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ADORA1  -  adenosine A1 receptor

Canis lupus familiaris

 
 
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Disease relevance of ADORA1

 

High impact information on ADORA1

 

Biological context of ADORA1

 

Associations of ADORA1 with chemical compounds

 

Analytical, diagnostic and therapeutic context of ADORA1

  • The effects of intravenous infusion of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine), a novel adenosine A1-receptor antagonist, on urine volume, urinary excretion of electrolytes and renal hemodynamics were examined in anesthetized dogs [6].

References

  1. Glibenclamide antagonizes adenosine A1 receptor-mediated cardioprotection in stunned canine myocardium. Yao, Z., Gross, G.J. Circulation (1993) [Pubmed]
  2. Effect of the selective adenosine A1-receptor antagonist KW-3902 on lipopolysaccharide-induced reductions in urine volume and renal blood flow in anesthetized dogs. Yao, K., Ina, Y., Nagashima, K., Ohno, T., Karasawa, A. Jpn. J. Pharmacol. (2000) [Pubmed]
  3. Ischemic preconditioning protects post-ischemic renal function in anesthetized dogs: role of adenosine and adenine nucleotides. Li, F.Z., Kimura, S., Nishiyama, A., Rahman, M., Zhang, G.X., Abe, Y. Acta Pharmacol. Sin. (2005) [Pubmed]
  4. Effect of N-0861, a selective adenosine A1 receptor antagonist, on pharmacologic stress imaging with adenosine. Glover, D.K., Ruiz, M., Sansoy, V., Barrett, R.J., Beller, G.A. J. Nucl. Med. (1995) [Pubmed]
  5. Are negative chronotropic and inotropic responses to adenosine differentiated at the receptor or postreceptor levels in isolated dog hearts? Oguchi, T., Furukawa, Y., Sawaki, S., Kasama, M., Chiba, S. J. Pharmacol. Exp. Ther. (1995) [Pubmed]
  6. Diuretic effects of KW-3902, a novel adenosine A1-receptor antagonist, in anesthetized dogs. Yamagata, T., Kobayashi, T., Kusaka, H., Karasawa, A. Biol. Pharm. Bull. (1994) [Pubmed]
  7. Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor. IJzerman, A.P., Van Galen, P.J., Jacobson, K.A. Drug design and discovery. (1992) [Pubmed]
  8. Effects of KW-3902, a selective and potent adenosine A1 receptor antagonist, on renal hemodynamics and urine formation in anesthetized dogs. Aki, Y., Tomohiro, A., Nishiyama, A., Kiyomoto, K., Kimura, S., Abe, Y. Pharmacology (1997) [Pubmed]
  9. Effects of OG-VI, a nucleoside/nucleotide mixture, on stunned myocardium in dogs: is the adenosine A1 receptor involved? Kano, S., Satoh, K., Hoshi, K., Ichihara, K. Coron. Artery Dis. (1998) [Pubmed]
  10. No participation of adenosine A1 receptor in acute nephrotoxicity by 4-pentenoic acid administration in dogs. Miura, K., Okumura, M., Yamanaka, S., Kim, S., Iwao, H. Jpn. J. Pharmacol. (1999) [Pubmed]
  11. Diuretic effects of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine), a novel adenosine A1 receptor antagonist, in conscious dogs. Kobayashi, T., Mizumoto, H., Karasawa, A. Biol. Pharm. Bull. (1993) [Pubmed]
  12. Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs. Auchampach, J.A., Gross, G.J. Am. J. Physiol. (1993) [Pubmed]
 
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