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Chemical Compound Review

Entacone     ethyl(2E,4E)-3,7,11- trimethyldodeca-2,4...

Synonyms: Altozar, Gencor, Hydroprene, Altozar IGR, AC1NSYDZ, ...
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Disease relevance of Altozar


Psychiatry related information on Altozar


High impact information on Altozar


Biological context of Altozar

  • Altozar treatments on the fifth day of feeding, shortly before oviposition, and especially immediately after detachment (points 4, 5 and 6, respectively) mainly resulted in non-viability of the eggs [8].
  • Hydroprene had a considerable effect on the morphogenesis of external genitalia of the oriental cockroach, Blatta orientalis L [3].

Anatomical context of Altozar

  • Exposure of nymphs to hydroprene resulted in abnormal adultoids with structural and positional distortions, and reduced or absent cuticular sclerotizations of the external genitalia [3].
  • A high correlation between wrinkled wings and malformed male genitalia can be an important criterion to evaluate the effects of hydroprene on this species [3].
  • In males, the epithelial cells of wings, serrata of the right phallomere, titillator and other lobes of the left phallomere were sensitive to hydroprene [3].

Associations of Altozar with other chemical compounds

  • Ixodes persulcatus females were treated with Altozar and DDT at one of six consecutive time-points during the period beginning with attachment and ending with the commencement of oviposition [8].
  • The sensitive developmental period of last-instar German cockroaches, Blattella germanica (L.), to topical applications (10 micrograms/microliters) of fenoxycarb and hydroprene was determined [9].

Gene context of Altozar

  • Cockroaches treated with 100 micrograms/microliters of hydroprene lived 10-14 wk fewer than control adults and often attempted a sixth (supernumerary) molt [1].

Analytical, diagnostic and therapeutic context of Altozar


  1. Comparative activity of fenoxycarb and hydroprene in sterilizing the German cockroach (Dictyoptera: Blattellidae). King, J.E., Bennett, G.W. J. Econ. Entomol. (1989) [Pubmed]
  2. Toxicological efficacy of some indigenous dill compounds against the flesh fly, Parasarcophaga dux Thomson. Khalaf, A.F. Journal of the Egyptian Society of Parasitology. (2004) [Pubmed]
  3. Morphogenetic effects of hydroprene on genitalia of the oriental cockroach (Dictyoptera: Blattidae). Bao, N.G., Robinson, W.H. J. Econ. Entomol. (1990) [Pubmed]
  4. Assay and identification of juvenile hormone binding proteins in Leucophaea maderae. Kovalick, G.E., Koeppe, J.K. Mol. Cell. Endocrinol. (1983) [Pubmed]
  5. Methoprene and hydroprene are metabolized by ester cleavage in isolated hepatocytes. Morello, A., Repetto, Y., Agosin, M. Drug Metab. Dispos. (1980) [Pubmed]
  6. cDNA cloning and expression of a hormone-regulated heat shock protein (hsc 70) from the prothoracic gland of Manduca sexta. Rybczynski, R., Gilbert, L.I. Insect Biochem. Mol. Biol. (2000) [Pubmed]
  7. Activity of novel juvenoids on arthropods of veterinary importance. Londershausen, M., Alig, B., Pospischil, R., Turberg, A. Arch. Insect Biochem. Physiol. (1996) [Pubmed]
  8. Comparison of the effects of Altozar and DDT on females of Ixodes persulcatus Sch. during and after feeding. Joffe, I.D., Uspenskiy, I.V. Exp. Appl. Acarol. (1985) [Pubmed]
  9. Sensitive developmental period of last-instar German cockroaches (Dictyoptera: Blattelidae) to fenoxycarb and hydroprene. King, J.E., Bennett, G.W. J. Med. Entomol. (1991) [Pubmed]
  10. Population growth of Dermatophagoides farinae Hughes (Acari: Epidermoptidae) suppressed by methoprene and hydroprene. Downing, A.S., Wright, C.G., Farrier, M.H. J. Med. Entomol. (1993) [Pubmed]
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