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MeSH Review

Optic Neuritis

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Disease relevance of Optic Neuritis


High impact information on Optic Neuritis


Chemical compound and disease context of Optic Neuritis


Biological context of Optic Neuritis


Anatomical context of Optic Neuritis


Gene context of Optic Neuritis


Analytical, diagnostic and therapeutic context of Optic Neuritis


  1. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. Bettelli, E., Pagany, M., Weiner, H.L., Linington, C., Sobel, R.A., Kuchroo, V.K. J. Exp. Med. (2003) [Pubmed]
  2. Adeno-associated viral-mediated catalase expression suppresses optic neuritis in experimental allergic encephalomyelitis. Guy, J., Qi, X., Hauswirth, W.W. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  3. Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology. Storch, M.K., Stefferl, A., Brehm, U., Weissert, R., Wallström, E., Kerschensteiner, M., Olsson, T., Linington, C., Lassmann, H. Brain Pathol. (1998) [Pubmed]
  4. Transverse myelitis and optic neuritis in systemic lupus erythematosus: a case report with magnetic resonance imaging findings. Kenik, J.G., Krohn, K., Kelly, R.B., Bierman, M., Hammeke, M.D., Hurley, J.A. Arthritis Rheum. (1987) [Pubmed]
  5. Optic nueritis in hypoparathyroidism. Bajandas, F.J., Smith, J.L. Neurology (1976) [Pubmed]
  6. A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis. The Optic Neuritis Study Group. Beck, R.W., Cleary, P.A., Anderson, M.M., Keltner, J.L., Shults, W.T., Kaufman, D.I., Buckley, E.G., Corbett, J.J., Kupersmith, M.J., Miller, N.R. N. Engl. J. Med. (1992) [Pubmed]
  7. Optic neuritis associated with dideoxyinosine. Lafeuillade, A., Aubert, L., Chaffanjon, P., Quilichini, R. Lancet (1991) [Pubmed]
  8. Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis. Sättler, M.B., Merkler, D., Maier, K., Stadelmann, C., Ehrenreich, H., Bähr, M., Diem, R. Cell Death Differ. (2004) [Pubmed]
  9. Ciliary neurotrophic factor protects retinal ganglion cells from secondary cell death during acute autoimmune optic neuritis in rats. Maier, K., Rau, C.R., Storch, M.K., Sättler, M.B., Demmer, I., Weissert, R., Taheri, N., Kuhnert, A.V., Bähr, M., Diem, R. Brain Pathol. (2004) [Pubmed]
  10. The pathophysiology of acute optic neuritis. An association of gadolinium leakage with clinical and electrophysiological deficits. Youl, B.D., Turano, G., Miller, D.H., Towell, A.D., MacManus, D.G., Moore, S.G., Jones, S.J., Barrett, G., Kendall, B.E., Moseley, I.F. Brain (1991) [Pubmed]
  11. Cyclophosphamide pulse therapy in optic neuritis due to systemic lupus erythematosus: an open trial. Galindo-Rodríguez, G., Aviña-Zubieta, J.A., Pizarro, S., Díaz de León, V., Saucedo, N., Fuentes, M., Lavalle, C. Am. J. Med. (1999) [Pubmed]
  12. Increase of manganese superoxide dismutase, but not of Cu/Zn-SOD, in experimental optic neuritis. Qi, X., Guy, J., Nick, H., Valentine, J., Rao, N. Invest. Ophthalmol. Vis. Sci. (1997) [Pubmed]
  13. Bilateral postinfectious optic neuritis and intravenous steroid therapy in children. Farris, B.K., Pickard, D.J. Ophthalmology (1990) [Pubmed]
  14. Cognitive event-related potentials in multiple sclerosis. Newton, M.R., Barrett, G., Callanan, M.M., Towell, A.D. Brain (1989) [Pubmed]
  15. Eye movement disorders in multiple sclerosis and optic neuritis. Reulen, J.P., Sanders, E.A., Hogenhuis, L.A. Brain (1983) [Pubmed]
