Gene Review:
Pnoc - prepronociceptin
Mus musculus
Synonyms:
N/OFQ, N23K, N23K/N27K, Npnc1, OFQ/N, ...
- Normal sensitivity to acute pain, but increased inflammatory hyperalgesia in mice lacking the nociceptin precursor polypeptide or the nociceptin receptor. Depner, U.B., Reinscheid, R.K., Takeshima, H., Brune, K., Zeilhofer, H.U. Eur. J. Neurosci. (2003)
- Regulation of the prepronociceptin gene and its effect on neuronal differentiation. Zaveri, N.T., Waleh, N., Toll, L. Gene (2006)
- Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors. Manabe, T., Noda, Y., Mamiya, T., Katagiri, H., Houtani, T., Nishi, M., Noda, T., Takahashi, T., Sugimoto, T., Nabeshima, T., Takeshima, H. Nature (1998)
- Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. Mollereau, C., Simons, M.J., Soularue, P., Liners, F., Vassart, G., Meunier, J.C., Parmentier, M. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Molecular cloning and characterization of a novel form of neuropeptide gene as a developmentally regulated molecule. Saito, Y., Maruyama, K., Kawano, H., Hagino-Yamagishi, K., Kawamura, K., Saido, T.C., Kawashima, S. J. Biol. Chem. (1996)
- Intracerebroventricular administration of nocistatin reduces inflammatory hyperalgesia in rats. Nakagawa, T., Kaneko, M., Inamura, S., Satoh, M. Neurosci. Lett. (1999)
- Staphylococcal enterotoxin B mutants (N23K and F44S): biological effects and vaccine potential in a mouse model. Woody, M.A., Krakauer, T., Stiles, B.G. Vaccine (1997)
- Intradermal nociceptin elicits itch-associated responses through leukotriene B(4) in mice. Andoh, T., Yageta, Y., Takeshima, H., Kuraishi, Y. J. Invest. Dermatol. (2004)
- Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system. Boom, A., Mollereau, C., Meunier, J.C., Vassart, G., Parmentier, M., Vanderhaeghen, J.J., Schiffmann, S.N. Neuroscience (1999)
- N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin. Saito, Y., Maruyama, K., Saido, T.C., Kawashima, S. Biochem. Biophys. Res. Commun. (1995)
- Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. Ring, R.H., Alder, J., Fennell, M., Kouranova, E., Black, I.B., Thakker-Varia, S. J. Neurobiol. (2006)