Gene Review:
Cdk9 - Cyclin-dependent kinase 9
Drosophila melanogaster
Synonyms:
CDK9, CG5179, Dmel\CG5179, P-TEF, P-TEFb, ...
- P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Mancebo, H.S., Lee, G., Flygare, J., Tomassini, J., Luu, P., Zhu, Y., Peng, J., Blau, C., Hazuda, D., Price, D., Flores, O. Genes Dev. (1997)
- P-TEFb kinase recruitment and function at heat shock loci. Lis, J.T., Mason, P., Peng, J., Price, D.H., Werner, J. Genes Dev. (2000)
- Identification of multiple cyclin subunits of human P-TEFb. Peng, J., Zhu, Y., Milton, J.T., Price, D.H. Genes Dev. (1998)
- Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes. Ni, Z., Schwartz, B.E., Werner, J., Suarez, J.R., Lis, J.T. Mol. Cell (2004)
- Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment. Eissenberg, J.C., Shilatifard, A., Dorokhov, N., Michener, D.E. Mol. Genet. Genomics (2007)
- Identification of a cyclin subunit required for the function of Drosophila P-TEFb. Peng, J., Marshall, N.F., Price, D.H. J. Biol. Chem. (1998)
- Control of formation of two distinct classes of RNA polymerase II elongation complexes. Marshall, N.F., Price, D.H. Mol. Cell. Biol. (1992)
- Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo. Chao, S.H., Price, D.H. J. Biol. Chem. (2001)