Gene Review:
NLRP7 - NLR family, pyrin domain containing 7
Homo sapiens
Synonyms:
CLR19.4, HYDM, NACHT, LRR and PYD domains-containing protein 7, NALP7, NOD12, ...
- Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans. Murdoch, S., Djuric, U., Mazhar, B., Seoud, M., Khan, R., Kuick, R., Bagga, R., Kircheisen, R., Ao, A., Ratti, B., Hanash, S., Rouleau, G.A., Slim, R. Nat. Genet. (2006)
- Oncogenic role of NALP7 in testicular seminomas. Okada, K., Hirota, E., Mizutani, Y., Fujioka, T., Shuin, T., Miki, T., Nakamura, Y., Katagiri, T. Cancer Sci. (2004)
- PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. Kinoshita, T., Wang, Y., Hasegawa, M., Imamura, R., Suda, T. J. Biol. Chem. (2005)
- Familial molar tissues due to mutations in the inflammatory gene, NALP7, have normal postzygotic DNA methylation. Djuric, U., El-Maarri, O., Lamb, B., Kuick, R., Seoud, M., Coullin, P., Oldenburg, J., Hanash, S., Slim, R. Hum. Genet. (2006)
- The genetics of hydatidiform moles: new lights on an ancient disease. Slim, R., Mehio, A. Clin. Genet. (2007)
- Overexpression of MDR1 using a retroviral vector differentially regulates genes involved in detoxification and apoptosis and confers radioprotection. Maier, P., Fleckenstein, K., Li, L., Laufs, S., Zeller, W.J., Baum, C., Fruehauf, S., Herskind, C., Wenz, F. Radiat. Res. (2006)