Gene Review:
HCST - hematopoietic cell signal transducer
Homo sapiens
Synonyms:
DAP10, DKFZP586C1522, DNAX-activation protein 10, Hematopoietic cell signal transducer, KAP10, ...
- An activating immunoreceptor complex formed by NKG2D and DAP10. Wu, J., Song, Y., Bakker, A.B., Bauer, S., Spies, T., Lanier, L.L., Phillips, J.H. Science (1999)
- NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. Upshaw, J.L., Arneson, L.N., Schoon, R.A., Dick, C.J., Billadeau, D.D., Leibson, P.J. Nat. Immunol. (2006)
- DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells. Wu, J., Cherwinski, H., Spies, T., Phillips, J.H., Lanier, L.L. J. Exp. Med. (2000)
- Cutting edge: KAP10, a novel transmembrane adapter protein genetically linked to DAP12 but with unique signaling properties. Chang, C., Dietrich, J., Harpur, A.G., Lindquist, J.A., Haude, A., Loke, Y.W., King, A., Colonna, M., Trowsdale, J., Wilson, M.J. J. Immunol. (1999)
- Molecular cloning and characterization of pig immunoreceptor DAP10 and NKG2D. Yim, D., Jie, H.B., Sotiriadis, J., Kim, Y.S., Kim, K.S., Rothschild, M.F., Lanier, L.L., Kim, Y.B. Immunogenetics (2001)
- Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells. Karimi, M., Cao, T.M., Baker, J.A., Verneris, M.R., Soares, L., Negrin, R.S. J. Immunol. (2005)
- Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics. Graham, D.B., Cella, M., Giurisato, E., Fujikawa, K., Miletic, A.V., Kloeppel, T., Brim, K., Takai, T., Shaw, A.S., Colonna, M., Swat, W. J. Immunol. (2006)
- Downward movement of cadmium and phosphorus from phosphatic fertilisers in a pasture soil in New Zealand. Loganathan, P., Hedley, M.J. Environ. Pollut. (1997)
- Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells. Borrego, F., Kabat, J., Kim, D.K., Lieto, L., Maasho, K., Peña, J., Solana, R., Coligan, J.E. Mol. Immunol. (2002)
- Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21. Rogers, M.A., Langbein, L., Winter, H., Beckmann, I., Praetzel, S., Schweizer, J. J. Invest. Dermatol. (2004)