Disease relevance of Zoogloea

• The gram-positive Arthrobacter sp. strain 9G4D and gram-negative species P. pickettii and Zoogloea sp. WNJ8, when supplied with pyruvate as a carbon and energy source, were capable of superior growth in the fluid phase but formed only a low to moderate biofilm surface coverage [1].
• The NADPH-linked acetoacetyl-CoA reductase, (R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.36), from the bacterium Zoogloea ramigera, involved in the formation of D-3-hydroxybutyryl-CoA for poly(D-3-hydroxybutyrate) biosynthesis, has been purified from an over-producing Escherichia coli strain [2].
• Furthermore, acetoacetyl-CoA reductases (ARs) from both Ralstonia eutropha and Zoogloea ramigera, whose genes are significantly similar to fabG genes and play a physiological role in the biosynthesis of poly-beta-3-hydroxybutyrate, could also catalyze the asymmetric reduction of ECAA to ( S)-ECHB with >99% ee [3].

High impact information on Zoogloea

• Intracellular degradation of poly(3-hydroxybutyrate) granules of Zoogloea ramigera I-16-M [4].
• This failure is attributed to the inability demonstrated in this study of acetyldithio-CoA to thioacetylate the active site Cys89 of the Zoogloea ramigera thiolase [5].
• The biosynthetic thiolase, from Zoogloea ramigera, involved in generation of acetoacetyl-CoA for poly-beta-hydroxybutyrate synthesis, has been prepared pure in quantity for initial structural characterization of this homotetrameric enzyme [6].
• Biosynthetic thiolase from Zoogloea ramigera. II. Inactivation with haloacetyl CoA analogs [7].
• Fine structural analysis of the Zoogloea ramigera phbA-phbB locus encoding beta-ketothiolase and acetoacetyl-CoA reductase: nucleotide sequence of phbB [8].

Chemical compound and disease context of Zoogloea

• Exocellular polymer was isolated from zoogloeae of Zoogloea strains MP6 and 106 and from activated sludge flocs by blending samples with phosphate buffer and precipitation of solubilized polymer with cetyltrimethylammonium bromide [9].
• The chemotaxonomic data suggested that the rhodoquinone-lacking strains should be excluded from the genus Zoogloea [10].
• Nine Zoogloea strains including the type strain of Z. ramigera (IAM 12136 = ATCC 19544 = N.C. Dondero 106) and newly isolated strains were investigated for isoprenoid quinone composition and whole-cell fatty acid profiles [10].
• An extracellular polysaccharide produced by Zoogloea ramigera 115 [11].
• The oxygen and nitrate reduction kinetics of a nonflocculating strain of Zoogloea ramigera were determined [12].

Biological context of Zoogloea

• Bioaugmentation with Zoogloea resiniphila DhA-35, a DhA-degrading bacterium originally isolated from a pulp mill treatment system, restored the DhA removal by both the low- and high-pH-stressed lagoon biomass [13].

Gene context of Zoogloea

• In contrast with HMG-CoA synthase, C378G Zoogloea ramigera beta-ketothiolase, which also forms a (13)C NMR-observable covalent acetyl-enzyme species, exhibits no (18)O-induced shift [14].
• Purification and properties of beta-ketothiolase from Zoogloea ramigera [15].
• Purification and characterization of acetoacetyl-CoA synthetase from Zoogloea ramigera I-16-M [16].
• This mitochondrial thiolase is homologous with the mature portion of peroxisomal 3-oxoacyl-CoA thiolase and acetoacetyl-CoA thiolase [EC 2.3.1.9] of Zoogloea ramigera along the entire sequence [17].
• Fatty acyl-CoAs of various chain lengths dose-dependently inhibited acetoacetyl-CoA synthetase from rat liver, but much less effectively a similar enzyme from a bacterium, Zoogloea ramigera I-16-M [18].

References