Gene Review:
TMC1 - transmembrane channel-like 1
Homo sapiens
Synonyms:
DFNA36, DFNB11, DFNB7, Transmembrane channel-like protein 1, Transmembrane cochlear-expressed protein 1
- Beethoven, a mouse model for dominant, progressive hearing loss DFNA36. Vreugde, S., Erven, A., Kros, C.J., Marcotti, W., Fuchs, H., Kurima, K., Wilcox, E.R., Friedman, T.B., Griffith, A.J., Balling, R., Hrabé De Angelis, M., Avraham, K.B., Steel, K.P. Nat. Genet. (2002)
- TMC-1 A, B, C and D, new antibiotics of the manumycin group produced by Streptomyces sp. Taxonomy, production, isolation, physico-chemical properties, structure elucidation and biological properties. Kohno, J., Nishio, M., Kawano, K., Nakanishi, N., Suzuki, S., Uchida, T., Komatsubara, S. J. Antibiot. (1996)
- Establishment and characterization of a human gastric carcinoma cell line TMC-1. Shyu, R.Y., Jiang, S.Y., Jong, Y.J., Cheng, K.C., Lin, C.H., Yu, J.C., Wu, M.F., Chang, T.M. Cells Tissues Organs (Print) (2004)
- Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function. Kurima, K., Peters, L.M., Yang, Y., Riazuddin, S., Ahmed, Z.M., Naz, S., Arnaud, D., Drury, S., Mo, J., Makishima, T., Ghosh, M., Menon, P.S., Deshmukh, D., Oddoux, C., Ostrer, H., Khan, S., Riazuddin, S., Deininger, P.L., Hampton, L.L., Sullivan, S.L., Battey, J.F., Keats, B.J., Wilcox, E.R., Friedman, T.B., Griffith, A.J. Nat. Genet. (2002)
- Construction of P1-derived artificial chromosome and yeast artificial chromosome contigs encompassing the DFNB7 and DFNB11 region of chromosome 9q13-21. Greinwald, J.H., Scott, D.A., Marietta, J.R., Carmi, R., Manaligod, J., Ramesh, A., Zbar, R.I., Kraft, M.L., Elbedour, K., Yairi, Y., Musy, M., Skvorak, A.B., Van Camp, G., Srisailapathy, C.R., Lovett, M., Morton, C.C., Sheffield, V.C., Smith, R.J. Genome Res. (1997)
- First astronomical detection of the cumulene carbon chain molecule H2C6 in TMC-1. Langer, W.D., Velusamy, T., Kuiper, T.B., Peng, R., McCarthy, M.C., Travers, M.J., Kovacs, A., Gottlieb, C.A., Thaddeus, P. Astrophys. J. (1997)
- Novel sequence variants in the TMC1 gene in Pakistani families with autosomal recessive hearing impairment. Santos, R.L., Wajid, M., Khan, M.N., McArthur, N., Pham, T.L., Bhatti, A., Lee, K., Irshad, S., Mir, A., Yan, K., Chahrour, M.H., Ansar, M., Ahmad, W., Leal, S.M. Hum. Mutat. (2005)
- Novel TMC1 structural and splice variants associated with congenital nonsyndromic deafness in a Sudanese pedigree. Meyer, C.G., Gasmelseed, N.M., Mergani, A., Magzoub, M.M., Muntau, B., Thye, T., Horstmann, R.D. Hum. Mutat. (2005)
- Multiple quantitative trait loci modify cochlear hair cell degeneration in the Beethoven (Tmc1Bth) mouse model of progressive hearing loss DFNA36. Noguchi, Y., Kurima, K., Makishima, T., de Angelis, M.H., Fuchs, H., Frolenkov, G., Kitamura, K., Griffith, A.J. Genetics (2006)
- A novel mutation at the DFNA36 hearing loss locus reveals a critical function and potential genotype-phenotype correlation for amino acid-572 of TMC1. Kitajiri, S., Makishima, T., Friedman, T., Griffith, A. Clin. Genet. (2007)
- Methanol in dark clouds. Friberg, P., Madden, S.C., Hjalmarson, A., Irvine, W.M. Astronomy and astrophysics. (1988)
- Identification of the interstellar cyanomethyl radical (CH2CN) in the molecular clouds TMC-1 and Sagittarius B2. Irvine, W.M., Friberg, P., Hjalmarson, A., Ishikawa, S., Kaifu, N., Kawaguchi, K., Madden, S.C., Matthews, H.E., Ohishi, M., Saito, S., Suzuki, H., Thaddeus, P., Turner, B.E., Yamamoto, S., Ziurys, L.M. Astrophys. J. (1988)
- Detection of interstellar hydrogen sulfide in cold, dark clouds. Minh, Y.C., Irvine, W.M., Ziurys, L.M. Astrophys. J. (1989)
- Observations of some oxygen-containing and sulfur-containing organic molecules in cold dark clouds. Irvine, W.M., Friberg, P., Kaifu, N., Kawaguchi, K., Kitamura, Y., Matthews, H.E., Minh, Y., Saito, S., Ukita, N., Yamamoto, S. Astrophys. J. (1989)
- Tricarbon monoxide in TMC-1. Brown, R.D., Godfrey, P.D., Cragg, D.M., Rice, E.H., Irvine, W.M., Friberg, P., Suzuki, H., Ohishi, M., Kaifu, N., Morimoto, M. Astrophys. J. (1985)
- Four novel TMC1 (DFNB7/DFNB11) mutations in Turkish patients with congenital autosomal recessive nonsyndromic hearing loss. Kalay, E., Karaguzel, A., Caylan, R., Heister, A., Cremers, F.P., Cremers, C.W., Brunner, H.G., de Brouwer, A.P., Kremer, H. Hum. Mutat. (2005)
- Identification and mutation analysis of a cochlear-expressed, zinc finger protein gene at the DFNB7/11 and dn hearing-loss loci on human chromosome 9q and mouse chromosome 19. Scott, D.A., Greinwald, J.H., Marietta, J.R., Drury, S., Swiderski, R.E., Viñas, A., DeAngelis, M.M., Carmi, R., Ramesh, A., Kraft, M.L., Elbedour, K., Skworak, A.B., Friedman, R.A., Srikumari Srisailapathy, C.R., Verhoeven, K., Van Gamp, G., Lovett, M., Deininger, P.L., Batzer, M.A., Morton, C.C., Keats, B.J., Smith, R.J., Sheffield, V.C. Gene (1998)
- Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2. Scott, D.A., Drury, S., Sundstrom, R.A., Bishop, J., Swiderski, R.E., Carmi, R., Ramesh, A., Elbedour, K., Srikumari Srisailapathy, C.R., Keats, B.J., Sheffield, V.C., Smith, R.J. Gene (2000)