Disease relevance of Indopol

• Polybutylene, a low-energy surface (41.2 mJ.m-2), followed by stainless steel (65.7 mJ.m-2), was most colonized by Aeromonas cells, whereas few cells were observed on copper, which has a surface energy of 45.8 mJ.m-2 [1].
• The gaseous microemboli (GME) production and gas transfer characteristics of two series of bubble oxygenators (Harvey H-1500 and Bentley BOS-10) were evaluated during clinical perfusion in 33 adult patients during open heart surgery for acquired valvular and ischaemic heart disease [2].

High impact information on Indopol

• Surface tension and adsorption properties of PEO/polypropylene oxide(PPO) and PEO/polybutylene oxide(PBO) block copolymer surfactants on a hydrophobic surface (low density polyethylene, LDPE) were investigated, using the Wilhelmy plate surface tension technique and x-ray photoelectron spectroscopy(XPS) [3].
• This study describes a critical size defect in the goal and the evaluation of three bone fillers (particulate autograft, particulate allograft, and a polyethylene oxide/polybutylene terephthalate copolymer) in this defect [4].
• PEGT/PBT (polyethylene glycol terephthalate/polybutylene terephthalate) copolymer matrices with three different surface coatings [calcium-phosphate (Ca-P), collagen, and gas plasma] were placed into dorsal skinfold chambers of 24 balb/c mice [5].
• The lower gas:blood flow ratios for the BOS-10 oxygenators in group C resulted in significantly higher PaCO2 values well outside the physiological range (4 to 6 kPa at 37 degrees C) during the rewarming phase (mean PaCO2 = 7.6 +/- 0.8 kPa) of cardiopulmonary bypass than did the H-1500 oxygenator (mean PaCO2 = 6.3 +/- 0.7 kPa) [2].
• This paper reports our clinical experience with five "hard shell" bubble oxygenators--Harvey H 1500, Harvey H 1000, Shiley S100A, Cobe Optiflo II and Bentley BOS 10 [6].

Associations of Indopol with other chemical compounds

• Porous structures have been prepared from several relevant polymers in the biomedical and tissue-engineering field: poly(D,L-lactide) (PDLLA), 1000PEOT70PBT30, a segmented poly(ether ester) based on polyethylene oxide and polybutylene terephthalate, and poly(epsilon-caprolactone) (PCL) [7].

Analytical, diagnostic and therapeutic context of Indopol

• Extracellular materials could also be observed on polybutylene surfaces, especially after 1 and 4 h of exposure at the refrigeration temperature [1].
• Scanning electron microscopy observation was used to investigate the ability of Aeromonas hydrophila to attach to various water distribution pipe surfaces, such as stainless steel, copper, and polybutylene, after different contact times at ambient and storage temperatures [1].
• The Bentley BOS-10 oxygenator used a lower gas:blood flow ratio to achieve physiological levels (range 9 to 13 kPa at 37 degrees C) of PaO2 than did the Harvey H-1500 oxygenator, but there was no difference in the number of GME detected [2].
• After heparinization for cardiopulmonary bypass, activated clotting time was 462 s (median) in group H, 1500 s in group P, and 727 s in group C (P < 0.003 vs. groups H and P) [8].

References