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Chemical Compound Review:

AC1NQXEZ 2-(3,4-dihydroxyphenyl)-5,7- dihydroxy-3...

Synonyms: CHEMBL163316, SureCN380558, AG-D-94356, CHEBI:16860, ANW-53715, ...

Ko, W.C. et al., Dok-Go, H. et al., Marie, D. et al., De Souza, K.C. et al., Green, P.W. et al., et al.

Ko, Wang, Lei, Shih, Chung, Lin, Smolarz, Surdacka, Roliński,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Quercetin-3-methylether

We investigated the mechanisms of action of 3-O-methylquercetin (3-MQ), isolated from Rhamnus nakaharai (Hayata) Hayata (Rhamnaceae) which is used as a folk medicine for treating constipation, inflammation, tumors and asthma in Taiwan. The tension changes of tracheal segments were isometrically recorded on a polygraph [1].

High impact information on Quercetin-3-methylether

These results indicate that quercetin, (+)-dihydroquercetin, and quercetin 3-methyl ether are the active antioxidant principles in the fruits and stems of Opuntia ficus-indica var. saboten exhibiting neuroprotective actions against the oxidative injuries induced in cortical cell cultures [2].
Mechanisms of relaxant action of 3-O-methylquercetin in isolated guinea pig trachea [1].
Three of these were identified as isoquercitrin, quercetin, and quercetin-3-methyl ether, by comparing UV spectra and HPLC retention times with authentic standards [3].
Kaemferol-3-methyl ether (1), quercetin-3-methyl ether (2), kaemferol-3,7-dimethyl ether (3), 3-caffeoyl quinic acid (4) and 3,4-O-dicaffeoyl quinic acid (5) have been isolated for the first time from the leaves of Psiadia terebinthina A.J. Scott (Asteraceae) [4].
The influence of an ethyl acetate extract from Polygonum amphibium L. and quercetin-3-methyl ether isolated from them were examined on the human immune system [5].

Associations of Quercetin-3-methylether with other chemical compounds

The flavonoids quercetin, 3-O-methylquercetin and luteolin play an important role in the anti-inflammatory activity of Achyrocline satureioides ethanol extracts when administered intraperitoneally [6].

References

Mechanisms of relaxant action of 3-O-methylquercetin in isolated guinea pig trachea. Ko, W.C., Wang, H.L., Lei, C.B., Shih, C.H., Chung, M.I., Lin, C.N. Planta Med. (2002) [Pubmed]
Neuroprotective effects of antioxidative flavonoids, quercetin, (+)-dihydroquercetin and quercetin 3-methyl ether, isolated from Opuntia ficus-indica var. saboten. Dok-Go, H., Lee, K.H., Kim, H.J., Lee, E.H., Lee, J., Song, Y.S., Lee, Y.H., Jin, C., Lee, Y.S., Cho, J. Brain Res. (2003) [Pubmed]
Phenolic compounds on the pod-surface of pigeonpea, Cajanus cajan, mediate feeding behavior of Helicoverpa armigera larvae. Green, P.W., Stevenson, P.C., Simmonds, M.S., Sharma, H.C. J. Chem. Ecol. (2003) [Pubmed]
Constituents of Psiadia terebinthina A.J. Scott, an endemic Asteraceae from Mauritius. Marie, D., Gurib-Fakim, A., Gray, A., Waterman, P. Nat. Prod. Res. (2006) [Pubmed]
Influence of ethyl acetate extract and quercetin-3-methyl ether from Polygonum amphibium on activation lymphocytes from peripheral blood of healthy donor in vitro. Smolarz, H.D., Surdacka, A., Roliński, J. Phytotherapy research : PTR. (2003) [Pubmed]
Influence of excipients and technological process on anti-inflammatory activity of quercetin and Achyrocline satureioides (Lam.) D.C. extracts by oral route. De Souza, K.C., Bassani, V.L., Schapoval, E.E. Phytomedicine (2007) [Pubmed]

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