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MeSH Review

Gorilla gorilla

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High impact information on Gorilla gorilla

  • The evolutionary relationships among the MHC class II DRB4, DRB5 and DRB6 loci as well as the allelic lineages and alleles of the DRB1 locus were studied based on intron 1 and intron 2 sequences from humans, chimpanzee (Pan troglodytes), bonobo (Pan paniscus) and gorilla (Gorilla gorilla) [1].
  • After comparison with the COII gene of gorilla specimens with known geographical origin, the sequence was identified as characteristic of the Western lowland gorilla, Gorilla gorilla gorilla [2].
  • A 6.0-kb DNA fragment from Gorilla gorilla including the 5' part of the beta-globin gene and about 4.5 kb of its upstream flanking region was cloned and sequenced [3].
  • At the protein level, Homo sapiens differs from Gorilla gorilla only at 4 of 609 amino acid positions (0.66%) in the alpha-fetoprotein sequence [4].
  • In fibroblasts from gorilla (Gorilla gorilla) using biotin labelling, a single site of hybridisation occurred at 1qter which provides further support for homology of 1q in the higher apes and human 1p [5].

Biological context of Gorilla gorilla

  • Urinary estrogen components were separated, identified and quantified throughout the pregnancy of the gorilla (Gorilla gorilla) and orangutan (Pongo pygmaeus) and compared to estrogen levels in normal human pregnancies [6].
  • We assessed this variability by sequencing and discovering SNPs in 5'-upstream, 5'-untranslated region (5'UTR), exon, intron, 3'UTR and 3'-downstream regions of all these genes in 79 unrelated humans from diverse ethnic backgrounds, one chimpanzee (Pan troglodytes) and a gorilla (Gorilla gorilla) [7].

Associations of Gorilla gorilla with chemical compounds


Gene context of Gorilla gorilla

  • Transporter associated with antigen-processing-1 (TAP1) alleles in Gorilla gorilla: diversification of the locus postspeciation [12].
  • The sequence of the tyrosinase (Tyr) gene coding tracts has been obtained for the gorilla (Gorilla gorilla gorilla) [13].
  • Gastrointestinal parasites of mountain gorillas (Gorilla gorilla beringei) in the Parc National des Volcans, Rwanda [11].


  1. Phylogenetic history of hominoid DRB loci and alleles inferred from intron sequences. Bergström, T.F., Erlandsson, R., Engkvist, H., Josefsson, A., Erlich, H.A., Gyllensten, U. Immunol. Rev. (1999) [Pubmed]
  2. A complete sequence of the mitochondrial genome of the western lowland gorilla. Xu, X., Arnason, U. Mol. Biol. Evol. (1996) [Pubmed]
  3. Evolution of the primate beta-globin gene region: nucleotide sequence of the delta-beta-globin intergenic region of gorilla and phylogenetic relationships between African apes and man. Perrin-Pecontal, P., Gouy, M., Nigon, V.M., Trabuchet, G. J. Mol. Evol. (1992) [Pubmed]
  4. Structure of the gorilla alpha-fetoprotein gene and the divergence of primates. Ryan, S.C., Zielinski, R., Dugaiczyk, A. Genomics (1991) [Pubmed]
  5. Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36. Boyd, E., Theriault, A., Goddard, J.P., Kalaitsidaki, M., Spathas, D.H., Connor, J.M. Hum. Genet. (1989) [Pubmed]
  6. Urinary estrogen excretion during pregnancy in the gorilla (Gorilla gorilla), orangutan (Pongo pygmaeus) and the human (Homo sapiens). Czekala, N.M., Benirschke, K., McClure, H., Lasley, B.L. Biol. Reprod. (1983) [Pubmed]
  7. Genetic variability and evolution of two pharmacologically important classes of genes. Pungliya, M.S., Salisbury, B.A., Nandabalan, K., Stephens, J.C. Pharmacogenomics (2004) [Pubmed]
  8. Patterns of oestrogen and testosterone excretion during pregnancy in a gorilla (Gorilla gorilla). Seaton, B. J. Reprod. Fertil. (1978) [Pubmed]
  9. Occlusal relief changes with molar wear in Pan troglodytes troglodytes and Gorilla gorilla gorilla. M'kirera, F., Ungar, P.S. Am. J. Primatol. (2003) [Pubmed]
  10. A preliminary investigation of urinary testosterone and cortisol levels in wild male mountain gorillas. Robbins, M.M., Czekala, N.M. Am. J. Primatol. (1997) [Pubmed]
  11. Gastrointestinal parasites of mountain gorillas (Gorilla gorilla beringei) in the Parc National des Volcans, Rwanda. Sleeman, J.M., Meader, L.L., Mudakikwa, A.B., Foster, J.W., Patton, S. J. Zoo Wildl. Med. (2000) [Pubmed]
  12. Transporter associated with antigen-processing-1 (TAP1) alleles in Gorilla gorilla: diversification of the locus postspeciation. Laud, P.R., Loflin, P.T., Jeevan, A., Lawlor, D.A. Hum. Immunol. (1996) [Pubmed]
  13. The tyrosinase gene in gorillas and the albinism of 'Snowflake'. Martínez-Arias, R., Comas, D., Andrés, A., Abelló, M.T., Domingo-Roura, X., Bertranpetit, J. Pigment Cell Res. (2000) [Pubmed]
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