Disease relevance of trifluoroborane

• Inhalation toxicity studies with boron trifluoride [1].

Psychiatry related information on trifluoroborane

• The group is easily introduced under mild conditions, over short reaction times, and in the presence of a wide variety of other protecting groups by the reaction of the 4,6-diol with triethyl (2-iodophenyl)orthoacetate and camphorsulfonic acid, followed by trimethylsilyl cyanide and boron trifluoride etherate [2].

High impact information on trifluoroborane

• For the purpose of retaining D/L-amino acid configuration in sequencing, we used an aprotic acid, i.e., the Lewis acid boron trifluoride (BF3), for the cyclization/cleavage reaction [3].
• METHODS: The fatty acid composition of cell lipids was determined by gas chromatography after transesterification in the presence of boron trifluoride and methanol [4].
• Precolumn derivatization of pipemidic acid was achieved by a methylation reaction with boron trifluoride in methanol after extraction from plasma with chloroform containing 4% ethanol [5].
• The mechanisms for the uncatalyzed and boron trifluoride (BF3) assisted Baeyer-Villiger reactions between acetone and hydrogen peroxide have been investigated using high level ab initio [MP2 and CCSD(T)] and density functional theory (B3LYP) methods [6].
• Standard procedures were used for the preparation of the educts and the glyco lipids: trichloracetimidate procedure for the preparation of long-chained compounds, glycosylation using the beta-peracetate and boron trifluoride etherate was successful for the preparation of lipids with a medium-alkyl chain length [7].

Biological context of trifluoroborane

• Esterification of free fatty acids and transesterification of phospholipid linked fatty acids were achieved with 14% boron trifluoride in methanol (BF3-CH3OH) in 20 s and 50 s, respectively, under low power microwave irradiation (60 W) with a post-reaction cooling of less than 5 min [8].

Anatomical context of trifluoroborane

• Assay of lipids in dog myocardium using capillary gas chromatography and derivatization with boron trifluoride and methanol [9].

Associations of trifluoroborane with other chemical compounds

• The cyclization proceeded when boron trifluoride diethyl etherate was used as an additive reagent, thus giving rise to the corresponding cyclized products (7a) and (7b) in moderate yields [10].
• The positions of linkage in the D-mannans derived from Saccharomyces cerevisiae X2180 and its mutants, mnn1, mnn2, and mnn4, were established by perethylation and subsequent reductive cleavage with triethylsilane in the presence of boron trifluoride etherate (BF3 . Et2O) or trimethylsilyl trifluoromethanesulfonate [11].
• Treatment of the acyl-protected pMP glycosides with thiophenol and boron trifluoride etherate gave the corresponding thioglycosides in 80-100% yield and high (> 20:1) beta/alpha selectivity [12].

Gene context of trifluoroborane

• An acute study of boron trifluoride (BF3) in rats indicated the 4-hr LC50 to be 1.21 mg/liter [1].
• D-homo-steroids. Part V. A study of the mechanism of d-Homoannulation of 17alpha-hydroxypregnan-20-ones with boron trifluoride [13].

Analytical, diagnostic and therapeutic context of trifluoroborane

• 1. Treatment of cellulose acetate gel strips by boron trifluoride in methanol has been shown previously to produce a material suitable for isoelectric focusing [14].

References