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MeSH Review

Bird Fancier's Lung

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Disease relevance of Bird Fancier's Lung


High impact information on Bird Fancier's Lung


Chemical compound and disease context of Bird Fancier's Lung

  • It is unknown to what extent pigeon-breeder's lung caused by nondomestic birds remains undetected and misdiagnosed as difficult or steroid-resistant asthma [7].
  • The present study has shown that: (1) All patients with bird fancier's lung (BFL) demonstrated either a restrictive pattern or a reduced diffusing capacity for carbon monoxide (DLco), or both; one BFL patient showed deterioration in %VC and %DLco after avoidance of direct exposure [8].
  • Four patients with pigeon breeder's lung and positive lymphocyte transformation tests to pigeon antigen were given 250 mg hydrocortisone intravenously, after which the test was repeated at 6, 24, and 30 hr [9].

Anatomical context of Bird Fancier's Lung

  • Sera from all symptomatics with pigeon breeders' lung and many non-symptomatic pigeon breeders react specifically with the pigeon antigens and in particular pigeon intestinal secretions and isolated pigeon intestinal mucin and IgA [6].

Gene context of Bird Fancier's Lung


Analytical, diagnostic and therapeutic context of Bird Fancier's Lung

  • To assess its value as a screen for avian antibodies, indirect immunofluorescence against avian intestinal tissue has been to test sera from thirty-nine patients with documented bird-fancier's lung disease, thirty-eight asymptomatic bird-fanciers and 257 controls without known avian contact [11].


  1. Chronic hypersensitivity pneumonitis in Japan: a nationwide epidemiologic survey. Yoshizawa, Y., Ohtani, Y., Hayakawa, H., Sato, A., Suga, M., Ando, M. J. Allergy Clin. Immunol. (1999) [Pubmed]
  2. Immune responsiveness to inhaled antigens: local antibody production in the respiratory tract in health and lung diseases. Yoshizawa, Y., Ohtani, Y., Inoue, T., Miyake, S., Ikeda, A., Tanba, M., Kurup, V.P. Clin. Exp. Immunol. (1995) [Pubmed]
  3. Bird-fancier's lung and jejunal villous atrophy. Berrill, W.T., Fitzpatrick, P.F., Macleod, W.M., Eade, O.E., Hyde, I., Wright, R. Lancet (1975) [Pubmed]
  4. Tumor necrosis factor-alpha -308 promoter gene polymorphism and increased tumor necrosis factor serum bioactivity in farmer's lung patients. Schaaf, B.M., Seitzer, U., Pravica, V., Aries, S.P., Zabel, P. Am. J. Respir. Crit. Care Med. (2001) [Pubmed]
  5. Analysis of KL-6 and SP-D as disease markers in bird fancier's lung. Janssen, R., Grutters, J.C., Sato, H., van Velzen-Blad, H., Zanen, P., Kohno, N., Welsh, K.I., du Bois, R.M., van den Bosch, J.M. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG / World Association of Sarcoidosis and Other Granulomatous Disorders. (2005) [Pubmed]
  6. Pigeon breeders' lung; IgG subclasses to pigeon intestinal mucin and IgA antigens. Todd, A., Coan, R., Allen, A. Clin. Exp. Immunol. (1993) [Pubmed]
  7. A family with extrinsic allergic alveolitis caused by wild city pigeons: A case report. du Marchie Sarvaas, G.J., Merkus, P.J., de Jongste, J.C. Pediatrics (2000) [Pubmed]
  8. Sequential evaluation of clinical and immunological findings in hypersensitivity pneumonitis: serial subclass distribution of antibodies. Yoshizawa, Y., Miyashita, Y., Inoue, T., Sumi, Y., Miyazaki, Y., Sato, T., Ohtsuka, M. Clin. Immunol. Immunopathol. (1994) [Pubmed]
  9. Effect of corticosteroid on lymphocyte responsiveness in pigeon breeder's lung. Toogood, J.H., Khan, R.H., Baskerville, J.C., Jennings, B.H. Clin. Allergy (1980) [Pubmed]
  10. Pigeon breeders' lung: pigeon intestinal mucin, an antigen distinct from pigeon IgA. Todd, A., Coan, R.M., Allen, A. Clin. Exp. Immunol. (1991) [Pubmed]
  11. Immunofluorescent antibodies in patients with bird-fancier's lung. Eade, O.E., Hodges, J.R., Berrill, W.T., Lang, C., Lloyd, R.S., Wright, R. Clin. Exp. Immunol. (1978) [Pubmed]
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