Disease relevance of Tissue Expansion

• The reconstructive surgeon should be alert to the possibility of this phenomenon occurring as a result of tissue expansion in the patient with severe osteoporosis, peripheral vascular disease, or chronic steroid use [1].
• Application of capsaicin into the saline pretreated TMJ region led to dose-dependent edema development and reflex jaw muscle activity; however, only 1% capsaicin solution resulted in significant tissue expansion and muscle activity when compared with the vehicle control [2].

High impact information on Tissue Expansion

• An alternate, though not mutually exclusive, model places OBP3 as a general inhibitor of tissue expansion with phyB and cry1, differentially modulating OBP3's role in this response [3].
• The activity of fructose 1,6-bisphosphatase appears to be merely keeping pace with general tissue expansion [4].
• The urokinase plasminogen activator (uPA)-dependent proteolytic cascade as well as ligand activation of the uPA receptor (uPAR) is critically involved in physiological as well as pathophysiological aspects of tissue expansion and remodelling [5].
• BACKGROUND: Immediate breast reconstruction techniques include tissue-expansion, latissimus dorsi flap with or without an implant, pedicled TRAM flap and free tissue-transfer [6].
• Tissue expansion using osmotically active hydrogel systems for direct closure of the donor defect of the radial forearm flap [7].

Associations of Tissue Expansion with chemical compounds

• Lidocaine to relieve pain with tissue expansion of the breast [8].
• After 1 month of tissue expansion, and IMZ implant was placed in the atrophic ridge on each side in such a way that its coronal 4 mm to 5 mm remained circumferentially exposed above the bone level [9].
• Abdominal tissue expansion aids in placement of the baclofen pump and other implantation devices [10].
• Epidermal mitotic activity during tissue expansion has been assessed in the guinea pig using tritiated thymidine and other confirmatory techniques [11].
• Accelerating tissue expansion by application of topical papaverine cream [12].

Gene context of Tissue Expansion

• Similar differences were found when patients were subgrouped by type of reconstruction (TRAM versus tissue expansion and implants), by laterality (unilateral versus bilateral), and by history of preoperative irradiation [13].
• The failure rate after tissue expansion (21 percent) was significantly higher than those observed with the TRAM (3 percent) and latissimus (9 percent) flaps [14].
• The effect of relaxin on tissue expansion [15].
• Vascular endothelial growth factor expression in expanded tissue: a possible mechanism of angiogenesis in tissue expansion [16].
• Tissue expansion is well-suited modification to overcome this limitation, but as applied to the midline forehead flap, it does not address the resulting vertical forehead scar [17].

Analytical, diagnostic and therapeutic context of Tissue Expansion

• This study shows that the rate of tissue expansion can be accelerated by topical application of papaverine cream, and the rate is better than the rate of tissue expansion induced by the special drug delivery system [12].

References