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Chemical Compound Review

SureCN940800     1,2,4-trimethoxy-5-prop-1- enyl-benzene

Synonyms: AG-F-80107, ACMC-20alfe, AC1L2AXB, CTK1A2217, CTK8C5703, ...
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Disease relevance of Azaron


High impact information on Azaron


Biological context of Azaron

  • The IC50 values for the alpha-, beta-, and the isolated asarone were 89.7, 121.7, and 279.5 microg/ml, respectively [7].

Anatomical context of Azaron


Associations of Azaron with other chemical compounds


Analytical, diagnostic and therapeutic context of Azaron


  1. Mutagenicity testing of beta-asarone and commercial calamus drugs with Salmonella typhimurium. Göggelmann, W., Schimmer, O. Mutat. Res. (1983) [Pubmed]
  2. Antifungal activity of beta-asarone from rhizomes of Acorus gramineus. Lee, J.Y., Lee, J.Y., Yun, B.S., Hwang, B.K. J. Agric. Food Chem. (2004) [Pubmed]
  3. Rapid assessment of beta-asarone content of Acorus calamus by micellar electrokinetic capillary chromatography. Hanson, K.M., Gayton-Ely, M., Holland, L.A., Zehr, P.S., Söderberg, B.C. Electrophoresis (2005) [Pubmed]
  4. Development of gas chromatography/mass spectrometry following headspace solid-phase microextraction for fast determination of asarones in plasma. Deng, C., Lin, S., Huang, T., Duan, G., Zhang, X. Rapid Commun. Mass Spectrom. (2006) [Pubmed]
  5. Determination of beta-asarone, safrole, isosafrole and anethole in alcoholic drinks by high-performance liquid chromatography. Currò, P., Micali, G., Lanuzza, F. J. Chromatogr. (1987) [Pubmed]
  6. Chemical composition of the essential oil and supercritical CO2 extract of Commiphora myrrha (Nees) Engl. and of Acorus calamus L. Marongiu, B., Piras, A., Porcedda, S., Scorciapino, A. J. Agric. Food Chem. (2005) [Pubmed]
  7. Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus. Cho, J., Kim, Y.H., Kong, J.Y., Yang, C.H., Park, C.G. Life Sci. (2002) [Pubmed]
  8. Genotoxicity of the alkenylbenzenes alpha- and beta-asarone, myristicin and elimicin as determined by the UDS assay in cultured rat hepatocytes. Hasheminejad, G., Caldwell, J. Food Chem. Toxicol. (1994) [Pubmed]
  9. Micronucleus formation in human lymphocytes and in the metabolically competent human hepatoma cell line Hep-G2: results with 15 naturally occurring substances. Kevekordes, S., Spielberger, J., Burghaus, C.M., Birkenkamp, P., Zietz, B., Paufler, P., Diez, M., Bolten, C., Dunkelberg, H. Anticancer Res. (2001) [Pubmed]
  10. Quantitative analysis of alpha, beta-thujone, pulegone, safrole, coumarin and beta-asarone in alcoholic beverages by selected-ion monitoring. Galli, C.L., Galli, G., Tragni, E., Caruso, D., Fiecchi, A. Journal of applied toxicology : JAT. (1984) [Pubmed]
  11. Disposition of asarone after intravenous administration to rabbits assessed using HPLC. Tsai, T.H., Chen, C.M., Chen, C.F. J. Pharm. Pharmacol. (1992) [Pubmed]
  12. Quantitative determination of beta-asarone in calamus by high-performance thin-layer chromatography. Widmer, V., Schibli, A., Reich, E. Journal of AOAC International. (2005) [Pubmed]
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