Chemical Compound Review:
Pulegone 5-methyl-2-propan-2-ylidene- cyclohexan-1-one
Synonyms:
Pulegon, pulegones, Pulegone, d-, PULEGONE, (D), SureCN58181, ...
- Menthofuran-dependent and independent aspects of pulegone hepatotoxicity: roles of glutathione. Thomassen, D., Slattery, J.T., Nelson, S.D. J. Pharmacol. Exp. Ther. (1990)
- Short term toxicity study in rats dosed with pulegone and menthol. Thorup, I., Würtzen, G., Carstensen, J., Olsen, P. Toxicol. Lett. (1983)
- Antimicrobial activity of the essential oil of Calamintha nepeta and its constituent pulegone against bacteria and fungi. Flamini, G., Cioni, P.L., Puleio, R., Morelli, I., Panizzi, L. Phytotherapy research : PTR. (1999)
- Synthesis of a highly hindered hydrindanone via alpha-carbonyl radical cyclization: enantiospecific formal syntheses of (-)-pinguisenol and (-)-alpha-pinguisene. Sha, C.K., Liao, H.W., Cheng, P.C., Yen, S.C. J. Org. Chem. (2003)
- Metabolic activation of (R)-(+)-pulegone to a reactive enonal that covalently binds to mouse liver proteins. McClanahan, R.H., Thomassen, D., Slattery, J.T., Nelson, S.D. Chem. Res. Toxicol. (1989)
- Inhibitory effects of the essential oil of Mentha pulegium on the isolated rat myometrium. Soares, P.M., Assreuy, A.M., Souza, E.P., Lima, R.F., Silva, T.O., Fontenele, S.R., Criddle, D.N. Planta Med. (2005)
- Metabolism of (R)-(+)-menthofuran in Fischer-344 rats: identification of sulfonic acid metabolites. Chen, L.J., Lebetkin, E.H., Burka, L.T. Drug Metab. Dispos. (2003)
- Acaricidal activities of paeonol and benzoic acid from Paeonia suffruticosa root bark and monoterpenoids against Tyrophagus putrescentiae (Acari: Acaridae). Tak, J.H., Kim, H.K., Lee, S.H., Ahn, Y.J. Pest Manag. Sci. (2006)
- Chiral auxiliaries for asymmetric radical cyclization reactions: application to the enantioselective synthesis of (+)-triptocallol. Yang, D., Xu, M., Bian, M.Y. Org. Lett. (2001)
- In vivo and in vitro destruction of rat liver cytochrome P-450 by a monoterpene ketone, pulegone. Madyastha, P., Moorthy, B., Vaidyanathan, C.S., Madyastha, K.M. Biochem. Biophys. Res. Commun. (1985)
- Antihistaminic activity of pulegone on the guinea-pig ileum. Ortiz de Urbina, A.V., Martin, M.L., Montero, M.J., Carron, R., Sevilla, M.A., San Roman, L. J. Pharm. Pharmacol. (1990)
- Effects of drug metabolism modifiers on pulegone-induced hepatotoxicity in mice. Mizutani, T., Nomura, H., Nakanishi, K., Fujita, S. Res. Commun. Chem. Pathol. Pharmacol. (1987)
- Partial characterization of biliary metabolites of pulegone by tandem mass spectrometry. Detection of glucuronide, glutathione, and glutathionyl glucuronide conjugates. Thomassen, D., Pearson, P.G., Slattery, J.T., Nelson, S.D. Drug Metab. Dispos. (1991)
- Biosynthesis of menthofuran in Mentha x piperita: stereoselective and mechanistic studies. Fuchs, S., Zinn, S., Beck, T., Mosandl, A. J. Agric. Food Chem. (1999)
- Investigations of mechanisms of reactive metabolite formation from (R)-(+)-pulegone. Nelson, S.D., McClanahan, R.H., Thomassen, D., Gordon, W.P., Knebel, N. Xenobiotica (1992)
- Lack of histological cerebellar changes in Wistar rats given pulegone for 28 days. Comparison of immersion and perfusion tissue fixation. Mølck, A.M., Poulsen, M., Tindgard Lauridsen, S., Olsen, P. Toxicol. Lett. (1998)
- Metabolism of (R)-(+)-pulegone in F344 rats. Chen, L.J., Lebetkin, E.H., Burka, L.T. Drug Metab. Dispos. (2001)
- Analysis of pulegone and its enanthiomeric distribution in mint-flavoured food products. Siano, F., Catalfamo, M., Cautela, D., Servillo, L., Castaldo, D. Food additives and contaminants. (2005)
- Hepatotoxicity of pulegone in rats: its effects on microsomal enzymes, in vivo. Moorthy, B., Madyastha, P., Madyastha, K.M. Toxicology (1989)