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Chemical Compound Review:

AR-1I7778 ethene; ethenol

Synonyms: AC1L3U0J, AC1Q59ZW, 414077_ALDRICH, 414085_ALDRICH, 414093_ALDRICH, ...

Hörl, W.H. et al., Hörl, W.H. et al., Oyane, A. et al., Schirmer, C.M. et al., Matthes, K. et al., et al.

Oyane, Minoda, Miyamoto, Takahashi, Nakanishi, Kim, Kokubo, Nakamura, Oyane, Uchida, Ito, Oyane, Uchida, Onuma, Ito, Linfante, Wakhloo,

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Disease relevance of ethylene-vinyl alcohol copolymer

The purpose of this study was to assess the feasibility of endovascular treatment of aneurysms with high-concentration ethylene-vinyl alcohol copolymer (HCEVOH), without the use of protection devices at the neck [1].
Antitumor effect of implanted ethylene-vinyl alcohol copolymer matrices containing anticancer agents on Ehrlich ascites carcinoma and P388 leukemia in mice [2].
The effect of different dialyzer membrane materials (cuprophan, cellulose hydrate, polyacrylonitrile, polymethylmethacrylate, ethylene-vinyl alcohol copolymer) on the ultrafiltrate proteinase activity was investigated in 26 patients with acute renal failure (ARF) and 40 patients undergoing regular hemodialysis treatment (RDT) [3].
In addition, embolization materials such as n-butyl cyanoacrylate and ethylene-vinyl alcohol copolymer are now routinely injected to safely reduce or obliterate large and complex arteriovenous malformations and fistulae [4].

High impact information on ethylene-vinyl alcohol copolymer

The following membranes induce a reaction of increasing intensity: polyacrylonitrile, ethylene-vinyl alcohol copolymer, cuprophan, polymethylmethacrylate, and cellulose hydrate [5].
We have previously reported that a laminin-apatite composite layer is formed on an ethylene-vinyl alcohol copolymer (EVOH) in a laminin-containing calcium phosphate (LCP) solution [6].
The surfaces of ethylene-vinyl alcohol copolymer (EVOH) substrates were modified with silanol (Si-OH) groups, and their apatite forming ability was examined in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma or in a solution with ion concentrations 1.5 times those of SBF (1.5SBF) [7].
The asparagus was heated in trays of ethylene-vinyl alcohol copolymer for selected time intervals at four temperatures ranging from 110 to 125 degrees C. It was found that the rate of degradation followed first-order kinetics [8].
Proteinase activity of ultrafiltrates obtained from ARF patients was significantly enhanced with the dialyzer KF 101 (ethylene-vinyl alcohol copolymer) [3].

Biological context of ethylene-vinyl alcohol copolymer

Laminin-apatite composite coating to enhance cell adhesion to ethylene-vinyl alcohol copolymer [9].

Anatomical context of ethylene-vinyl alcohol copolymer

We determined the feasibility of endoscopic ultrasound (EUS)-guided Enteryx (EVAL/ethylene-vinyl alcohol copolymer) embolization of the portal vein (EUS-PVE) in an animal model as a potential, minimally invasive, endoscopic technique [10].

Associations of ethylene-vinyl alcohol copolymer with other chemical compounds

The six haemodialyser membranes used were cuproammonium rayon (CL-S12W), cellulose acetate (Duo-Flux HP and FF-22), ethylene-vinyl alcohol copolymer (KF-101-15), polyacrylonitrile (H12-2400S) and polymethyl methacrylate (BK2.0H) [11].
Basic studies on controlled transdermal delivery of nicardipine hydrochloride using ethylene-vinyl acetate and ethylene-vinyl alcohol copolymer membranes [12].

