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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Arteritis


Psychiatry related information on Arteritis


High impact information on Arteritis


Chemical compound and disease context of Arteritis

  • By changing to a daily regimen, the arteritis was controlled in most patients in group C. Adverse reactions to prednisone were noted frequently in groups A and B but rarely in group C [12].
  • CONCLUSIONS: Treatment with methotrexate plus corticosteroid is a safe alternative to corticosteroid therapy alone in patients with giant-cell arteritis and is more effective in controlling disease [11].
  • Conversely, arteritis significantly accelerated cholesterol-induced atherosclerosis [13].
  • The well recognized untoward effects are tractable save for the definite augmentation of carcinogenesis, a measurable risk that is regarded as acceptable in treating rheumatoid arthritis with azathioprine and rheumatoid arteritis with cyclophosphamide [14].
  • This case suggests that fludeoxyglucose F 18 PET contributes to the noninvasive diagnosis of giant cell arteritis, as well as to the evaluation of the extent of disease, response to therapy, and disease recurrence [15].

Biological context of Arteritis


Anatomical context of Arteritis


Gene context of Arteritis


Analytical, diagnostic and therapeutic context of Arteritis


  1. Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. Weck, K.E., Dal Canto, A.J., Gould, J.D., O'Guin, A.K., Roth, K.A., Saffitz, J.E., Speck, S.H., Virgin, H.W. Nat. Med. (1997) [Pubmed]
  2. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions. Sanderson, N., Factor, V., Nagy, P., Kopp, J., Kondaiah, P., Wakefield, L., Roberts, A.B., Sporn, M.B., Thorgeirsson, S.S. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  3. Circulating immune complexes in giant cell arteritis and polymyalgia rheumatica. Papaioannou, C.C., Gupta, R.C., Hunder, G.G., McDuffie, F.C. Arthritis Rheum. (1980) [Pubmed]
  4. Decorin is produced by capillary endothelial cells in inflammation-associated angiogenesis. Nelimarkka, L., Salminen, H., Kuopio, T., Nikkari, S., Ekfors, T., Laine, J., Pelliniemi, L., Järveläinen, H. Am. J. Pathol. (2001) [Pubmed]
  5. Giant cell arteritis associated with mononeuritis multiplex and complement-activating 19S IgM rheumatoid factor. Feigal, D.W., Robbins, D.L., Leek, J.C. Am. J. Med. (1985) [Pubmed]
  6. Cotton-wool spots. Brown, G.C., Brown, M.M., Hiller, T., Fischer, D., Benson, W.E., Magargal, L.E. Retina (Philadelphia, Pa.) (1985) [Pubmed]
  7. Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. Nicklin, M.J., Hughes, D.E., Barton, J.L., Ure, J.M., Duff, G.W. J. Exp. Med. (2000) [Pubmed]
  8. Steroid therapy for visual loss in patients with giant-cell arteritis. Hayreh, S.S. Lancet (2000) [Pubmed]
  9. Cerebral arteritis and oral methylphenidate. Trugman, J.M. Lancet (1988) [Pubmed]
  10. Allopurinol-associated arteritis. Bailey, R.R., Neale, T.J., Lynn, K.L. Lancet (1976) [Pubmed]
  11. Combined treatment of giant-cell arteritis with methotrexate and prednisone. a randomized, double-blind, placebo-controlled trial. Jover, J.A., Hernández-García, C., Morado, I.C., Vargas, E., Bañares, A., Fernández-Gutiérrez, B. Ann. Intern. Med. (2001) [Pubmed]
  12. Daily and alternate-day corticosteroid regimens in treatment of giant cell arteritis: comparison in a prospective study. Hunder, G.G., Sheps, S.G., Allen, G.L., Joyce, J.W. Ann. Intern. Med. (1975) [Pubmed]
  13. Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model. Ludewig, B., Freigang, S., Jäggi, M., Kurrer, M.O., Pei, Y.C., Vlk, L., Odermatt, B., Zinkernagel, R.M., Hengartner, H. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  14. Azathioprine and cyclophosphamide as slow-acting drugs for rheumatoid arthritis. Decker, J.L. Am. J. Med. (1983) [Pubmed]
  15. Fludeoxyglucose positron emission tomography in the diagnosis of giant cell arteritis. Turlakow, A., Yeung, H.W., Pui, J., Macapinlac, H., Liebovitz, E., Rusch, V., Goy, A., Larson, S.M. Arch. Intern. Med. (2001) [Pubmed]
  16. An autosomal recessive gene that delays expression of lupus in BXSB mice. Kofler, R., McConahey, P.J., Duchosal, M.A., Balderas, R.S., Theofilopoulos, A.N., Dixon, F.J. J. Immunol. (1991) [Pubmed]
