Disease relevance of thulium

• This is the first preliminary study of a high-power Thulium fiber laser for fragmentation of urinary stones [1].
• In vivo animal studies are currently being planned for evaluation of the Thulium fiber laser for potential treatment of benign prostate hyperplasia (BPH) [2].
• In this pilot study, performing en bloc laryngeal cancer resection procedures was facilitated by use of the thulium laser [3].

High impact information on thulium

• Titration of the R-module with thulium indicated possible calcium binding sites in the loops formed by the nonarepeat sequences in the N-terminal part of the molecule and the importance of calcium binding for the stability of the R-module [4].
• We measured, with whole-scalp magnetoencephalography, evoked fields from 10 healthy subjects to 1-ms thulium-laser stimuli that selectively activated nociceptive nerve fibers [5].
• Assignment strategy for fast relaxing signals: complete aminoacid identification in thulium substituted calbindin D 9K [6].
• Thulium binding to the pancreatic beta-cell membrane [7].
• Radioactive thulium (171Tm) was used to probe cation-binding sites in the plasma membrane of beta-cell-rich pancreatic islets microdissected from noninbred ob/ob mice [7].

Biological context of thulium

• INTRODUCTION: The Thulium fiber laser may have several advantages over current urology lasers, including smaller size, more efficient operation, improved spatial beam quality, more precise tissue incision, and operation in pulsed or continuous-wave modes [2].
• Scalp topography of ultralate (C-fibres) evoked potentials following thulium YAG laser stimuli to tiny skin surface areas in humans [8].

Anatomical context of thulium

• STUDY DESIGN/MATERIALS AND METHODS: A continuous-wave, 110-W Thulium fiber laser operating at a wavelength of 1.91 microm, delivered 88.5+/-2.3 W of power through a 600-microm-core silica fiber for non-contact vaporization of canine prostates (n = 6) [2].
• MATERIALS AND METHODS: A 40 W thulium fiber laser operating at a wavelength of 1.94 microm delivered radiation in a continuous-wave or pulsed mode (10 msec) through either 300-microm- or 600-microm-core low-OH silica fibers for vaporization of canine prostate and incision of animal ureter and bladder-neck tissues [9].
• In an early exploration of a new technique for creating a patent nasolacrimal duct system, a chromium-sensitized and thulium- and holmium-doped YAG laser was used to canalize the nasolacrimal duct of a fresh-frozen bisected human cadaver head [10].

Associations of thulium with other chemical compounds

• METHODS: A thulium, holmium, chromium-doped:YAG (THC:YAG) crystal laser was used to create thermal sclerostomies in 49 glaucomatous eyes of 46 patients [11].
• Because these animals tolerated the shift reagent, thulium (III) 1,4,7,10-tetraazacyclododecane N,N',N",N"'-tetra(methylenephosphonate), nuclear magnetic resonance spectroscopy may prove valuable in monitoring intracellular cations in the liver after major injury [12].

Gene context of thulium

• Three hundred six-channel whole-scalp magnetoencephalographic (MEG) and midline EEG signals were recorded from nine healthy adults during painful thulium laser stimulation [13].
• METHODS: LEPs to thulium laser stimuli (3ms, 540 mJ, 5mm diameter) were recorded from 3 midline positions (Fz, Cz, Pz) in 20 patients with MS, and 6 patients with possible but unconfirmed MS [14].

Analytical, diagnostic and therapeutic context of thulium

• This paper describes the NMR structure of the R-module from AlgE4 and its titration with a substrate analogue and paramagnetic thulium ions [4].
• Ocular images were obtained using sodium chemical shift imaging (CSI) and 1,4,7,10-tetraazacyclododecane-N,N'N",N"'-tetramethylenephospho nate thulium (III) [Tm(DOTP)5-], a paramagnetic chemical shift reagent [15].
• A THC:YAG laser (thulium, holmium, chromium-doped YAG crystal) was used to create thermal sclerostomies in 21 glaucomatous eyes of 19 patients [16].
• Thulium fiber laser lithotripsy: an in vitro analysis of stone fragmentation using a modulated 110-watt Thulium fiber laser at 1.94 microm [1].
• High-power laser vaporization of the canine prostate using a 110 W Thulium fiber laser at 1.91 microm [2].

References