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Gene Review

itr-1  -  Protein ITR-1

Caenorhabditis elegans

 
 
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Disease relevance of itr-1

  • An itr-1 gain-of-function mutation rescues infertility caused by egl-8 RNA interference, indicating that egl-8 and itr-1 function together as central components of the signaling events controlling sperm transfer [1].
 

High impact information on itr-1

 

Biological context of itr-1

 

Anatomical context of itr-1

 

Associations of itr-1 with chemical compounds

  • Thus tissue-specific expression of itr-1 variants is directed by three promoters and this results in adjacent cells in the same tissue containing different inositol trisphosphate receptor isoforms.Within pA, four short regions (pA-A to pA-D) of sequence conservation between C. elegans and C. briggsae were identified [5].

References

 
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