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Disease relevance of Hepatopancreas


High impact information on Hepatopancreas


Chemical compound and disease context of Hepatopancreas


Biological context of Hepatopancreas


Anatomical context of Hepatopancreas


Associations of Hepatopancreas with chemical compounds

  • When blue crabs are exposed to cadmium in their diet, the metal accumulates in the hepatopancreas [23].
  • 6. Pyruvate kinase activity in the supernatant of a hepatopancreas homogenate was completely activated by fructose 1,6-bisphosphate, suggesting that the binding of this ligand to the purified pyruvate kinase was impaired [24].
  • 1. The mechanisms that control the oxidative phase of the pentose phosphate cycle in mussel hepatopancreas were investigated [25].
  • The cysteine proteinase accounted for 80% of the proteolytic activity in the lumen of the hepatopancreas [26].
  • alpha-L-Fucosidase, prepared in highly purified form (Mr 70 000-74 000) from Octopus hepatopancreas, was able to hydrolyse a fucose-containing ganglioside, namely Fuc-GM1 (II3NeuAc,IV2Fuc-GgOse4-Cer) [27].

Gene context of Hepatopancreas


Analytical, diagnostic and therapeutic context of Hepatopancreas


  1. Accumulation and translation of ferritin heavy chain transcripts following anoxia exposure in a marine invertebrate. Larade, K., Storey, K.B. J. Exp. Biol. (2004) [Pubmed]
  2. Cyanobacteria and prawn farming in northern New South Wales, Australia--a case study on cyanobacteria diversity and hepatotoxin bioaccumulation. Kankaanpää, H.T., Holliday, J., Schröder, H., Goddard, T.J., von Fister, R., Carmichael, W.W. Toxicol. Appl. Pharmacol. (2005) [Pubmed]
  3. Acute toxicity of cadmium and copper in hepatopancreas cells from the Roman snail (Helix pomatia). Manzl, C., Krumschnabel, G., Schwarzbaum, P.J., Dallinger, R. Comp. Biochem. Physiol. C Toxicol. Pharmacol. (2004) [Pubmed]
  4. Isolation of a cadmium-releasing bacterium and characterization of its novel protease. Ren, S., Tomita, F., Yokota, A., Asano, K. Biosci. Biotechnol. Biochem. (2004) [Pubmed]
  5. Crustacean intestinal detergent promotes sterol solubilization. Lester, R., Carey, M.C., Little, J.M., Cooperatein, L.A., Dowd, S.R. Science (1975) [Pubmed]
  6. Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi. Ji, X., Azumi, K., Sasaki, M., Nonaka, M. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  7. Transcriptional regulation of limulus factor C: repression of an NFkappaB motif modulates its responsiveness to bacterial lipopolysaccharide. Wang, L., Ho, B., Ding, J.L. J. Biol. Chem. (2003) [Pubmed]
  8. 2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN)- and N-acetylneuraminic acid-cleaving sialidase (KDN-sialidase) and KDN-cleaving hydrolase (KDNase) from the hepatopancreas of oyster, Crassostrea virginica. Pavlova, N.V., Yuziuk, J.A., Nakagawa, H., Kiso, M., Li, S.C., Li, Y.T. J. Biol. Chem. (1999) [Pubmed]
  9. D-Mannitol oxidation in the land snail, Helix aspersa. Vorhaben, J.E., Scott, J.F., Campbell, J.W. J. Biol. Chem. (1980) [Pubmed]
  10. Physiological roles of free D- and L-alanine in the crayfish Procambarus clarkii with special reference to osmotic and anoxic stress responses. Fujimori, T., Abe, H. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. (2002) [Pubmed]
  11. Protein kinase and phosphatase responses to anoxia in crayfish, Orconectes virilis: purification and characterization of cAMP-dependent protein kinase. Cowan, K.J., Storey, K.B. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2001) [Pubmed]
  12. Hepatopancreas gluconeogenesis during anoxia and post-anoxia recovery in Chasmagnathus granulata crabs maintained on high-protein or carbohydrate-rich diets. Oliveira, G.T., Eichler, P., Rossi, I.C., Da Silva, R.S. J. Exp. Zoolog. Part A Comp. Exp. Biol. (2004) [Pubmed]
  13. Molecular cloning of the complement regulatory factor I isotypes from the common carp (Cyprinus carpio). Nakao, M., Hisamatsu, S., Nakahara, M., Kato, Y., Smith, S.L., Yano, T. Immunogenetics (2003) [Pubmed]
  14. Characterization of vitellogenin in the shrimp Metapenaeus ensis: Expression studies and hormonal regulation of MeVg1 transcription in vitro. Tiu, S.H., Hui, J.H., He, J.G., Tobe, S.S., Chan, S.M. Mol. Reprod. Dev. (2006) [Pubmed]
  15. Hypometabolism, antioxidant defenses and free radical metabolism in the pulmonate land snail Helix aspersa. Ramos-Vasconcelos, G.R., Hermes-Lima, M. J. Exp. Biol. (2003) [Pubmed]
  16. Exposure to air, but not seawater, increases the glutamine content and the glutamine synthetase activity in the marsh clam Polymesoda expansa. Hiong, K.C., Peh, W.Y., Loong, A.M., Wong, W.P., Chew, S.F., Ip, Y.K. J. Exp. Biol. (2004) [Pubmed]
