Gene Review:
ADAP1 - ArfGAP with dual PH domains 1
Homo sapiens
Synonyms:
Arf-GAP with dual PH domain-containing protein 1, CENTA1, Centaurin-alpha-1, Cnt-a1, GCS1L, ...
- Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins. Hanck, T., Stricker, R., Sedehizade, F., Reiser, G. J. Neurochem. (2004)
- Neurons and plaques of Alzheimer's disease patients highly express the neuronal membrane docking protein p42IP4/centaurin alpha. Reiser, G., Bernstein, H.G. Neuroreport (2002)
- Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins. Dubois, T., Kerai, P., Zemlickova, E., Howell, S., Jackson, T.R., Venkateswarlu, K., Cullen, P.J., Theibert, A.B., Larose, L., Roach, P.J., Aitken, A. J. Biol. Chem. (2001)
- Identification and cloning of centaurin-alpha. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain. Hammonds-Odie, L.P., Jackson, T.R., Profit, A.A., Blader, I.J., Turck, C.W., Prestwich, G.D., Theibert, A.B. J. Biol. Chem. (1996)
- Centaurin-alpha 1, an ADP-ribosylation factor 6 GTPase activating protein, inhibits beta 2-adrenoceptor internalization. Lawrence, J., Mundell, S.J., Yun, H., Kelly, E., Venkateswarlu, K. Mol. Pharmacol. (2005)
- Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1. Venkateswarlu, K., Oatey, P.B., Tavaré, J.M., Jackson, T.R., Cullen, P.J. Biochem. J. (1999)
- Cellular expression and subcellular localization of the human Ins(1,3,4,5)P(4)-binding protein, p42(IP4), in human brain and in neuronal cells. Sedehizade, F., Hanck, T., Stricker, R., Horstmayer, A., Bernstein, H.G., Reiser, G. Brain Res. Mol. Brain Res. (2002)
- In vitro evaluation of CENTA, a new beta-lactamase-susceptible chromogenic cephalosporin reagent. Jones, R.N., Wilson, H.W., Novick, W.J., Barry, A.L., Thornsberry, C. J. Clin. Microbiol. (1982)
- The arf6 GAP centaurin alpha-1 is a neuronal actin-binding protein which also functions via GAP-independent activity to regulate the actin cytoskeleton. Thacker, E., Kearns, B., Chapman, C., Hammond, J., Howell, A., Theibert, A. Eur. J. Cell Biol. (2004)
- Centaurin-alpha 1 associates in vitro and in vivo with nucleolin. Dubois, T., Zemlickova, E., Howell, S., Aitken, A. Biochem. Biophys. Res. Commun. (2003)
- Molecular cloning and functional characterization of a human homologue of centaurin-alpha. Venkateswarlu, K., Cullen, P.J. Biochem. Biophys. Res. Commun. (1999)
- Interaction of the brain-specific protein p42IP4/centaurin-alpha1 with the peptidase nardilysin is regulated by the cognate ligands of p42IP4, PtdIns(3,4,5)P3 and Ins(1,3,4,5)P4, with stereospecificity. Stricker, R., Chow, K.M., Walther, D., Hanck, T., Hersh, L.B., Reiser, G. J. Neurochem. (2006)