Gene Review:
HLA-DRB4 - major histocompatibility complex, class II...
Homo sapiens
Synonyms:
DR-4, DR4, DRB4, HLA class II histocompatibility antigen, DR beta 4 chain, HLA-DR4B, ...
- Unravelling an HLA-DR association in childhood acute lymphoblastic leukemia. Dorak, M.T., Lawson, T., Machulla, H.K., Darke, C., Mills, K.I., Burnett, A.K. Blood (1999)
- MICA-A5.1 allele is associated with atypical forms of celiac disease in HLA-DQ2-negative patients. Lopez-Vazquez, A., Rodrigo, L., Fuentes, D., Riestra, S., Bousoño, C., Garcia-Fernandez, S., Martinez-Borra, J., Gonzalez, S., Lopez-Larrea, C. Immunogenetics (2002)
- Interactions of HLA-DRB4 and CTLA-4 genes influence thyroid function in Hashimoto's thyroiditis in Japanese population. Terauchi, M., Yanagawa, T., Ishikawa, N., Ito, K., Fukazawa, T., Maruyama, H., Saruta, T. J. Endocrinol. Invest. (2003)
- HLA-DRB3*0101 is associated with Graves' disease in Jamaicans. Smikie, M.F., Pascoe, R.W., Barton, E., Morgan, O., Christian, N., Dowe, G., Roye-Green, K., Bailey, V., James, O. Clin. Endocrinol. (Oxf) (2001)
- Association of high HIV-1 RNA levels and homozygosity at HLA class II DRB1 in adults coinfected with Mycobacterium tuberculosis in Harare, Zimbabwe. Zijenah, L.S., Hartogensis, W.E., Katzenstein, D.A., Tobaiwa, O., Mutswangwa, J., Mason, P.R., Louie, L.G. Hum. Immunol. (2002)
- Association of HLA-DR and -DQ Genes with Narcolepsy in Koreans Comparison with Two Control Groups, Randomly Selected Subjects and DRB1*1501-DQB1*0602-Positive Subjects. Roh, E.Y., Park, M.H., Park, H., Park, D.H., Choi, J.B., Kim, S.J., Jeong, D.U. Hum. Immunol. (2006)
- A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Lincoln, M.R., Montpetit, A., Cader, M.Z., Saarela, J., Dyment, D.A., Tiislar, M., Ferretti, V., Tienari, P.J., Sadovnick, A.D., Peltonen, L., Ebers, G.C., Hudson, T.J. Nat. Genet. (2005)
- HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA-DRB1*0301 (DR3) gene. Kong, Y.C., Lomo, L.C., Motte, R.W., Giraldo, A.A., Baisch, J., Strauss, G., Hämmerling, G.J., David, C.S. J. Exp. Med. (1996)
- The relationship between nonresponse to hepatitis B vaccine and HLA genotype/haplotype. Li, M., Li, R., Huang, S., Gong, J., Zeng, X., Li, Y., Lu, M., Li, H. Zhonghua Yu Fang Yi Xue Za Zhi (2002)
- Amino acid residue at position 13 in HLA-DR beta chain plays a critical role in the development of Kaposi's sarcoma in AIDS patients. Gayà, A., Esteve, A., Casabona, J., McCarthy, J.J., Martorell, J., Schulz, T.F., Whitby, D. AIDS (2004)
- Amino acid polymorphism at residue 71 in HLA-DR beta chain plays a critical role in susceptibility to ulcerative colitis. de la Concha, E.G., Fernandez-Arquero, M., Martinez, A., Vigil, P., Vidal, F., Lopez-Nava, G., Diaz-Rubio, M., Garcia-Paredes, J. Dig. Dis. Sci. (1999)
- Primate DRB6 pseudogenes: clue to the evolutionary origin of the HLA-DR2 haplotype. Figueroa, F., O'hUigin, C., Inoki, H., Klein, J. Immunogenetics (1991)
- Evolutionary relationship of HLA-DRB genes inferred from intron sequences. Satta, Y., Mayer, W.E., Klein, J. J. Mol. Evol. (1996)
- Increased heterozygosity for MHC class II lineages in newborn males. Dorak, M.T., Lawson, T., Machulla, H.K., Mills, K.I., Burnett, A.K. Genes Immun. (2002)
- Determination of HLA class II alleles by genotyping in a Manchu population in the northern part of China and its relationship with Han and Japanese populations. Geng, L., Imanishi, T., Tokunaga, K., Zhu, D., Mizuki, N., Xu, S., Geng, Z., Gojobori, T., Tsuji, K., Inoko, H. Tissue Antigens (1995)