  16. Visual field abnormalities in multiple sclerosis. Patterson, V.H., Heron, J.R. J. Neurol. Neurosurg. Psychiatr. (1980) [Pubmed]
  17. Magnetic resonance imaging, evoked responses and cerebrospinal fluid findings in a follow-up study of children with optic neuritis. Riikonen, R., Ketonen, L., Sipponen, J. Acta neurologica Scandinavica. (1988) [Pubmed]
  18. Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis. Sellebjerg, F., Christiansen, M., Jensen, J., Frederiksen, J.L. Eur. J. Neurol. (2000) [Pubmed]
  19. Cerebrospinal fluid antibodies to myelin basic protein in acute idiopathic optic neuritis. Warren, K.G., Catz, I., Bauer, C. Ann. Neurol. (1988) [Pubmed]
  20. Two subsets of dendritic cells are present in human cerebrospinal fluid. Pashenkov, M., Huang, Y.M., Kostulas, V., Haglund, M., Söderström, M., Link, H. Brain (2001) [Pubmed]
  21. Retrobulbar neuritis. In vitro evidence of sensitization to myelin basic protein in patients without multiple sclerosis. Sheremata, W., Younge, B., Eylar, E.H. Neurology (1977) [Pubmed]
  22. Simvastatin treatment does not protect retinal ganglion cells from degeneration in a rat model of autoimmune optic neuritis. Sättler, M.B., Diem, R., Merkler, D., Demmer, I., Boger, I., Stadelmann, C., Bähr, M. Exp. Neurol. (2005) [Pubmed]
  23. Lack of restriction of T cell receptor beta variable gene usage in cerebrospinal fluid lymphocytes in acute optic neuritis. Heard, R.N., Teutsch, S.M., Bennetts, B.H., Lee, S.D., Deane, E.M., Stewart, G.J. J. Neurol. Neurosurg. Psychiatr. (1999) [Pubmed]
  24. Anti-myelin basic protein and anti-proteolipid protein specific forms of multiple sclerosis. Warren, K.G., Catz, I., Johnson, E., Mielke, B. Ann. Neurol. (1994) [Pubmed]
  25. Optic neuritis is associated with myelin basic protein and proteolipid protein reactive cells producing interferon-gamma, interleukin-4 and transforming growth factor-beta. Link, J., Söderström, M., Kostulas, V., Olsson, T., Höjeberg, B., Ljungdahl, A., Link, H. J. Neuroimmunol. (1994) [Pubmed]
  26. Characterization of the mitochondrial genome in childhood multiple sclerosis. II. Multiple sclerosis without optic neuritis and LHON-associated genes. Wilichowski, E., Ohlenbusch, A., Hanefeld, F. Neuropediatrics. (1998) [Pubmed]
  27. Optic neuritis: chemokine receptor CXCR3 and its ligands. Sørensen, T.L., Roed, H., Sellebjerg, F. The British journal of ophthalmology. (2004) [Pubmed]
  28. Chemokine CCL2 and chemokine receptor CCR2 in early active multiple sclerosis. Sørensen, T.L., Ransohoff, R.M., Strieter, R.M., Sellebjerg, F. Eur. J. Neurol. (2004) [Pubmed]
  29. Optic neuritis after anthrax vaccination. Kerrison, J.B., Lounsbury, D., Thirkill, C.E., Lane, R.G., Schatz, M.P., Engler, R.M. Ophthalmology (2002) [Pubmed]
  30. Adenoviral gene therapy with catalase suppresses experimental optic neuritis. Guy, J., Qi, X., Wang, H., Hauswirth, W.W. Arch. Ophthalmol. (1999) [Pubmed]
  31. The Aulhorn flicker test: possibilities and limits. Its use in optic neuritis for diagnosis, differential diagnosis, monitoring the course of the disease, and assessing the effect of oral prednisolone. Trauzettel-Klosinski, S. German journal of ophthalmology. (1992) [Pubmed]
  32. Human T-cell lymphotropic virus type-I associated myelopathy complicated by optic neuritis. Komaba, Y., Kitamura, S., Terashi, A., Tamotsu, M., Nakatani, Y., Hara, A. Nippon Ika Daigaku Zasshi (1996) [Pubmed]
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