Gene Review:
Chek1 - checkpoint kinase 1
Mus musculus
Synonyms:
C85740, CHK1 checkpoint homolog, Checkpoint kinase-1, Chk1, Serine/threonine-protein kinase Chk1, ...
- Regulation of cellular and SV40 virus origins of replication by Chk1-dependent intrinsic and UVC radiation-induced checkpoints. Miao, H., Seiler, J.A., Burhans, W.C. J. Biol. Chem. (2003)
- Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. Brown, E.J., Baltimore, D. Genes Dev. (2003)
- Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice. Takai, H., Tominaga, K., Motoyama, N., Minamishima, Y.A., Nagahama, H., Tsukiyama, T., Ikeda, K., Nakayama, K., Nakanishi, M., Nakayama, K. Genes Dev. (2000)
- Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway. Weiss, R.S., Matsuoka, S., Elledge, S.J., Leder, P. Curr. Biol. (2002)
- Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure. Horton, J.K., Stefanick, D.F., Naron, J.M., Kedar, P.S., Wilson, S.H. J. Biol. Chem. (2005)
- Inhibition of the ATR/Chk1 pathway induces a p38-dependent S-phase delay in mouse embryonic stem cells. Jirmanova, L., Bulavin, D.V., Fornace, A.J. Cell Cycle (2005)
- Tissue-specific regulation of Chk1 expression by p53. Cheung, K.J., Li, G. Exp. Mol. Pathol. (2001)