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Chemical Compound Review

AC1MHZDA     (2R,3S,5R,6S)-2- (hydroxymethyl)-6...

Synonyms: NSC 628324, 85618-21-9, Octylthioglucoside, N-Octyl-beta-D-thioglucoside, n-octyl-beta-D-thioglucopyranoside, ...
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Disease relevance of Octylthioglucoside


High impact information on Octylthioglucoside


Biological context of Octylthioglucoside


Anatomical context of Octylthioglucoside

  • The results allow us to conclude that the driving force for the formation of bR vesicles is the preferential incorporation of OTG molecules in the cytoplasmic side of the membrane (with possible preferential delipidation of the extracellular side), which creates spontaneous curvature of the purple membrane [4].
  • CMC's of octylthioglucoside and the peculiar bolaamphilphile dequalinium which concentrates in mitochondria are measured [9].

Associations of Octylthioglucoside with other chemical compounds

  • Heptylthioglucoside was as effective as octylthioglucoside and octylglucoside in solubilizing membrane proteins, and by the heptylthioglucoside-dilution procedure the H+-translocating ATPase (F1F0) and melibiose carrier could easily be reconstituted into liposomes [10].

Gene context of Octylthioglucoside


Analytical, diagnostic and therapeutic context of Octylthioglucoside


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  2. Thioglucosidase activity from Sphingobacterium sp. strain OTG1. Meulenbeld, G.H., Hartmans, S. Appl. Microbiol. Biotechnol. (2001) [Pubmed]
  3. Bacterial lipopolysaccharide copurifies with plasmid DNA: implications for animal models and human gene therapy. Wicks, I.P., Howell, M.L., Hancock, T., Kohsaka, H., Olee, T., Carson, D.A. Hum. Gene Ther. (1995) [Pubmed]
  4. Electron cryomicroscopy of bacteriorhodopsin vesicles: mechanism of vesicle formation. Denkov, N.D., Yoshimura, H., Kouyama, T., Walz, J., Nagayama, K. Biophys. J. (1998) [Pubmed]
  5. Characterization of a P-type copper-stimulated ATPase from mouse liver. Takeda, K., Ushimaru, M., Fukushima, Y., Kawamura, M. J. Membr. Biol. (1999) [Pubmed]
  6. Highly selective separation of rhodopsin from bovine rod outer segment membranes using combination of divalent cation and alkyl(thio)glucoside. Okada, T., Takeda, K., Kouyama, T. Photochem. Photobiol. (1998) [Pubmed]
  7. N omega-phosphoarginine phosphatase from rat renal microsome was alkaline phosphatase. Nishino, M., Tsujimura, S., Kuba, M., Kumon, A. Arch. Biochem. Biophys. (1994) [Pubmed]
  8. Purification and characterization of a high-affinity binding protein for pancreatic-type phospholipase A2. Hanasaki, K., Arita, H. Biochim. Biophys. Acta (1992) [Pubmed]
  9. Isothermic titration calorimetry to study CMCs of neutral surfactants and of the liposome-forming bolaamphiphile dequalinium. Lasch, J., Hildebrand, A. Journal of liposome research. (2002) [Pubmed]
  10. Value of heptyl-beta-D-thioglucoside, a new nonionic detergent, in studies on membrane proteins. Shimamoto, T., Saito, S., Tsuchiya, T. J. Biochem. (1985) [Pubmed]
  11. Properties of H(+)-ATPase from rat liver lysosomes as revealed by reconstitution into proteoliposomes. Okamoto, M., Hiratani, N., Arai, K., Ohkuma, S. J. Biochem. (1996) [Pubmed]
  12. Use of octyl beta-thioglucopyranoside in two-dimensional crystallization of membrane proteins. Chami, M., Pehau-Arnaudet, G., Lambert, O., Ranck, J.L., Lèvy, D., Rigaud, J.L. J. Struct. Biol. (2001) [Pubmed]
  13. Attempts to purify a second cellular receptor for a coxsackievirus B3 variant, CB3-RD from HeLa cells. Mohanty, J.G., Crowell, R.L. Virus Res. (1993) [Pubmed]
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