- Mapping of a restriction fragment length polymorphism associated with defective DR beta 4 chain expression to the HLA-DRB1 gene. Sutton, V.R., Knowles, R.W. Hum. Immunol. (1988)
- HLA-restricted immune response to mycobacterial antigens: relevance to vaccine design. Mustafa, A.S. Hum. Immunol. (2000)
- Differential surface expression of HLA-DRB1 and HLA-DRB4 among peripheral blood cells of DR4 positive individuals. Czerwony, G., Alten, R., Gromnica-Ihle, E., Hagemann, D., Reuter, U., Sörensen, H., Müller, B. Hum. Immunol. (1999)
- HLA-DRB1 and -DRB4 genes are differentially regulated at the transcriptional level. Stunz, L.L., Karr, R.W., Anderson, R.A. J. Immunol. (1989)
- Molecular, serological and genetic studies on two new HLA-DRB1 alleles--HLA-DRB1*0704 and HLA-DRB1*1507. Darke, C., Guttridge, M.G., Street, J., Thompson, J., Thomas, M. Tissue Antigens (2000)
- Antigen presentation of the immunodominant T-cell epitope of the major mugwort pollen allergen, Art v 1, is associated with the expression of HLA-DRB1 *01. Jahn-Schmid, B., Fischer, G.F., Bohle, B., Faé, I., Gadermaier, G., Dedic, A., Ferreira, F., Ebner, C. J. Allergy Clin. Immunol. (2005)
- Roles of DRB1( *)1501 and DRB1( *)1502 in the pathogenesis of aplastic anemia. Sugimori, C., Yamazaki, H., Feng, X., Mochizuki, K., Kondo, Y., Takami, A., Chuhjo, T., Kimura, A., Teramura, M., Mizoguchi, H., Omine, M., Nakao, S. Exp. Hematol. (2007)
- HLA-DRB1 genes and disease severity in rheumatoid arthritis. The MIRA Trial Group. Minocycline in Rheumatoid Arthritis. Reveille, J.D., Alarcón, G.S., Fowler, S.E., Pillemer, S.R., Neuner, R., Clegg, D.O., Mikhail, I.S., Trentham, D.E., Leisen, J.C., Bluhm, G., Cooper, S.M., Duncan, H., Tuttleman, M., Heyse, S.P., Sharp, J.T., Tilley, B. Arthritis Rheum. (1996)
- The effect of HLA-DRB1 genes, rheumatoid factor, and treatment on radiographic disease progression in rheumatoid arthritis over 6 years. Rau, R., Herborn, G., Zueger, S., Fenner, H. J. Rheumatol. (2000)
- HLA-DRB1 gene polymorphism in patients with dilated cardiomyopathy. Wang, Q., Liao, Y., Gong, F., Mao, H., Zhang, J. J. Tongji Med. Univ. (2000)
- HLA-DRB genotypes in Japanese patients with renal cell carcinoma. Kojima, Y., Takahara, S., Nonomura, N., Sada, M., Tsuji, T., Hatori, M., Fujioka, H., Kuroda, H., Miki, T., Okuyama, A. Oncology (2000)
- HLA-DRB4 genotyping by PCR-RFLP: diversity in the associations between HLA-DRB4 and DRB1 alleles. Naruse, T.K., Ando, R., Nose, Y., Kagiya, M., Ando, H., Kawata, H., Nabeya, N., Isshiki, G., Inoko, H. Tissue Antigens (1997)
- The HLA-DRB4 gene is present in half of the Spanish HLA-DQ2-negative celiac patients. Garrote, J.A., Arranz, E., Blanco-Quirós, A. Immunogenetics (2000)
- Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP). Bunce, M., O'Neill, C.M., Barnardo, M.C., Krausa, P., Browning, M.J., Morris, P.J., Welsh, K.I. Tissue Antigens (1995)
- Specific amplification of the HLA-DRB4 gene from c-DNA. Complete coding sequence of the HLA alleles DRB4*0103101 and DRB4*01033. De Pablo, R., Solís, R., Balas, A., Vilches, C. Tissue Antigens (2002)
- Genetic analysis of the HLA region of Japanese patients with type 1 autoimmune hepatitis. Yoshizawa, K., Ota, M., Katsuyama, Y., Ichijo, T., Matsumoto, A., Tanaka, E., Kiyosawa, K. J. Hepatol. (2005)
- DNA typing for HLA-A and HLA-B identifies disparities between patients and unrelated donors matched by HLA-A and HLA-B serology and HLA-DRB1. Prasad, V.K., Kernan, N.A., Heller, G., O'Reilly, R.J., Yang, S.Y. Blood (1999)