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MeSH Review

Myocardial Stunning

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Disease relevance of Myocardial Stunning


High impact information on Myocardial Stunning


Chemical compound and disease context of Myocardial Stunning


Biological context of Myocardial Stunning


Anatomical context of Myocardial Stunning


Gene context of Myocardial Stunning


Analytical, diagnostic and therapeutic context of Myocardial Stunning


  1. Protection of the stunned myocardium. Selective nucleoside transport blocker administered after 20 minutes of ischemia augments recovery of ventricular function. Abd-Elfattah, A.S., Ding, M., Dyke, C.M., Wechsler, A.S. Circulation (1993) [Pubmed]
  2. Prostaglandin redirection by thromboxane synthetase inhibition. Attenuation of myocardial stunning in canine heart. Farber, N.E., Gross, G.J. Circulation (1990) [Pubmed]
  3. Direct evidence that the hydroxyl radical plays a pathogenetic role in myocardial "stunning" in the conscious dog and demonstration that stunning can be markedly attenuated without subsequent adverse effects. Sekili, S., McCay, P.B., Li, X.Y., Zughaib, M., Sun, J.Z., Tang, L., Thornby, J.I., Bolli, R. Circ. Res. (1993) [Pubmed]
  4. Nitric oxide-mediated effects of interleukin-6 on [Ca2+]i and cell contraction in cultured chick ventricular myocytes. Kinugawa, K., Takahashi, T., Kohmoto, O., Yao, A., Aoyagi, T., Momomura, S., Hirata, Y., Serizawa, T. Circ. Res. (1994) [Pubmed]
  5. The calcium sensitizer levosimendan improves the function of stunned myocardium after percutaneous transluminal coronary angioplasty in acute myocardial ischemia. Sonntag, S., Sundberg, S., Lehtonen, L.A., Kleber, F.X. J. Am. Coll. Cardiol. (2004) [Pubmed]
  6. Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone. Bolli, R., Patel, B.S., Jeroudi, M.O., Lai, E.K., McCay, P.B. J. Clin. Invest. (1988) [Pubmed]
  7. Gene therapy with extracellular superoxide dismutase attenuates myocardial stunning in conscious rabbits. Li, Q., Bolli, R., Qiu, Y., Tang, X.L., Murphree, S.S., French, B.A. Circulation (1998) [Pubmed]
  8. Randomized, double-blind crossover study to investigate the effects of amlodipine and isosorbide mononitrate on the time course and severity of exercise-induced myocardial stunning. Rinaldi, C.A., Linka, A.Z., Masani, N.D., Avery, P.G., Jones, E., Saunders, H., Hall, R.J. Circulation (1998) [Pubmed]
  9. Dobutamine echocardiography and quantitative rest-redistribution 201Tl tomography in myocardial hibernation. Relation of contractile reserve to 201Tl uptake and comparative prediction of recovery of function. Qureshi, U., Nagueh, S.F., Afridi, I., Vaduganathan, P., Blaustein, A., Verani, M.S., Winters, W.L., Zoghbi, W.A. Circulation (1997) [Pubmed]
  10. Myocardial blood flow, glucose uptake, and recruitment of inotropic reserve in chronic left ventricular ischemic dysfunction. Implications for the pathophysiology of chronic myocardial hibernation. Gerber, B.L., Vanoverschelde, J.L., Bol, A., Michel, C., Labar, D., Wijns, W., Melin, J.A. Circulation (1996) [Pubmed]
  11. Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects. Zughaib, M.E., Abd-Elfattah, A.S., Jeroudi, M.O., Sun, J.Z., Sekili, S., Tang, X.L., Bolli, R. Circulation (1993) [Pubmed]
  12. Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. Bolli, R., Jeroudi, M.O., Patel, B.S., DuBose, C.M., Lai, E.K., Roberts, R., McCay, P.B. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  13. Attenuation of myocardial stunning by the ACE inhibitor ramiprilat through a signal cascade of bradykinin and prostaglandins but not nitric oxide. Ehring, T., Baumgart, D., Krajcar, M., Hümmelgen, M., Kompa, S., Heusch, G. Circulation (1994) [Pubmed]
  14. Heart rate reduction during exercise-induced myocardial ischaemia and stunning. Monnet, X., Colin, P., Ghaleh, B., Hittinger, L., Giudicelli, J.F., Berdeaux, A. Eur. Heart J. (2004) [Pubmed]
  15. Increased activity of the sarcoplasmic reticular calcium pump in porcine stunned myocardium. Lamers, J.M., Duncker, D.J., Bezstarosti, K., McFalls, E.O., Sassen, L.M., Verdouw, P.D. Cardiovasc. Res. (1993) [Pubmed]
