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Chemical Compound Review

CCRIS 1862     (1R)-7-(hydroxymethyl)-2,3- dihydro-1H...

Synonyms: KST-1A2999, AC1L2XXB, AR-1A1027, LS-143480, AKOS006273170, ...
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Disease relevance of Retronecine pyrrole


High impact information on Retronecine pyrrole


Biological context of Retronecine pyrrole


Anatomical context of Retronecine pyrrole


Associations of Retronecine pyrrole with other chemical compounds


Gene context of Retronecine pyrrole


Analytical, diagnostic and therapeutic context of Retronecine pyrrole


  1. Neoplastic transformation in tissues of rats exposed to monocrotaline or dehydroretronecine. Shumaker, R.C., Robertson, K.A., Hsu, I.C., Allen, J.R. J. Natl. Cancer Inst. (1976) [Pubmed]
  2. Correlation of DNA adduct formation and riddelliine-induced liver tumorigenesis in F344 rats and B6C3F1 mice [Cancer Lett. 193 (2003) 119-125. Chou, M.W., Yan, J., Nichols, J., Xia, Q., Beland, F.A., Chan, P.C., Fu, P.P. Cancer Lett. (2004) [Pubmed]
  3. Tissue distribution, binding properties and lesions produced by dehydroretronecine in the nonhuman primate. Hsu, I.C., Robertson, K.A., Allen, J.R. Chem. Biol. Interact. (1976) [Pubmed]
  4. Alkylation of N2 in deoxyguanosine by dehydroretronecine, a carcinogenic metabolite of the pyrrolizidine alkaloid monocrotaline. Robertson, K.A. Cancer Res. (1982) [Pubmed]
  5. The effect of a pyrrolizidine alkaloid, monocrotaline, and a pyrrole, dehydroretronecine, on the biochemical functions of the pulmonary endothelium. Huxtable, R., Ciaramitaro, D., Eisenstein, D. Mol. Pharmacol. (1978) [Pubmed]
  6. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo. Yang, Y.C., Yan, J., Doerge, D.R., Chan, P.C., Fu, P.P., Chou, M.W. Chem. Res. Toxicol. (2001) [Pubmed]
  7. Deacetylclivorine: a gender-selective metabolite of clivorine formed in female sprague-dawley rat liver microsomes. Lin, G., Tang, J., Liu, X.Q., Jiang, Y., Zheng, J. Drug Metab. Dispos. (2007) [Pubmed]
  8. A new pyrrolizidine alkaloid metabolite, 19-hydroxysenecionine isolated from mouse hepatic microsomes in vitro. Eastman, D.F., Segall, H.J. Drug Metab. Dispos. (1982) [Pubmed]
  9. Binding of tritiated dehydroretronecine to macromolecules. Hsu, I.C., Robertson, K.A., Shumaker, R.C., Allen, J.R. Res. Commun. Chem. Pathol. Pharmacol. (1975) [Pubmed]
  10. Two dihydropyrrolizine alkaloid metabolites isolated from mouse hepatic microsomes in vitro. Segall, H.J., Dallas, J.L., Haddon, W.F. Drug Metab. Dispos. (1984) [Pubmed]
  11. Microsomal formation of a pyrrolic alcohol glutathione conjugate of the pyrrolizidine alkaloid senecionine. Reed, R.L., Miranda, C.L., Kedzierski, B., Henderson, M.C., Buhler, D.R. Xenobiotica (1992) [Pubmed]
  12. Inhibition of yeast alcohol dehydrogenase by dehydroretronecine. Sun, P.S., Hsia, M.T., Chu, F.S., Allen, J.R. Food and cosmetics toxicology. (1977) [Pubmed]
  13. Development of a (32)P-postlabeling/HPLC method for detection of dehydroretronecine-derived DNA adducts in vivo and in vitro. Yang, Y., Yan, J., Churchwell, M., Beger, R., Chan, P., Doerge, D.R., Fu, P.P., Chou, M.W. Chem. Res. Toxicol. (2001) [Pubmed]
  14. Quantitation of the hepatic release of metabolites of the pyrrolizidine alkaloid, monocrotaline. Yan, C.C., Huxtable, R.J. Toxicol. Appl. Pharmacol. (1994) [Pubmed]
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