphocytic leukaemia and malignant histiocytoma. I. Clinical aspects. Jonsson, V., Videbek, A., Axelsen, N.H., Harboe, M. Scandinavian journal of haematology. (1976) [Pubmed]
  5. Pediatric spinal tumors. Schick, U., Marquardt, G. Pediatric neurosurgery. (2001) [Pubmed]
  6. Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates. Bhaumik, S., Anjum, R., Rangaraj, N., Pardhasaradhi, B.V., Khar, A. FEBS Lett. (1999) [Pubmed]
  7. Rearrangement and overexpression of the gene coding for tumor antigen p53 in a rat histiocytoma AK-5. Deshpande, G., Kumari, A.L., Khar, A. FEBS Lett. (1990) [Pubmed]
  8. Correlation of in vitro and in vivo effects of interferon-gamma with the spontaneous regression of a rat histiocytoma. Kausalya, S., Varalakshmi, C., Khar, A. J. Interferon Cytokine Res. (1995) [Pubmed]
  9. Expression of insulin-like growth factor 1 in sarcomas. Roholl, P.J., Skottner, A., Prinsen, I., Lips, C.J., Den Otter, W., Van Unnik, J.A. Histopathology (1990) [Pubmed]
  10. Immunohistochemical expression of p27 and p21 in canine cutaneous mast cell tumors and histiocytomas. Wu, H., Hayashi, T., Inoue, M. Vet. Pathol. (2004) [Pubmed]
  11. Expression of growth hormone receptor in benign and malignant cutaneous proliferative entities. Ginarte, M., García-Caballero, T., Fernández-Redondo, V., Beiras, A., Toribio, J. J. Cutan. Pathol. (2000) [Pubmed]
  12. Rings, dicentrics, and telomeric association in histiocytomas. Mandahl, N., Heim, S., Arheden, K., Rydholm, A., Willén, H., Mitelman, F. Cancer Genet. Cytogenet. (1988) [Pubmed]
  13. Angioleiomyoma within a histiocytoma. Requena, L., Ortiz, S., Sánchez, M., Yus, E.S. J. Cutan. Pathol. (1990) [Pubmed]
  14. Histiocytic disorders with spontaneous regression in infancy. Jang, K.A., Ahn, S.J., Choi, J.H., Sung, K.J., Moon, K.C., Koh, J.K. Pediatric dermatology. (2000) [Pubmed]
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