Chemical Compound Review:
deoxyguanosine 2-amino-9-[4-hydroxy-5...
Synonyms:
ACMC-1C8JT, AG-D-37261, D8415_SIGMA, NSC-22837, SureCN10068103, ...
- Deoxyguanosine toxicity in a mouse T lymphoma: relationship to purine nucleoside phosphorylase-associated immune dysfunction. Gudas, L.J., Ullman, B., Cohen, A., Martin, D.W. Cell (1978)
- Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Tomasz, M., Lipman, R., Chowdary, D., Pawlak, J., Verdine, G.L., Nakanishi, K. Science (1987)
- A unique deoxyguanosine triphosphatase is responsible for the optA1 phenotype of Escherichia coli. Beauchamp, B.B., Richardson, C.C. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Inhibition of the replication of hepatitis B virus by the carbocyclic analogue of 2'-deoxyguanosine. Price, P.M., Banerjee, R., Acs, G. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Selective toxicity of deoxyguanosine and arabinosyl guanine for T-leukemic cells. Cohen, A., Lee, J.W., Gelfand, E.W. Blood (1983)
- Deoxyguanosine toxicity on lymphoid cells as a cause for immunosuppression in purine nucleoside phosphorylase deficiency. Chan, T.S. Cell (1978)
- Positive selection of CD4+ T cells mediated by MHC class II-bearing stromal cell in the thymic cortex. Bill, J., Palmer, E. Nature (1989)
- Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Kuchino, Y., Mori, F., Kasai, H., Inoue, H., Iwai, S., Miura, K., Ohtsuka, E., Nishimura, S. Nature (1987)
- Identity of cells that imprint H-2-restricted T-cell specificity in the thymus. Lo, D., Sprent, J. Nature (1986)
- Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts. Kazmers, I.S., Mitchell, B.S., Dadonna, P.E., Wotring, L.L., Townsend, L.B., Kelley, W.N. Science (1981)
- Deoxyadenosine triphosphate as a mediator of deoxyguanosine toxicity in cultured T lymphoblasts. Mann, G.J., Fox, R.M. J. Clin. Invest. (1986)
- Deoxyribonucleoside triphosphate accumulation by leukemic cells. Mitchell, B.S., Edwards, N.L., Koller, C.A. Blood (1983)
- 2,6-Diaminopurinedeoxyriboside as a prodrug of deoxyguanosine in L1210 cells. Weckbecker, G., Cory, J.G. Cancer Res. (1987)
- Inhibition of hepatitis B virus DNA polymerase by enantiomers of penciclovir triphosphate and metabolic basis for selective inhibition of HBV replication by penciclovir. Shaw, T., Mok, S.S., Locarnini, S.A. Hepatology (1996)
- An erythrocyte-specific protein that binds to the poly(dG) region of the chicken beta-globin gene promoter. Lewis, C.D., Clark, S.P., Felsenfeld, G., Gould, H. Genes Dev. (1988)
- Oxidant-induced DNA damage of target cells. Schraufstätter, I., Hyslop, P.A., Jackson, J.H., Cochrane, C.G. J. Clin. Invest. (1988)
- Human fibroblast chromatin states as effectors of the DNA-binding characteristics of benzo[a]pyrene anti-7,8-dihydrodiol 9,10-epoxide and two nonalkylating DNA-binding molecules. Warner, M.R., Iannaccone, P., Fahl, W.E. J. Natl. Cancer Inst. (1986)
- Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes. Kicska, G.A., Long, L., Hörig, H., Fairchild, C., Tyler, P.C., Furneaux, R.H., Schramm, V.L., Kaufman, H.L. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Inhibition of suppressor T-cell development following deoxyguanosine administration. Dosch, H.M., Mansour, A., Cohen, A., Shore, A., Gelfand, E.W. Nature (1980)
- Thymic epithelium and the induction of transplantation tolerance in nude mice. Jordan, R.K., Robinson, J.H., Hopkinson, N.A., House, K.C., Bentley, A.L. Nature (1985)
