The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Estinyl     (8S,9S,13S,14S,17S)-17- ethynyl-13-methyl-7...

Synonyms: Lynoral, Microfollin, Progynon C, Ethinyloestradiol, Microfollin Forte, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Lynoral


Psychiatry related information on Lynoral


High impact information on Lynoral


Chemical compound and disease context of Lynoral


Biological context of Lynoral


Anatomical context of Lynoral


Associations of Lynoral with other chemical compounds


Gene context of Lynoral


Analytical, diagnostic and therapeutic context of Lynoral


  1. Incidence of endometrial cancer in relation to the use of oral contraceptives. Weiss, N.S., Sayvetz, T.A. N. Engl. J. Med. (1980) [Pubmed]
  2. The effect of estrogen dose on postmenopausal bone loss. Horsman, A., Jones, M., Francis, R., Nordin, C. N. Engl. J. Med. (1983) [Pubmed]
  3. Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver. Bossard, R., Stieger, B., O'Neill, B., Fricker, G., Meier, P.J. J. Clin. Invest. (1993) [Pubmed]
  4. Synergism of estrogens and X-rays in mammary carcinogenesis in female ACI rats. Holtzman, S., Stone, J.P., Shellabarger, C.J. J. Natl. Cancer Inst. (1981) [Pubmed]
  5. Low-dose oral contraceptives: protective effect on ovarian cancer risk. Royar, J., Becher, H., Chang-Claude, J. Int. J. Cancer (2001) [Pubmed]
  6. Pentagastrin-induced release of free fatty acids in healthy volunteers and patients with panic disorder: effect of pretreatment with ethinyl estradiol. Morrow, J.D., McManus, K., Tait, G.R., Bellavance, F., Chrapko, W., Lara, N., Le Mellédo, J.M. Journal of psychiatry & neuroscience : JPN. (2003) [Pubmed]
  7. Effects of two low-dose oral contraceptives on serum lipids and lipoproteins: differential changes in high-density lipoprotein subclasses. Krauss, R.M., Roy, S., Mishell, D.R., Casagrande, J., Pike, M.C. Am. J. Obstet. Gynecol. (1983) [Pubmed]
  8. Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: a double-blind, placebo-controlled study. Strokosch, G.R., Friedman, A.J., Wu, S.C., Kamin, M. The Journal of adolescent health : official publication of the Society for Adolescent Medicine (2006) [Pubmed]
  9. Administration of 17alpha-ethinylestradiol during pregnancy elicits modifications of maternal behavior and emotional alteration of the offspring in the rat. Arabo, A., Lefebvre, M., Fermanel, M., Caston, J. Brain Res. Dev. Brain Res. (2005) [Pubmed]
  10. Ethinyl estradiol and norethindrone in the treatment of primary hyperparathyroidism in postmenopausal women. Selby, P.L., Peacock, M. N. Engl. J. Med. (1986) [Pubmed]
  11. Oral contraceptives, lanosterol, and platelet hyperactivity in rat. Ciavatti, M., Dumont, E., Benoit, C., Renaud, S. Science (1980) [Pubmed]
  12. Progestin-induced apoptosis in the Macaque ovarian epithelium: differential regulation of transforming growth factor-beta. Rodriguez, G.C., Nagarsheth, N.P., Lee, K.L., Bentley, R.C., Walmer, D.K., Cline, M., Whitaker, R.S., Isner, P., Berchuck, A., Dodge, R.K., Hughes, C.L. J. Natl. Cancer Inst. (2002) [Pubmed]
  13. Role of lipoprotein-X in the pathogenesis of cholestatic hypercholesterolemia. Uptake of lipoprotein-X and its effect on 3-hydroxy-3-methylglutaryl coenzyme A reductase and chylomicron remnant removal in human fibroblasts, lymphocytes, and in the rat. Walli, A.K., Seidel, D. J. Clin. Invest. (1984) [Pubmed]
  14. Cholesterol gallstone formation and prevention by chenodeoxycholic and ursodeoxycholic acids. A new hamster model. Pearlman, B.J., Bonorris, G.G., Phillips, M.J., Chung, A., Vimadalal, S., Marks, J.W., Schoenfield, L.J. Gastroenterology (1979) [Pubmed]
  15. S-adenosyl-L-methionine antagonizes ethynylestradiol-induced bile cholesterol supersaturation in humans without modifying the estrogen plasma kinetics. Di Padova, C., Tritapepe, R., Cammareri, G., Humpel, M., Stramentinoli, G. Gastroenterology (1982) [Pubmed]
  16. Sulfobromophthalein clearance tests before and after ethinyl estradiol administration, in women and men with familial history of intrahepatic cholestasis of pregnancy. Reyes, H., Ribalta, J., González, M.C., Segovia, N., Oberhauser, E. Gastroenterology (1981) [Pubmed]
  17. Induction of prostate carcinoma in situ at high incidence in F344 rats by a combination of 3,2'-dimethyl-4-aminobiphenyl and ethinyl estradiol. Shirai, T., Fukushima, S., Ikawa, E., Tagawa, Y., Ito, N. Cancer Res. (1986) [Pubmed]
  18. Zonal changes of hepatobiliary taurocholate transport in intrahepatic cholestasis induced by 17 alpha-ethinyl estradiol: a histoautoradiographic study in rats. Buscher, H.P., Meder, I., MacNelly, S., Gerok, W. Hepatology (1993) [Pubmed]
