The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

AC1L96S8     [(3R,4R,5S,6R)-3-acetamido- 4,5-dihydroxy-6...

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of UDP-N-acetyl-D-glucosamine


Psychiatry related information on UDP-N-acetyl-D-glucosamine


High impact information on UDP-N-acetyl-D-glucosamine


Chemical compound and disease context of UDP-N-acetyl-D-glucosamine


Biological context of UDP-N-acetyl-D-glucosamine


Anatomical context of UDP-N-acetyl-D-glucosamine


Associations of UDP-N-acetyl-D-glucosamine with other chemical compounds


Gene context of UDP-N-acetyl-D-glucosamine


Analytical, diagnostic and therapeutic context of UDP-N-acetyl-D-glucosamine


  1. The UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase gene is mutated in recessive hereditary inclusion body myopathy. Eisenberg, I., Avidan, N., Potikha, T., Hochner, H., Chen, M., Olender, T., Barash, M., Shemesh, M., Sadeh, M., Grabov-Nardini, G., Shmilevich, I., Friedmann, A., Karpati, G., Bradley, W.G., Baumbach, L., Lancet, D., Asher, E.B., Beckmann, J.S., Argov, Z., Mitrani-Rosenbaum, S. Nat. Genet. (2001) [Pubmed]
  2. Transport of protein between cytoplasmic membranes of fused cells: correspondence to processes reconstituted in a cell-free system. Rothman, J.E., Urbani, L.J., Brands, R. J. Cell Biol. (1984) [Pubmed]
  3. Mannose 6-phosphate-independent targeting of lysosomal enzymes in I-cell disease B lymphoblasts. Glickman, J.N., Kornfeld, S. J. Cell Biol. (1993) [Pubmed]
  4. Mutations in the human UDP-N-acetylglucosamine 2-epimerase gene define the disease sialuria and the allosteric site of the enzyme. Seppala, R., Lehto, V.P., Gahl, W.A. Am. J. Hum. Genet. (1999) [Pubmed]
  5. Shortened hydroxyacyl chains on lipid A of Escherichia coli cells expressing a foreign UDP-N-acetylglucosamine O-acyltransferase. Odegaard, T.J., Kaltashov, I.A., Cotter, R.J., Steeghs, L., van der Ley, P., Khan, S., Maskell, D.J., Raetz, C.R. J. Biol. Chem. (1997) [Pubmed]
  6. Differential labelling of UDP-N-acetylglucosamine in Huntington's-chorea fibroblasts. Hung, W.Y., Tourian, A. Biochem. J. (1981) [Pubmed]
  7. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Wang, J., Liu, R., Hawkins, M., Barzilai, N., Rossetti, L. Nature (1998) [Pubmed]
  8. A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase. Raetz, C.R., Roderick, S.L. Science (1995) [Pubmed]
  9. Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture. Peneff, C., Ferrari, P., Charrier, V., Taburet, Y., Monnier, C., Zamboni, V., Winter, J., Harnois, M., Fassy, F., Bourne, Y. EMBO J. (2001) [Pubmed]
  10. Independent and simultaneous translocation of two substrates by a nucleotide sugar transporter. Caffaro, C.E., Hirschberg, C.B., Berninsone, P.M. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  11. Mediators of galactose sensitivity in UDP-galactose 4'-epimerase-impaired mammalian cells. Schulz, J.M., Ross, K.L., Malmstrom, K., Krieger, M., Fridovich-Keil, J.L. J. Biol. Chem. (2005) [Pubmed]
  12. Incorporation of N-acetyl-D-glucosamine from UDP-N-acetyl-D-glucosamine by isolated membranes of Bacillus subtilis. Identification of undecaprenyl poly(N-acetylglucosaminyl pyrophosphate). Bettinger, G.E., Chatterjee, A.N., Young, F.E. J. Biol. Chem. (1977) [Pubmed]
  13. Lateral transfers of serine hydroxymethyltransferase (glyA) and UDP-N-acetylglucosamine enolpyruvyl transferase (murA) genes from free-living Actinobacteria to the parasitic chlamydiae. Griffiths, E., Gupta, R.S. J. Mol. Evol. (2006) [Pubmed]
  14. Vi antigen biosynthesis in Salmonella typhi: characterization of UDP-N-acetylglucosamine C-6 dehydrogenase (TviB) and UDP-N-acetylglucosaminuronic acid C-4 epimerase (TviC). Zhang, H., Zhou, Y., Bao, H., Liu, H.W. Biochemistry (2006) [Pubmed]
  15. Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site. Thoden, J.B., Wohlers, T.M., Fridovich-Keil, J.L., Holden, H.M. J. Biol. Chem. (2001) [Pubmed]
  16. Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aeruginosa: substrate specificity in udp-hexose 4-epimerases. Ishiyama, N., Creuzenet, C., Lam, J.S., Berghuis, A.M. J. Biol. Chem. (2004) [Pubmed]
  17. Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity. Donthi, R.V., Ye, G., Wu, C., McClain, D.A., Lange, A.J., Epstein, P.N. J. Biol. Chem. (2004) [Pubmed]
