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MeSH Review

Genitalia, Male

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Disease relevance of Genitalia, Male


Psychiatry related information on Genitalia, Male

  • This proliferative phase, which begins on embryonic day 17 (E17), is induced by the interaction of a few specific neurons in the sex ganglia with a peripheral target, the male genitalia, during a critical period that extends from E13 to E16 [5].

High impact information on Genitalia, Male


Biological context of Genitalia, Male

  • The retention of Müllerian structures and undervirilization of male genitalia in these cases could be the result of failure in production of adequate amounts of testosterone and Müllerian inhibitory factor at appropriate times in gestation [11].

Anatomical context of Genitalia, Male


Associations of Genitalia, Male with chemical compounds


Gene context of Genitalia, Male


Analytical, diagnostic and therapeutic context of Genitalia, Male


  1. Primary lymphedema of the genitalia in children and adolescents. Ross, J.H., Kay, R., Yetman, R.J., Angermeier, K. J. Urol. (1998) [Pubmed]
  2. Molecular and clinical studies of three cases of female pseudohermaphroditism with caudal dysplasia suggest multiple etiologies. Erickson, R.P., Stone, J.F., McNoe, L.A., Eccles, M.R. Clin. Genet. (1997) [Pubmed]
  3. Oestrogen formation in genital and non-genital skin fibroblasts cultured from patients with hypospadias. Staib, P., Kau, N., Romalo, G., Schweikert, H.U. Clin. Endocrinol. (Oxf) (1994) [Pubmed]
  4. Contact dermatitis of the male genitalia due to latex gloves. Herod, E.L. General dentistry. (1990) [Pubmed]
  5. Cell proliferation in a peripheral target is required for the induction of central neurogenesis in the leech. Becker, T.S., Bothe, G., Harley, A.R., Macagno, E.R. J. Neurobiol. (1998) [Pubmed]
  6. Caudal is the Hox gene that specifies the most posterior Drosophile segment. Moreno, E., Morata, G. Nature (1999) [Pubmed]
  7. Expression of lipocalin-type prostaglandin D synthase (beta-trace) in human heart and its accumulation in the coronary circulation of angina patients. Eguchi, Y., Eguchi, N., Oda, H., Seiki, K., Kijima, Y., Matsu-ura, Y., Urade, Y., Hayaishi, O. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  8. Prostaglandin D synthase: structure and function. Urade, Y., Hayaishi, O. Vitam. Horm. (2000) [Pubmed]
  9. A Drosophila melanogaster mutant resistant to a chemical analog of juvenile hormone. Wilson, T.G., Fabian, J. Dev. Biol. (1986) [Pubmed]
  10. Immunohistochemical localization of microsomal PGE synthase-1 and cyclooxygenases in male mouse reproductive organs. Lazarus, M., Munday, C.J., Eguchi, N., Matsumoto, S., Killian, G.J., Kubata, B.K., Urade, Y. Endocrinology (2002) [Pubmed]
  11. Double vagina, cardiac, pulmonary, and other genital malformations with 46,XY karyotype. Meacham, L.R., Winn, K.J., Culler, F.L., Parks, J.S. Am. J. Med. Genet. (1991) [Pubmed]
  12. Influence of androgens and age on androgen receptor and 5 alpha-reductase II transcription. Hellwinkel, O.J., Müller, A., Struve, D., Hiort, O. Eur. J. Endocrinol. (2000) [Pubmed]
  13. Genetic mechanisms of fetal male undermasculinization: a background to the role of endocrine disruptors. Hughes, I.A., Martin, H., Jääskeläinen, J. Environmental research. (2006) [Pubmed]
  14. Sexual differentiation. Sinisi, A.A., Pasquali, D., Notaro, A., Bellastella, A. J. Endocrinol. Invest. (2003) [Pubmed]
  15. Natural mutagenesis study of the human steroid 5 alpha-reductase 2 isozyme. Wigley, W.C., Prihoda, J.S., Mowszowicz, I., Mendonca, B.B., New, M.I., Wilson, J.D., Russell, D.W. Biochemistry (1994) [Pubmed]
  16. Maternal serum level of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene and risk of cryptorchidism, hypospadias, and polythelia among male offspring. Longnecker, M.P., Klebanoff, M.A., Brock, J.W., Zhou, H., Gray, K.A., Needham, L.L., Wilcox, A.J. Am. J. Epidemiol. (2002) [Pubmed]
  17. Effect of prenatal estrogen exposure on male genitalia. Mills, J.L., Bongiovanni, A.M. Pediatrics (1978) [Pubmed]
  18. New frameshift mutation in the 5alpha-reductase type 2 gene in a Brazilian patient with 5alpha-reductase deficiency. Ferraz, L.F., Mathias Baptista, M.T., Maciel-Guerra, A.T., Júnior, G.G., Hackel, C. Am. J. Med. Genet. (1999) [Pubmed]
  19. Sex differences in interest in infants in juvenile rhesus monkeys: relationship to prenatal androgen. Herman, R.A., Measday, M.A., Wallen, K. Hormones and behavior. (2003) [Pubmed]
  20. Characterization of MTM1 mutations in 31 Japanese families with myotubular myopathy, including a patient carrying 240 kb deletion in Xq28 without male hypogenitalism. Tsai, T.C., Horinouchi, H., Noguchi, S., Minami, N., Murayama, K., Hayashi, Y.K., Nonaka, I., Nishino, I. Neuromuscul. Disord. (2005) [Pubmed]
  21. Natural variation and copulatory plug formation in Caenorhabditis elegans. Hodgkin, J., Doniach, T. Genetics (1997) [Pubmed]
  22. Effects of castration on the expression of brain-derived neurotrophic factor (BDNF) in the vas deferens and male accessory genital glands of the rat. Mirabella, N., Squillacioti, C., Paone, I., Ciarcia, R., Russo, M., Paino, G. Cell Tissue Res. (2006) [Pubmed]
  23. Male pseudohermaphroditism resulting from a novel mutation in the human steroid 5 alpha-reductase type 2 gene (SRD5A2). Anwar, R., Gilbey, S.G., New, J.P., Markham, A.F. MP, Mol. Pathol. (1997) [Pubmed]
  24. Fetal Leydig cells: cellular origin, morphology, life span, and special functional features. Huhtaniemi, I., Pelliniemi, L.J. Proc. Soc. Exp. Biol. Med. (1992) [Pubmed]
  25. Physical examination. Part 14. Male genitalia. Alexander, M.M., Brown, M.S. Nursing. (1976) [Pubmed]
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