Chemical Compound Review:
Dihydrothymine 5-methyl-1,3-diazinane-2,4- dione
Synonyms:
SureCN48294, AGN-PC-00BJBU, AG-G-71145, CHEBI:27468, HMDB00079, ...
- Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions. Ide, H., Petrullo, L.A., Hatahet, Z., Wallace, S.S. J. Biol. Chem. (1991)
- Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. Hernández, A.I., Balzarini, J., Karlsson, A., Camarasa, M.J., Pérez-Pérez, M.J. J. Med. Chem. (2002)
- Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia coli Nth and Fpg proteins. David-Cordonnier, M.H., Laval, J., O'Neill, P. J. Biol. Chem. (2000)
- PYD2 encodes 5,6-dihydropyrimidine amidohydrolase, which participates in a novel fungal catabolic pathway. Gojkovic, Z., Jahnke, K., Schnackerz, K.D., Piskur, J. J. Mol. Biol. (2000)
- The action of Escherichia coli endonuclease III on multiply damaged sites in DNA. Chaudhry, M.A., Weinfeld, M. J. Mol. Biol. (1995)
- Contributions of an endonuclease IV homologue to DNA repair in the African swine fever virus. Lamarche, B.J., Tsai, M.D. Biochemistry (2006)
- Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease. David-Cordonnier, M.H., Cunniffe, S.M., Hickson, I.D., O'Neill, P. Biochemistry (2002)
- Characterization of antibodies to dihydrothymine, a radiolysis product of DNA. Hubbard, K., Ide, H., Erlanger, B.F., Wallace, S.S. Biochemistry (1989)
- Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects. D'Ham, C., Romieu, A., Jaquinod, M., Gasparutto, D., Cadet, J. Biochemistry (1999)
- Thymine ring saturation and fragmentation products: lesion bypass, misinsertion and implications for mutagenesis. Evans, J., Maccabee, M., Hatahet, Z., Courcelle, J., Bockrath, R., Ide, H., Wallace, S. Mutat. Res. (1993)
- Absence of pyrimidine salvage and prevention of thymineless radiosensitization in Escherichia coli thyA cells fed dihydrothymine or thymine glycol. Claycamp, H.G., Smith, S.T. Radiat. Res. (1988)
- Purification and characterization of an ATP-dependent amidohydrolase, N-methylhydantoin amidohydrolase, from Pseudomonas putida 77. Ogawa, J., Kim, J.M., Nirdnoy, W., Amano, Y., Yamada, H., Shimizu, S. Eur. J. Biochem. (1995)
- Identification and tissue-specific expression of a NADH-dependent activity of dihydropyrimidine dehydrogenase in man. Van Kuilenburg, A.B., Van Lenthe, H., Van Gennip, A.H. Anticancer Res. (1996)
- Efficiency of excision of 8-oxo-guanine within DNA clustered damage by XRS5 nuclear extracts and purified human OGG1 protein. David-Cordonnier, M.H., Boiteux, S., O'Neill, P. Biochemistry (2001)
- Ab initio theoretical study of the structures of thymine glycol and dihydrothymine. Miaskiewicz, K., Miller, J., Osman, R. Int. J. Radiat. Biol. (1993)
- E.s.r. and spin-trapping studies of dihydropyrimidines. gamma-Radiolysis in the polycrystalline state and U.V. photolysis in aqueous solution. Mossoba, M.M., Rosenthal, I., Riesz, P. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. (1981)
- Excision of 8-oxoguanine within clustered damage by the yeast OGG1 protein. David-Cordonnier, M.H., Boiteux, S., O'Neill, P. Nucleic Acids Res. (2001)
- Comparison of substrate specificities of Escherichia coli endonuclease III and its mouse homologue (mNTH1) using defined oligonucleotide substrates. Asagoshi, K., Odawara, H., Nakano, H., Miyano, T., Terato, H., Ohyama, Y., Seki, S., Ide, H. Biochemistry (2000)
- Degradation of pyrimidine bases in Clostridium sticklandii. Schäfer, R., Schwartz, A.C. Arch. Microbiol. (1980)
- Gas chromatography-mass spectrometry with high-performance liquid chromatography prepurification for monitoring the endonuclease III-mediated excision of 5-hydroxy-5,6-dihydrothymine and 5,6-dihydrothymine from gamma-irradiated DNA. D'Ham, C., Ravanat, J.L., Cadet, J. J. Chromatogr. B Biomed. Sci. Appl. (1998)