  18. Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc. Kneass, Z.T., Marchase, R.B. J. Biol. Chem. (2004) [Pubmed]
  19. Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis. Pedersen, L.C., Dong, J., Taniguchi, F., Kitagawa, H., Krahn, J.M., Pedersen, L.G., Sugahara, K., Negishi, M. J. Biol. Chem. (2003) [Pubmed]
  20. Vectorial synthesis of a polysaccharide by isolated plasma membranes. Cabib, E., Bowers, B., Roberts, R.L. Proc. Natl. Acad. Sci. U.S.A. (1983) [Pubmed]
  21. Mammalian Golgi apparatus UDP-N-acetylglucosamine transporter: molecular cloning by phenotypic correction of a yeast mutant. Guillen, E., Abeijon, C., Hirschberg, C.B. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  22. A Gne knockout mouse expressing human V572L mutation develops features similar to distal myopathy with rimmed vacuoles or hereditary inclusion body myopathy. Malicdan, M.C., Noguchi, S., Nonaka, I., Hayashi, Y.K., Nishino, I. Hum. Mol. Genet. (2007) [Pubmed]
  23. Evidence that UDP-glucuronyltransferase in liver microsomes at 37 degrees C is in a gel phase lipid environment. Hochman, Y., Zakim, D. J. Biol. Chem. (1983) [Pubmed]
  24. A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA). Eschenburg, S., Priestman, M.A., Abdul-Latif, F.A., Delachaume, C., Fassy, F., Schönbrunn, E. J. Biol. Chem. (2005) [Pubmed]
  25. Increased expression of UDP-galactose transporter messenger RNA in human colon cancer tissues and its implication in synthesis of Thomsen-Friedenreich antigen and sialyl Lewis A/X determinants. Kumamoto, K., Goto, Y., Sekikawa, K., Takenoshita, S., Ishida, N., Kawakita, M., Kannagi, R. Cancer Res. (2001) [Pubmed]
  26. Molecular cloning and identification of N-acyl-D-glucosamine 2-epimerase from porcine kidney as a renin-binding protein. Maru, I., Ohta, Y., Murata, K., Tsukada, Y. J. Biol. Chem. (1996) [Pubmed]
  27. Analysis of the streptococcal hyaluronic acid synthase complex using the photoaffinity probe 5-azido-UDP-glucuronic acid. van de Rijn, I., Drake, R.R. J. Biol. Chem. (1992) [Pubmed]
  28. Co-purification and characterization of UDP-glucose 4-epimerase and UDP-N-acetylglucosamine 4-epimerase from porcine submaxillary glands. Piller, F., Hanlon, M.H., Hill, R.L. J. Biol. Chem. (1983) [Pubmed]
  29. Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle. Patti, M.E., Virkamäki, A., Landaker, E.J., Kahn, C.R., Yki-Järvinen, H. Diabetes (1999) [Pubmed]
  30. Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis. Mio, T., Yamada-Okabe, T., Arisawa, M., Yamada-Okabe, H. J. Biol. Chem. (1999) [Pubmed]
  31. Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation. Gao, X.D., Tachikawa, H., Sato, T., Jigami, Y., Dean, N. J. Biol. Chem. (2005) [Pubmed]
  32. Complex asparagine-linked oligosaccharides in Mgat1-null embryos. Campbell, R.M., Metzler, M., Granovsky, M., Dennis, J.W., Marth, J.D. Glycobiology (1995) [Pubmed]
  33. Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family. Ishida, N., Kuba, T., Aoki, K., Miyatake, S., Kawakita, M., Sanai, Y. Genomics (2005) [Pubmed]
  34. The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein. Tan, J., D'Agostaro, A.F., Bendiak, B., Reck, F., Sarkar, M., Squire, J.A., Leong, P., Schachter, H. Eur. J. Biochem. (1995) [Pubmed]
  35. Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans: UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I. Sarkar, M., Hull, E., Nishikawa, Y., Simpson, R.J., Moritz, R.L., Dunn, R., Schachter, H. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  36. Characterization of the N-acetylglucosaminyltransferase activity involved in the biosynthesis of the Staphylococcus epidermidis polysaccharide intercellular adhesin. Gerke, C., Kraft, A., Süssmuth, R., Schweitzer, O., Götz, F. J. Biol. Chem. (1998) [Pubmed]
  37. Hexosamines regulate leptin production in human subcutaneous adipocytes. Considine, R.V., Cooksey, R.C., Williams, L.B., Fawcett, R.L., Zhang, P., Ambrosius, W.T., Whitfield, R.M., Jones, R., Inman, M., Huse, J., McClain, D.A. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  38. Thermodynamic characterization of ligand-induced conformational changes in UDP-N-acetylglucosamine enolpyruvyl transferase. Samland, A.K., Jelesarov, I., Kuhn, R., Amrhein, N., Macheroux, P. Biochemistry (2001) [Pubmed]
WikiGenes - Universities