  17. Sublethal effect of naphthalene on lipid peroxidation and antioxidant status in the edible marine crab Scylla serrata. Vijayavel, K., Gomathi, R.D., Durgabhavani, K., Balasubramanian, M.P. Mar. Pollut. Bull. (2004) [Pubmed]
  18. Cytochrome P-450-dependent oxidation of progesterone, testosterone, and ecdysone in the spiny lobster, Panulirus argus. James, M.O., Shiverick, K.T. Arch. Biochem. Biophys. (1984) [Pubmed]
  19. Evolution of novel functions: cryptocyanin helps build new exoskeleton in Cancer magister. Terwilliger, N.B., Ryan, M.C., Towle, D. J. Exp. Biol. (2005) [Pubmed]
  20. Respiratory and calcium transport properties of spiny lobster hepatopancreas mitochondria. Tsokos, J., Kreisberg, R., Michaels, A., Komm, B., Linton, J. Arch. Biochem. Biophys. (1983) [Pubmed]
  21. Metabolic profiles of penaied shrimp: dietary lipids and ovarian maturation. Middleditch, B.S., Missler, S.R., Hines, H.B., McVey, J.P., Brown, A., Ward, D.G., Lawrence, A.L. J. Chromatogr. (1980) [Pubmed]
  22. Molecular cloning of Limulus alpha 2-macroglobulin. Iwaki, D., Kawabata, S., Miura, Y., Kato, A., Armstrong, P.B., Quigley, J.P., Nielsen, K.L., Dolmer, K., Sottrup-Jensen, L., Iwanaga, S. Eur. J. Biochem. (1996) [Pubmed]
  23. Primary structure and tissue-specific expression of blue crab (Callinectes sapidus) metallothionein isoforms. Brouwer, M., Enghild, J., Hoexum-Brouwer, T., Thogersen, I., Truncali, A. Biochem. J. (1995) [Pubmed]
  24. A steady-state kinetic analysis of the fructose 1,6-bisphosphate-activated pyruvate kinase from Carcinus maenas hepatopancreas. Giles, I.G., Poat, P.C. Biochem. J. (1980) [Pubmed]
  25. Regulation of the oxidative phase of the pentose phosphate cycle in mussels. Rodriguez-Segade, S., Freire, M., Carrion, A. Biochem. J. (1978) [Pubmed]
  26. Purification and characterization of a digestive cysteine proteinase from the American lobster (Homarus americanus). Laycock, M.V., Hirama, T., Hasnain, S., Watson, D., Storer, A.C. Biochem. J. (1989) [Pubmed]
  27. Alpha-fucosidase-ganglioside interactions. Action of alpha-L-fucosidase from the hepatopancreas of Octopus vulgaris on a fucose-containing ganglioside (Fuc-GM1). Masserini, M., Giuliani, A., Venerando, B., Fiorilli, A., D'Aniello, A., Tettamanti, G. Biochem. J. (1985) [Pubmed]
  28. The complement component C5 of the common carp (Cyprinus carpio): cDNA cloning of two distinct isotypes that differ in a functional site. Kato, Y., Nakao, M., Mutsuro, J., Zarkadis, I.K., Yano, T. Immunogenetics (2003) [Pubmed]
  29. Antioxidant responses to benzo[a]pyrene and Aroclor 1254 exposure in the green-lipped mussel, Perna viridis. Cheung, C.C., Siu, W.H., Richardson, B.J., De Luca-Abbott, S.B., Lam, P.K. Environ. Pollut. (2004) [Pubmed]
  30. Molecular characterization of D-amino acid oxidase from common carp Cyprinus carpio and its induction with exogenous free D-alanine. Sarower, M.G., Okada, S., Abe, H. Arch. Biochem. Biophys. (2003) [Pubmed]
  31. Purification and characterization of grass carp mitochondrial aldehyde dehydrogenase. Fong, W., Choy, K. Chem. Biol. Interact. (2001) [Pubmed]
  32. Seasonal modulation of free radical metabolism in estivating land snails Helix aspersa. Ramos-Vasconcelos, G.R., Cardoso, L.A., Hermes-Lima, M. Comp. Biochem. Physiol. C Toxicol. Pharmacol. (2005) [Pubmed]
  33. Cadmium-binding proteins of three marine molluscs and characterization of two cadmium-binding glycoproteins from the hepatopancreas of a whelk, Buccinum tenuissimum. Dohi, Y., Kosaka, K., Ohba, K., Yoneyama, Y. Environ. Health Perspect. (1986) [Pubmed]
  34. Frameshift mutations induced by the acridine mustard ICR-191 in embryos and in the adult gill and hepatopancreas of rpsL transgenic zebrafish. Nakamura, T., Amanuma, K., Aoki, Y. Mutat. Res. (2005) [Pubmed]
  35. The purification and characterization of glutathione S-transferase from the hepatopancreas of the blue crab, Callinectes sapidus. Keeran, W.S., Lee, R.F. Arch. Biochem. Biophys. (1987) [Pubmed]
  36. Isolation and characterization of octopus hepatopancreatic glutathione S-transferase. Comparison of digestive gland enzyme with lens S-crystallin. Tang, S.S., Lin, C.C., Chang, G.G. J. Protein Chem. (1994) [Pubmed]
  37. Heavy metals in the terrestrial isopod Porcellio scaber Latreille. II. Subcellular fractionation of metal-accumulating lysosomes from hepatopancreas. Dallinger, R., Prosi, F. Cell Biol. Toxicol. (1988) [Pubmed]
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