  16. Coronary reactivity in the porcine heart after short lasting myocardial ischaemia: effects of duration of ischaemia and myocardial stunning. Kirkeböen, K.A., Aksnes, G., Ilebekk, A. Cardiovasc. Res. (1990) [Pubmed]
  17. Kinetics of a putative hypoxic tissue marker, technetium-99m-nitroimidazole (BMS181321), in normoxic, hypoxic, ischemic and stunned myocardium. Kusuoka, H., Hashimoto, K., Fukuchi, K., Nishimura, T. J. Nucl. Med. (1994) [Pubmed]
  18. Perfusion-contraction mismatch during inotropic stimulation in hibernating myocardium. Sambuceti, G., Giorgetti, A., Corsiglia, L., Marini, C., Schneider-Eicke, J., Brunelli, C., Marzullo, P., L'Abbate, A., Capponnetto, S., Parodi, O. J. Nucl. Med. (1998) [Pubmed]
  19. Development of short-term myocardial hibernation. Its limitation by the severity of ischemia and inotropic stimulation. Schulz, R., Rose, J., Martin, C., Brodde, O.E., Heusch, G. Circulation (1993) [Pubmed]
  20. Endothelium dependent vasodilatation following brief ischaemia and reperfusion in anaesthetised swine. McFalls, E.O., Duncker, D.J., Krams, R., Ward, H., Gornick, C., Verdouw, P.D. Cardiovasc. Res. (1991) [Pubmed]
  21. In vivo evidence that EMD 57033 restores myocardial responsiveness to intracoronary Ca(2+) in stunned myocardium. de Zeeuw, S., Trines, S.A., Krams, R., Duncker, D.J., Verdouw, P.D. Eur. J. Pharmacol. (2000) [Pubmed]
  22. Protection of regional mechanics and mitochondrial oxidative phosphorylation by amlodipine in transiently ischemic myocardium. Dunlap, E.D., Matlib, M.A., Millard, R.W. Am. J. Cardiol. (1989) [Pubmed]
  23. Bypass conduit vessel wall biology substantially influences downstream myocardial contractile response to injury from ischemia and reperfusion. Robinson, B.L., Morita, T., Fujita, K., Chow, M., Schaff, H.V., Morris, J.J. J. Thorac. Cardiovasc. Surg. (1996) [Pubmed]
  24. Endothelin does not contribute to the attenuation in myocardial function and blood flow after repetitive ischemia in the rat heart. Tiefenbacher, C.P., Tweddell, A., Batkai, S., Zimmermann, R., Tillmanns, H., Kübler, W. J. Vasc. Res. (1997) [Pubmed]
  25. Role of troponin I proteolysis in the pathogenesis of stunned myocardium. Gao, W.D., Atar, D., Liu, Y., Perez, N.G., Murphy, A.M., Marban, E. Circ. Res. (1997) [Pubmed]
  26. MnSOD antisense treatment and exercise-induced protection against arrhythmias. Hamilton, K.L., Quindry, J.C., French, J.P., Staib, J., Hughes, J., Mehta, J.L., Powers, S.K. Free Radic. Biol. Med. (2004) [Pubmed]
  27. Accelerated recovery of postischemic stunned myocardium after induced expression of myocardial heat-shock protein (HSP70). Robinson, B.L., Morita, T., Toft, D.O., Morris, J.J. J. Thorac. Cardiovasc. Surg. (1995) [Pubmed]
  28. Effects of BIBR-277, an angiotensin II type 1 receptor antagonist, on stunned myocardium in dogs. Izumi, H., Nakai, T., Kano, S., Hoshi, K., Ichihara, K. Coron. Artery Dis. (1996) [Pubmed]
  29. Activation of adenosine receptors before ischemia enhances tolerance against myocardial stunning in the rabbit heart. Ogawa, T., Miura, T., Shimamoto, K., Iimura, O. J. Am. Coll. Cardiol. (1996) [Pubmed]
  30. Left ventricular dysfunction following transient ischaemia induced by transluminal coronary angioplasty. Beneficial effects of calcium antagonists against post-ischaemic myocardial stunning. Sheiban, I., Tonni, S., Benussi, P., Marini, A., Trevi, G.P. Eur. Heart J. (1993) [Pubmed]
  31. Recovery of perfusion, glucose utilization and fatty acid utilization in stunned myocardium. Tsubokawa, A., Lee, J.D., Shimizu, H., Nakano, A., Uzui, H., Takeuchi, M., Tsuchida, T., Yonekura, Y., Ishii, Y., Ueda, T. J. Nucl. Med. (1997) [Pubmed]
  32. The effects of thoracic epidural anesthesia on functional recovery from myocardial stunning in propofol-anesthetized dogs. Rolf, N., Meissner, A., Van Aken, H., Weber, T.P., Hammel, D., Möllhoff, T. Anesth. Analg. (1997) [Pubmed]
  33. Adenosine triphosphate-dependent potassium channel modulation and cardioplegia-induced protection of human atrial muscle in an in vitro model of myocardial stunning. Monti, F., Iwashiro, K., Picard, S., Criniti, A., La Francesca, S., Ruvolo, G., Papalia, U., Campa, P.P., Marino, B., Puddu, P.E. J. Thorac. Cardiovasc. Surg. (2000) [Pubmed]
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