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Gene Review

salr  -  spalt-related

Drosophila melanogaster

Synonyms: 32F, CG4881, Cf3, Dmel\CG4881, Sal-r, ...
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Anatomical context of salr


Other interactions of salr

  • Here, we present the isolation and characterization of novel spalt/spalt-related alleles, which analysis indicates that these genes cannot substitute for each other in the developmental processes studied [8].
  • We find that dachshund and spalt/spalt-related are essential for proper joint formation between particular antennal segments [9].


  1. The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Sakaki-Yumoto, M., Kobayashi, C., Sato, A., Fujimura, S., Matsumoto, Y., Takasato, M., Kodama, T., Aburatani, H., Asashima, M., Yoshida, N., Nishinakamura, R. Development (2006) [Pubmed]
  2. Two-step process for photoreceptor formation in Drosophila. Mollereau, B., Dominguez, M., Webel, R., Colley, N.J., Keung, B., de Celis, J.F., Desplan, C. Nature (2001) [Pubmed]
  3. Drosophila spalt/spalt-related mutants exhibit Townes-Brocks' syndrome phenotypes. Dong, P.D., Todi, S.V., Eberl, D.F., Boekhoff-Falk, G. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  4. Spalt transcription factors are required for R3/R4 specification and establishment of planar cell polarity in the Drosophila eye. Domingos, P.M., Mlodzik, M., Mendes, C.S., Brown, S., Steller, H., Mollereau, B. Development (2004) [Pubmed]
  5. Regulation of the spalt/spalt-related gene complex and its function during sensory organ development in the Drosophila thorax. de Celis, J.F., Barrio, R., Kafatos, F.C. Development (1999) [Pubmed]
  6. Regulation, function and potential origin of the Drosophila gene spalt adjacent, which encodes a secreted protein expressed in the early embryo. Reuter, D., Kühnlein, R.P., Frommer, G., Barrio, R., Kafatos, F.C., Jäckle, H., Schuh, R. Chromosoma (1996) [Pubmed]
  7. Mutations in spalt cause a severe but reversible neurodegenerative phenotype in the embryonic central nervous system of Drosophila melanogaster. Cantera, R., Lüer, K., Rusten, T.E., Barrio, R., Kafatos, F.C., Technau, G.M. Development (2002) [Pubmed]
  8. Identification of regulatory regions driving the expression of the Drosophila spalt complex at different developmental stages. Barrio, R., de Celis, J.F., Bolshakov, S., Kafatos, F.C. Dev. Biol. (1999) [Pubmed]
  9. Distal-less and homothorax regulate multiple targets to pattern the Drosophila antenna. Dong, P.D., Dicks, J.S., Panganiban, G. Development (2002) [Pubmed]
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