  17. Leukocyte-suppressing influences of interleukin (IL)-10 in cardiac allografts: insights from IL-10 knockout mice. Räisänen-Sokolowski, A., Glysing-Jensen, T., Russell, M.E. Am. J. Pathol. (1998) [Pubmed]
  18. Macrophage migration inhibitory factor expression in human renal allograft rejection. Lan, H.Y., Yang, N., Brown, F.G., Isbel, N.M., Nikolic-Paterson, D.J., Mu, W., Metz, C.N., Bacher, M., Atkins, R.C., Bucala, R. Transplantation (1998) [Pubmed]
  19. Visual recovery in two patients after intravenous methylprednisolone treatment of central retinal artery occlusion secondary to giant-cell arteritis. Matzkin, D.C., Slamovits, T.L., Sachs, R., Burde, R.M. Ophthalmology (1992) [Pubmed]
  20. Tolerance induced without immunosuppression in a T-lymphocyte suicide-gene therapy cardiac allograft model in mice. Braunberger, E., Raynal-Raschilas, N., Thomas-Vaslin, V., Bruneval, P., Fabiani, J.N., Carpentier, A., Glotz, D., Klatzmann, D. J. Thorac. Cardiovasc. Surg. (2000) [Pubmed]
  21. YKL-40 in giant cells and macrophages from patients with giant cell arteritis. Johansen, J.S., Baslund, B., Garbarsch, C., Hansen, M., Stoltenberg, M., Lorenzen, I., Price, P.A. Arthritis Rheum. (1999) [Pubmed]
  22. Interferon-gamma-producing T cells in giant cell vasculitis represent a minority of tissue-infiltrating cells and are located distant from the site of pathology. Wagner, A.D., Björnsson, J., Bartley, G.B., Goronzy, J.J., Weyand, C.M. Am. J. Pathol. (1996) [Pubmed]
  23. Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis. Foell, D., Hernández-Rodríguez, J., Sánchez, M., Vogl, T., Cid, M.C., Roth, J. J. Pathol. (2004) [Pubmed]
  24. Terminal complement components mediate release of von Willebrand factor and adhesion of platelets in arteries of allografts. Ota, H., Fox-Talbot, K., Hu, W., Qian, Z., Sanfilippo, F., Hruban, R.H., Baldwin, W.M. Transplantation (2005) [Pubmed]
  25. Thrombotic microangiopathy associated with the hypereosinophilic syndrome. Liapis, H., Ho, A.K., Brown, D., Mindel, G., Gleich, G. Kidney Int. (2005) [Pubmed]
  26. HLA-DRB1 alleles in polymyalgia rheumatica, giant cell arteritis, and rheumatoid arthritis. Weyand, C.M., Hunder, N.N., Hicok, K.C., Hunder, G.G., Goronzy, J.J. Arthritis Rheum. (1994) [Pubmed]
  27. S100A8 and S100A9 in human arterial wall. Implications for atherogenesis. McCormick, M.M., Rahimi, F., Bobryshev, Y.V., Gaus, K., Zreiqat, H., Cai, H., Lord, R.S., Geczy, C.L. J. Biol. Chem. (2005) [Pubmed]
  28. TLR2 and MyD88 contribute to Lactobacillus casei extract-induced focal coronary arteritis in a mouse model of Kawasaki disease. Rosenkranz, M.E., Schulte, D.J., Agle, L.M., Wong, M.H., Zhang, W., Ivashkiv, L., Doherty, T.M., Fishbein, M.C., Lehman, T.J., Michelsen, K.S., Arditi, M. Circulation (2005) [Pubmed]
  29. Expression of DARC, CXCR3 and CCR5 in giant cell arteritis. Brühl, H., Vielhauer, V., Weiss, M., Mack, M., Schlöndorff, D., Segerer, S. Rheumatology (Oxford, England) (2005) [Pubmed]
  30. Estrogen receptors in giant cell arteritis. An immunocytochemical, western blot and RT-PCR study. Petursdottir, V., Nordborg, E., Moraghebi, N., Persson, M., Nordborg, C. Clinical and experimental rheumatology. (1999) [Pubmed]
  31. The Tsukuba hypertensive mouse (transgenic mouse carrying human genes for both renin and angiotensinogen) as a model of human malignant hypertension: development of lesions and morphometric analysis. Shimokama, T., Haraoka, S., Horiguchi, H., Sugiyama, F., Murakami, K., Watanabe, T. Virchows Arch. (1998) [Pubmed]
  32. The liver in collagen diseases: pathologic study of 160 cases with particular reference to hepatic arteritis, primary biliary cirrhosis, autoimmune hepatitis and nodular regenerative hyperplasia of the liver. Matsumoto, T., Kobayashi, S., Shimizu, H., Nakajima, M., Watanabe, S., Kitami, N., Sato, N., Abe, H., Aoki, Y., Hoshi, T., Hashimoto, H. Liver (2000) [Pubmed]
  33. Pathological evaluation of steroid withdrawal in pediatric renal transplant recipients. Aikawa, A., Miyagi, M., Motoyama, O., Shigetomi, Y., Ohara, T., Hirayama, N., Kawamura, S., Hasegawa, A. Pediatric transplantation. (1999) [Pubmed]
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