  19. Effects of ethinyl estradiol and phenobarbital on bile acid synthesis and biliary bile acid and cholesterol excretion. Davis, R.A., Kern, F. Gastroenterology (1976) [Pubmed]
  20. Decrease in endothelin-1 plasma levels during the menstrual cycle and after ethinylestradiol treatment. Merki-Feld, G.S., Keller, P.J. Ann. Intern. Med. (1999) [Pubmed]
  21. Modulation by S-adenosyl-L-methionine of hepatic Na+,K+-ATPase, membrane fluidity, and bile flow in rats with ethinyl estradiol-induced cholestasis. Boelsterli, U.A., Rakhit, G., Balazs, T. Hepatology (1983) [Pubmed]
  22. Ethinyl estradiol decreases acidification of rat liver endocytic vesicles. Van Dyke, R.W., Root, K.V. Hepatology (1993) [Pubmed]
  23. Relationship between bile flow and Na+, K+-adenosinetriphosphatase in liver plasma membranes enriched in bile canaliculi. Reichen, J., Paumgartner, G. J. Clin. Invest. (1977) [Pubmed]
  24. Effect of ethynodiol diacetate with ethinyl estradiol on the mammary glands of rhesus monkeys: a preliminary report. Drill, V.A., Golway, P.L. J. Natl. Cancer Inst. (1978) [Pubmed]
  25. Alterations in vesicle transport and cell polarity in rat hepatocytes subjected to mechanical or chemical cholestasis. Török, N.J., Larusso, E.M., McNiven, M.A. Gastroenterology (2001) [Pubmed]
  26. Expression of the bile salt export pump is maintained after chronic cholestasis in the rat. Lee, J.M., Trauner, M., Soroka, C.J., Stieger, B., Meier, P.J., Boyer, J.L. Gastroenterology (2000) [Pubmed]
  27. Population-based study of risk of venous thromboembolism associated with various oral contraceptives. Farmer, R.D., Lawrenson, R.A., Thompson, C.R., Kennedy, J.G., Hambleton, I.R. Lancet (1997) [Pubmed]
  28. Ethynylestradiol-induced impairment of bile secretion in the rat: protective effects of S-adenosyl-L-methionine and its implication in estrogen metabolism. Stramentinoli, G., Di Padova, C., Gualano, M., Rovagnati, P., Galli-Kienle, M. Gastroenterology (1981) [Pubmed]
  29. Lower esophageal sphincter pressure in women using sequential oral contraceptives. Van Thiel, D.H., Gavaler, J.S., Stremple, J. Gastroenterology (1976) [Pubmed]
  30. Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra. Timms, B.G., Howdeshell, K.L., Barton, L., Bradley, S., Richter, C.A., vom Saal, F.S. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  31. Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. Chen, S., Beaton, D., Nguyen, N., Senekeo-Effenberger, K., Brace-Sinnokrak, E., Argikar, U., Remmel, R.P., Trottier, J., Barbier, O., Ritter, J.K., Tukey, R.H. J. Biol. Chem. (2005) [Pubmed]
  32. Clinical pharmacokinetic profile of modafinil. Robertson, P., Hellriegel, E.T. Clinical pharmacokinetics. (2003) [Pubmed]
  33. Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3. Chu, X.Y., Huskey, S.E., Braun, M.P., Sarkadi, B., Evans, D.C., Evers, R. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  34. Effects of ethinyloestradiol on plasma levels of pituitary gonadotrophins, testicular steroids and sex hormone binding globulin in normal men. Van Look, P.F., Frölich, M. Clin. Endocrinol. (Oxf) (1981) [Pubmed]
  35. The involvement of CYP3A4 and CYP2C9 in the metabolism of 17 alpha-ethinylestradiol. Wang, B., Sanchez, R.I., Franklin, R.B., Evans, D.C., Huskey, S.E. Drug Metab. Dispos. (2004) [Pubmed]
  36. Structure-function correlation of tight junctional impairment after intrahepatic and extrahepatic cholestasis in rat liver. Rahner, C., Stieger, B., Landmann, L. Gastroenterology (1996) [Pubmed]
  37. Hepatocellular carcinoma after treatment with cyproterone acetate combined with ethinyloestradiol. Rüdiger, T., Beckmann, J., Queisser, W. Lancet (1995) [Pubmed]
  38. The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Trauner, M., Arrese, M., Soroka, C.J., Ananthanarayanan, M., Koeppel, T.A., Schlosser, S.F., Suchy, F.J., Keppler, D., Boyer, J.L. Gastroenterology (1997) [Pubmed]
  39. Assessment of estrogenic recruitment before chemotherapy in advanced breast cancer: a double-blind randomized study. European Organization for Research and Treatment of Cancer Breast Cancer Cooperative Group. Paridaens, R., Heuson, J.C., Julien, J.P., Veyret, C., Van Zyl, J., Klijn, J.G., Sylvester, R., Mignolet, F. J. Clin. Oncol. (1993) [Pubmed]
  40. Effects of oral contraceptive and estrogen administration on plasma calcitonin in pre- and postmenopausal women. Hurley, D.L., Tiegs, R.D., Barta, J., Laakso, K., Heath, H. J. Bone Miner. Res. (1989) [Pubmed]
WikiGenes - Universities