- Involvement of E-cadherin in thymus organogenesis and thymocyte maturation. Müller, K.M., Luedecker, C.J., Udey, M.C., Farr, A.G. Immunity (1997)
- Ecto-adenosine triphosphatase deficiency in cultured human T and null leukemic lymphocytes. A biochemical basis for thymidine sensitivity. Fox, R.M., Piddington, S.K., Tripp, E.H., Tattersall, M.H. J. Clin. Invest. (1981)
- Design of vectors for efficient expression of human purine nucleoside phosphorylase in skin fibroblasts from enzyme-deficient humans. Osborne, W.R., Miller, A.D. Proc. Natl. Acad. Sci. U.S.A. (1988)
- 2'-deoxyguanosine toxicity for B and mature T lymphoid cell lines is mediated by guanine ribonucleotide accumulation. Sidi, Y., Mitchell, B.S. J. Clin. Invest. (1984)
- Purinogenic immunodeficiency diseases: clinical features and molecular mechanisms. Mitchell, B.S., Kelley, W.N. Ann. Intern. Med. (1980)
- Deoxycytidine kinase and deoxyguanosine kinase of Lactobacillus acidophilus R-26 are colinear products of a single gene. Ma, N., Ikeda, S., Guo, S., Fieno, A., Park, I., Grimme, S., Ikeda, T., Ives, D.H. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Importance of specific purine amino and hydroxyl groups for efficient cleavage by a hammerhead ribozyme. Fu, D.J., McLaughlin, L.W. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. Hagen, T.M., Huang, S., Curnutte, J., Fowler, P., Martinez, V., Wehr, C.M., Ames, B.N., Chisari, F.V. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Pro-T cells in fetal thymus express c-kit and RAG-2 but do not rearrange the gene encoding the T cell receptor beta chain. Hozumi, K., Kobori, A., Sato, T., Nozaki, H., Nishikawa, S., Nishimura, T., Habu, S. Eur. J. Immunol. (1994)
- T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7. Christianson, S.W., Greiner, D.L., Deluca, D., Leif, J., Phillips, N.E., Hayes, S.M., Hayashi, S., Joliat, M.J., Lyons, B.L., Shultz, L.D. J. Autoimmun. (2002)
- Genetic changes and expression of the mannose 6-phosphate/insulin-like growth factor II receptor gene in human hepatitis B virus-associated hepatocellular carcinoma. Yang, E.B., Qin, L.L., Zhao, Y.N., Zhang, K., Chow, P. Int. J. Mol. Med. (2003)
- Effect of oxidative stress on DNA damage and beta-amyloid precursor proteins in lymphoblastoid cell lines from a Nigerian population. Lahiri, D.K., Xu, Y., Klaunig, J., Baiyewu, O., Ogunniyi, A., Hall, K., Hendrie, H., Sahota, A. Ann. N. Y. Acad. Sci. (1999)
- Nucleoside kinases in T and B lymphoblasts distinguished by autoradiography. Osborne, W.R. Proc. Natl. Acad. Sci. U.S.A. (1986)
- A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations. Kingston, R., Jenkinson, E.J., Owen, J.J. Nature (1985)
- Transcription of granzyme A and B genes is differentially regulated during lymphoid ontogeny. Ebnet, K., Levelt, C.N., Tran, T.T., Eichmann, K., Simon, M.M. J. Exp. Med. (1995)
- Benzo[alpha]pyrene diol epoxide I binds to DNA at replication forks. Paules, R.S., Cordeiro-Stone, M., Mass, M.J., Poirier, M.C., Yuspa, S.H., Kaufman, D.G. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues. Santella, R.M., Grunberger, D., Weinstein, I.B., Rich, A. Proc. Natl. Acad. Sci. U.S.A. (1981)
- O6-alkyldeoxyguanosine detection by 32P-postlabeling and nucleotide chromatographic analysis. Wilson, V.L., Basu, A.K., Essigmann, J.M., Smith, R.A., Harris, C.C. Cancer Res. (1988)