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Gene Review

Urod  -  uroporphyrinogen decarboxylase

Rattus norvegicus

Synonyms: UPD, URO-D, Uroporphyrinogen decarboxylase
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  1. Hepatocarcinogenicity of hexachlorobenzene in rats and the sex difference in hepatic iron status and development of porphyria. Smith, A.G., Francis, J.E., Dinsdale, D., Manson, M.M., Cabral, J.R. Carcinogenesis (1985) [Pubmed]
  2. 2-Deoxy-D-galactose metabolism in ascites hepatoma cells results in phosphate trapping and glycolysis inhibition. Smith, D.F., Keppler, D.O. Eur. J. Biochem. (1977) [Pubmed]
  3. Uroporphyrinogen decarboxylase deficiency in experimental chronic hepatic porphyria. von Tiepermann, R., Koss, G., Doss, M. Hoppe-Seyler's Z. Physiol. Chem. (1980) [Pubmed]
  4. Isolation and identification of a cDNA clone coding for rat uroporphyrinogen decarboxylase. Romeo, P.H., Dubart, A., Grandchamp, B., de Verneuil, H., Rosa, J., Nordmann, Y., Goossens, M. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  5. Characterization of control and immobilized skeletal muscle: an overview from genetic engineering. St-Amand, J., Okamura, K., Matsumoto, K., Shimizu, S., Sogawa, Y. FASEB J. (2001) [Pubmed]
  6. Studies on porphyrin metabolism in the kidney. Effects of trace metals and glutathione on renal uroporphyrinogen decarboxylase. Woods, J.S., Eaton, D.L., Lukens, C.B. Mol. Pharmacol. (1984) [Pubmed]
  7. Hexachlorobenzene as a promoter of diethylnitrosamine-initiated hepatocarcinogenesis in rats and comparison with induction of porphyria. Stewart, F.P., Manson, M.M., Cabral, J.R., Smith, A.G. Carcinogenesis (1989) [Pubmed]
  8. Investigations of rat liver uroporphyrinogen decarboxylase. Comparisons of porphyrinogens I and III as substrates and the inhibition by porphyrins. Smith, A.G., Francis, J.E. Biochem. J. (1981) [Pubmed]
  9. The involvement of iron and lipid peroxidation in the pathogenesis of HCB induced porphyria. Alleman, M.A., Koster, J.F., Wilson, J.H., Edixhoven-Bosdijk, A., Slee, R.G., Kroos, M.J., von Eijk, H.G. Biochem. Pharmacol. (1985) [Pubmed]
  10. Activation of uroporphyrinogen decarboxylase by ferrous iron in porphyria cutanea tarda. Blekkenhorst, G.H., Eales, L., Pimstone, N.R. S. Afr. Med. J. (1979) [Pubmed]
  11. The decrease in uroporphyrinogen decarboxylase activity induced by ethanol predisposes rats to the development of porphyria and accelerates xenobiotic-triggered porphyria, regardless of hepatic damage. Ríos de Molina, M.C., Mazzetti, M.B., Galigniana, M., Aldonatti, C., Tomio, J.M., San Martín de Viale, L.C. Braz. J. Med. Biol. Res. (2002) [Pubmed]
  12. Decarboxylation of porphyrinogens by rat liver uroporphyrinogen decarboxylase. Smith, A.G., Francis, J.E. Biochem. J. (1979) [Pubmed]
  13. Time course of hexachlorobenzene-induced alterations of lipid metabolism and their relation to porphyria. Billi de Catabbi, S., Sterin-Speziale, N., Fernandez, M.C., Minutolo, C., Aldonatti, C., San Martín de Viale, L. Int. J. Biochem. Cell Biol. (1997) [Pubmed]
  14. Studies on the mechanism of uroporphyrinogen decarboxylase inhibition in hexachlorobenzene-induced porphyria in the female rat. Mylchreest, E., Charbonneau, M. Toxicol. Appl. Pharmacol. (1997) [Pubmed]
  15. Comparison between crab hepatopancreas and rat liver uroporphyrinogen decarboxylase. Chaufan, G., Corvi, M., Armesto, A., San Martín de Viale, L.C., Luquet, C., Ríos de Molina, M. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2002) [Pubmed]
  16. Increased inhibition of hepatic uroporphyrinogen decarboxylase by hexachlorobenzene in male rats given the oestrogenic drugs diethylstilboestrol and chlorotrianisene. Smith, A.G., Francis, J.E. Biochem. Pharmacol. (1981) [Pubmed]
  17. UDP-glucuronyltransferase in perfused rat liver and in microsomes. Effects of CCl4 injury. Bock, K.W., Huber, E., Schlote, W. Naunyn Schmiedebergs Arch. Pharmacol. (1977) [Pubmed]
  18. Effects of iron overload on bile secretion and hepatic porphyrin metabolism in ethinyl estradiol-treated rats. Cantoni, L., Di Padova, C., Rizzardini, M., Dal Fiume, D., Graziani, A., Rovagnati, P., Tritapepe, R. Toxicology (1986) [Pubmed]
  19. The effects of ethanol, estrogen, and hexachlorobenzene on the activities of hepatic delta-aminolevulinate synthetase, delta-aminolevulinate dehydratase, and uroporphyrinogen decarboxylase in male rats. Kondo, M., Shimizu, Y. Arch. Toxicol. (1986) [Pubmed]
  20. Inhibitory effect of tetrachloro-p-hydroquinone and other metabolites of hexachlorobenzene on hepatic uroporphyrinogen decarboxylase activity with reference to the role of glutathione. Koss, G., Losekam, M., Seidel, J., Steinbach, K., Koransky, W. Ann. N. Y. Acad. Sci. (1987) [Pubmed]
  21. The determination of uroporphyrinogen decarboxylase in tissues by high-performance liquid chromatography coupled to fluorescence detection. Cantoni, L., Ruggieri, R., Dal Fiume, D., Rizzardini, M. J. Chromatogr. (1982) [Pubmed]
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