Analytical, diagnostic and therapeutic context of ethylene-vinyl alcohol copolymer

During hemodialysis plasma E-alpha 1PI values rose to a peak 643.0 +/- 174.7 ng/ml in patients on polymethylmethacrylate dialyzers, to 557.5 +/- 120.0 ng/ml on cuprophan dialyzers, but to only 381.9 +/- 54.0 ng/ml on ethylene-vinyl alcohol copolymer dialyzers [5].
It is recommended that Ta-NBCA be used instead of Onyx in situations mandating the use of a liquid embolic and high-energy electrocautery, pending the development of a safer radiopacifier for use with ethylene-vinyl alcohol copolymer [13].

References

High-concentration ethylene-vinyl alcohol copolymer and endovascular treatment of experimental aneurysms: feasibility of embolization without protection devices at the neck. Raymond, J., Salazkin, I., Metcalfe, A., Guilbert, F., Weill, A., Roy, D. AJNR. American journal of neuroradiology. (2003) [Pubmed]
Antitumor effect of implanted ethylene-vinyl alcohol copolymer matrices containing anticancer agents on Ehrlich ascites carcinoma and P388 leukemia in mice. Miyazaki, S., Takeuchi, S., Hou, W.M., Hashiguchi, N., Yokouchi, C., Takada, M., Hosokawa, M., Koga, Y., Kobayashi, H. Chem. Pharm. Bull. (1985) [Pubmed]
Detection of a metalloproteinase in patients with acute and chronic renal failure. Hörl, W.H., Wanner, C., Thaiss, F., Schollmeyer, P. American journal of nephrology. (1986) [Pubmed]
Brain aneurysms and arteriovenous malformations: advancements and emerging treatments in endovascular embolization. Linfante, I., Wakhloo, A.K. Stroke (2007) [Pubmed]
Plasma levels of granulocyte elastase during hemodialysis: effects of different dialyzer membranes. Hörl, W.H., Steinhauer, H.B., Schollmeyer, P. Kidney Int. (1985) [Pubmed]
Spontaneous growth of a laminin-apatite nano-composite in a metastable calcium phosphate solution. Oyane, A., Uchida, M., Onuma, K., Ito, A. Biomaterials (2006) [Pubmed]
Apatite formation on ethylene-vinyl alcohol copolymer modified with silanol groups. Oyane, A., Minoda, M., Miyamoto, T., Takahashi, R., Nakanishi, K., Kim, H.M., Kokubo, T., Nakamura, T. J. Biomed. Mater. Res. (1999) [Pubmed]
Kinetics of ascorbic acid degradation in green asparagus during heat processing. Esteve, M.J., Frígola, A., Martorell, L., Rodrigo, C. J. Food Prot. (1998) [Pubmed]
Laminin-apatite composite coating to enhance cell adhesion to ethylene-vinyl alcohol copolymer. Oyane, A., Uchida, M., Ito, A. Journal of biomedical materials research. Part A. (2005) [Pubmed]
Feasibility of endoscopic ultrasound-guided portal vein embolization with Enteryx. Matthes, K., Sahani, D., Holalkere, N.S., Mino-Kenudson, M., Brugge, W.R. Acta Gastroenterol. Belg. (2005) [Pubmed]
Comparison of serum protein removal in haemodialysis therapy by partly protein-permeable haemodialysers. Chiu, W.Y., Yamada, K., Saito, A., Ogawa, H., Takagi, T., Chung, T.G. J. Chromatogr. (1988) [Pubmed]
Basic studies on controlled transdermal delivery of nicardipine hydrochloride using ethylene-vinyl acetate and ethylene-vinyl alcohol copolymer membranes. Morimoto, Y., Seki, T., Sugibayashi, K., Juni, K., Miyazaki, S. Chem. Pharm. Bull. (1988) [Pubmed]
Electrocautery-induced Ignition of Spark Showers and Self-sustained Combustion of Onyx Ethylene-vinyl Alcohol Copolymer. Schirmer, C.M., Zerris, V., Malek, A.M. Neurosurgery (2006) [Pubmed]

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