Gene Review:
WWP1 - WW domain containing E3 ubiquitin protein...
Homo sapiens
Synonyms:
AIP5, Atrophin-1-interacting protein 5, DKFZP434D2111, NEDD4-like E3 ubiquitin-protein ligase WWP1, TGIF-interacting ubiquitin ligase 1, ...
- HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway. Martin-Serrano, J., Eastman, S.W., Chung, W., Bieniasz, P.D. J. Cell Biol. (2005)
- Late assembly motifs of human T-cell leukemia virus type 1 and their relative roles in particle release. Heidecker, G., Lloyd, P.A., Fox, K., Nagashima, K., Derse, D. J. Virol. (2004)
- WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. Bednarek, A.K., Laflin, K.J., Daniel, R.L., Liao, Q., Hawkins, K.A., Aldaz, C.M. Cancer Res. (2000)
- Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer. Chen, C., Sun, X., Guo, P., Dong, X.Y., Sethi, P., Zhou, W., Zhou, Z., Petros, J., Frierson, H.F., Vessella, R.L., Atfi, A., Dong, J.T. Oncogene (2007)
- Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells. Chen, C., Sun, X., Guo, P., Dong, X.Y., Sethi, P., Cheng, X., Zhou, J., Ling, J., Simons, J.W., Lingrel, J.B., Dong, J.T. J. Biol. Chem. (2005)
- A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis. Huang, K., Johnson, K.D., Petcherski, A.G., Vandergon, T., Mosser, E.A., Copeland, N.G., Jenkins, N.A., Kimble, J., Bresnick, E.H. Gene (2000)
- Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein. Flasza, M., Gorman, P., Roylance, R., Canfield, A.E., Baron, M. Biochem. Biophys. Res. Commun. (2002)
- PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction. Jin, C., Ge, L., Ding, X., Chen, Y., Zhu, H., Ward, T., Wu, F., Cao, X., Wang, Q., Yao, X. Biochem. Biophys. Res. Commun. (2006)
- Regulation of the nuclear localization of the human Nedd4-related WWP1 protein by Notch. Flasza, M., Nguyen Huu, N.S., Mazaleyrat, S., Clémence, S., Villemant, C., Clarke, R., Baron, M. Mol. Membr. Biol. (2006)
- Differential expression and localisation of WWP1, a Nedd4-like protein, in epithelia. Malbert-Colas, L., Fay, M., Cluzeaud, F., Blot-Chabaud, M., Farman, N., Dhermy, D., Lecomte, M.C. Pflugers Arch. (2003)
- WWP1-dependent ubiquitination and degradation of the lung Krüppel-like factor, KLF2. Zhang, X., Srinivasan, S.V., Lingrel, J.B. Biochem. Biophys. Res. Commun. (2004)
- Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1). Komuro, A., Imamura, T., Saitoh, M., Yoshida, Y., Yamori, T., Miyazono, K., Miyazawa, K. Oncogene (2004)
- Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases. Galinier, R., Gout, E., Lortat-Jacob, H., Wood, J., Chroboczek, J. Biochemistry (2002)
- Lung Krüppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase. Conkright, M.D., Wani, M.A., Lingrel, J.B. J. Biol. Chem. (2001)
- PCIF1, a novel human WW domain-containing protein, interacts with the phosphorylated RNA polymerase II. Fan, H., Sakuraba, K., Komuro, A., Kato, S., Harada, F., Hirose, Y. Biochem. Biophys. Res. Commun. (2003)
- Characterization of KIBRA, a novel WW domain-containing protein. Kremerskothen, J., Plaas, C., Büther, K., Finger, I., Veltel, S., Matanis, T., Liedtke, T., Barnekow, A. Biochem. Biophys. Res. Commun. (2003)
- Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase. Verdecia, M.A., Joazeiro, C.A., Wells, N.J., Ferrer, J.L., Bowman, M.E., Hunter, T., Noel, J.P. Mol. Cell (2003)