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Chemical Compound Review

hexylresorcinol     4-hexylbenzene-1,3-diol

Synonyms: Caprokol, Adrover, Ascaricid, Ascarinol, Ascaryl, ...
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Disease relevance of hexylresorcinol


High impact information on hexylresorcinol


Biological context of hexylresorcinol

  • Cytological and molecular analysis in the rare discoglossid species, Alytes muletensis (Sanchiz & Adrover 1977) and its bearing on archaeobatrachian phylogeny [8].
  • The IC50 values of hexylresorcinol and dodecylresorcinol were estimated as 1.24 and 1.15 microM for monophenolase and as 0.85 and 0.80 microM for diphenolase, respectively [9].
  • 4-Hexylresorcinol (4-HR) is used as an anthelmintic and antiseptic in human and veterinary medicine [10].

Anatomical context of hexylresorcinol


Associations of hexylresorcinol with other chemical compounds


Gene context of hexylresorcinol


Analytical, diagnostic and therapeutic context of hexylresorcinol


  1. Role of sulfites and 4-hexylresorcinol in microbial growth and melanosis prevention of deepwater pink shrimp (Parapenaeus longirostris) using a controlled atmosphere. Martínez-Alvarez, O., Gómez-Guillén, M.C., Montero, P. J. Food Prot. (2005) [Pubmed]
  2. Generally recognized as safe (GRAS) evaluation of 4-hexylresorcinol for use as a processing aid for prevention of melanosis in shrimp. Frankos, V.H., Schmitt, D.F., Haws, L.C., McEvily, A.J., Iyengar, R., Miller, S.A., Munro, I.C., Clydesdale, F.M., Forbes, A.L., Sauer, R.M. Regulatory toxicology and pharmacology : RTP. (1991) [Pubmed]
  3. Contact dermatitis to hexylresorcinol. Burrows, D., Irvine, J. Contact Derm. (1982) [Pubmed]
  4. Chronic diarrhea in returing travelers: intestinal parasitic infection with the fluke Metagonimus yokogawai. Goldsmith, R.S. South. Med. J. (1978) [Pubmed]
  5. Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes. Yen, G.C., Duh, P.D., Lin, C.W. Free Radic. Res. (2003) [Pubmed]
  6. Effect of complex formation between 4-hexylresorcinol and ethyl myristate on release rate of 4-hexylresorcinol from petrolatum base. Iga, K., Hussain, A., Kashihara, T. Journal of pharmaceutical sciences. (1981) [Pubmed]
  7. Polyphenol oxidases from latex of Hevea brasiliensis: purification and characterization. Wititsuwannakul, D., Chareonthiphakorn, N., Pace, M., Wititsuwannakul, R. Phytochemistry (2002) [Pubmed]
  8. Cytological and molecular analysis in the rare discoglossid species, Alytes muletensis (Sanchiz & Adrover 1977) and its bearing on archaeobatrachian phylogeny. Odierna, G., Andreone, F., Aprea, G., Arribas, O., Capriglione, T., Vences, M. Chromosome Res. (2000) [Pubmed]
  9. Inhibitory effects of hexylresorcinol and dodecylresorcinol on mushroom (Agaricus bisporus) tyrosinase. Chen, Q.X., Ke, L.N., Song, K.K., Huang, H., Liu, X.D. Protein J. (2004) [Pubmed]
  10. Inhibition of some spontaneous tumors by 4-hexylresorcinol in F344/N rats and B6C3F1 mice. Chhabra, R.S., Huff, J.E., Haseman, J., Hall, A., Baskin, G., Cowan, M. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1988) [Pubmed]
  11. 4-Hexylresorcinol as inhibitor of shrimp melanosis: efficacy and residues studies; evaluation of possible toxic effect in a human intestinal in vitro model (Caco-2); preliminary safety assessment. Guandalini, E., Ioppolo, A., Mantovani, A., Stacchini, P., Giovannini, C. Food additives and contaminants. (1998) [Pubmed]
  12. Oxidation of the flavonol quercetin by polyphenol oxidase. Jiménez, M., García-Carmona, F. J. Agric. Food Chem. (1999) [Pubmed]
  13. In vitro antiplaque effects of antiseptic phenols. Evans, R.T., Baker, P.J., Coburn, R.A., Fischman, S.L., Genco, R.J. J. Periodontol. (1977) [Pubmed]
  14. Influence of pH, benzoic acid, glutathione, EDTA, 4-hexylresorcinol, and sodium chloride on the pressure inactivation kinetics of mushroom polyphenol oxidase. Weemaes, C.A., Ludikhuyze, L.R., Van den Broeck, I., Hendrickx, M.E. J. Agric. Food Chem. (1999) [Pubmed]
  15. In vitro anthelmintic activity of Melia azedarach naturalized in Argentina. Szewczuk, V.D., Mongelli, E.R., Pomilio, A.B. Phytotherapy research : PTR. (2006) [Pubmed]
  16. Oxidation of the flavonol fisetin by polyphenol oxidase. Jiménez, M., Escribano-Cebrián, J., García-Carmona, F. Biochim. Biophys. Acta (1998) [Pubmed]
  17. Quantitative determination of hexylresorcinol in commercial antiseptic solution by high-pressure liquid chromatography. Musto, J.D., Sane, J.N., Warner, V.D. Journal of pharmaceutical sciences. (1979) [Pubmed]
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