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Gene Review

Crisp2  -  cysteine-rich secretory protein 2

Mus musculus

Synonyms: CRISP-2, Cysteine-rich secretory protein 2, GAPDL5, Testis-specific protein TPX-1, Tpx-1, ...
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High impact information on Crisp2


Biological context of Crisp2


Anatomical context of Crisp2


Other interactions of Crisp2


Analytical, diagnostic and therapeutic context of Crisp2


  1. The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling. Gibbs, G.M., Scanlon, M.J., Swarbrick, J., Curtis, S., Gallant, E., Dulhunty, A.F., O'Bryan, M.K. J. Biol. Chem. (2006) [Pubmed]
  2. Expression of transcripts for cysteine-rich secretory proteins (CRISPs) in the murine lacrimal gland. Haendler, B., Toda, I., Sullivan, D.A., Schleuning, W.D. J. Cell. Physiol. (1999) [Pubmed]
  3. Evidence for the Involvement of Testicular Protein CRISP2 in Mouse Sperm-Egg Fusion. Busso, D., Goldweic, N.M., Hayashi, M., Kasahara, M., Cuasnicú, P.S. Biol. Reprod. (2007) [Pubmed]
  4. Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene. Kasahara, M., Gutknecht, J., Brew, K., Spurr, N., Goodfellow, P.N. Genomics (1989) [Pubmed]
  5. The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes. Mizuki, N., Sarapata, D.E., Garcia-Sanz, J.A., Kasahara, M. Mamm. Genome (1992) [Pubmed]
  6. Autoantigen 1 of the guinea pig sperm acrosome is the homologue of mouse Tpx-1 and human TPX1 and is a member of the cysteine-rich secretory protein (CRISP) family. Foster, J.A., Gerton, G.L. Mol. Reprod. Dev. (1996) [Pubmed]
  7. Differential androgen regulation of the murine genes for cysteine-rich secretory proteins (CRISP). Haendler, B., Habenicht, U.F., Schwidetzky, U., Schüttke, I., Schleuning, W.D. Eur. J. Biochem. (1997) [Pubmed]
  8. Identification of human candidate genes for male infertility by digital differential display. Olesen, C., Hansen, C., Bendsen, E., Byskov, A.G., Schwinger, E., Lopez-Pajares, I., Jensen, P.K., Kristoffersson, U., Schubert, R., Van Assche, E., Wahlstroem, J., Lespinasse, J., Tommerup, N. Mol. Hum. Reprod. (2001) [Pubmed]
  9. A testis-specific gene Tpx-1 maps between Pgk-2 and Mep-1 on mouse chromosome 17. Kasahara, M., Passmore, H.C., Klein, J. Immunogenetics (1989) [Pubmed]
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