Gene Review:
PNPO - pyridoxamine 5'-phosphate oxidase
Homo sapiens
Synonyms:
HEL-S-302, PDXPO, Pyridoxamine-phosphate oxidase, Pyridoxine-5'-phosphate oxidase
- Absence of pyridoxine-5'-phosphate oxidase (PNPO) activity in neoplastic cells: isolation, characterization, and expression of PNPO cDNA. Ngo, E.O., LePage, G.R., Thanassi, J.W., Meisler, N., Nutter, L.M. Biochemistry (1998)
- Genomic organization, tissue distribution and deletion mutation of human pyridoxine 5'-phosphate oxidase. Kang, J.H., Hong, M.L., Kim, D.W., Park, J., Kang, T.C., Won, M.H., Baek, N.I., Moon, B.J., Choi, S.Y., Kwon, O.S. Eur. J. Biochem. (2004)
- The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6 angstroms resolution. Biswal, B.K., Au, K., Cherney, M.M., Garen, C., James, M.N. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. (2006)
- Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase. Mills, P.B., Surtees, R.A., Champion, M.P., Beesley, C.E., Dalton, N., Scambler, P.J., Heales, S.J., Briddon, A., Scheimberg, I., Hoffmann, G.F., Zschocke, J., Clayton, P.T. Hum. Mol. Genet. (2005)
- Pyridoxine-dependent seizures: new genetic and biochemical clues to help with diagnosis and treatment. Gospe, S.M. Curr. Opin. Neurol. (2006)
- Vigabatrin inhibits pyridoxine-5'-phosphate oxidase, not pyridoxal kinase in the hippocampus of seizure prone gerbils. An, S.J., Park, S.K., Hwang, I.K., Choi, S.Y., Kwon, O.S., Won, M.H., Kang, T.C. Neurochem. Int. (2004)
- Chronological changes in pyridoxine-5'-phosphate oxidase immunoreactivity in the seizure-sensitive gerbil hippocampus. Kang, T.C., Park, S.K., Hwang, I.K., An, S.J., Bahn, J.H., Kim, A.Y., Choi, S.Y., Kwon, O.S., Baek, N.I., Lee, H.Y., Won, M.H. J. Neurosci. Res. (2002)
- Structure of Escherichia coli pyridoxine 5'-phosphate oxidase in a tetragonal crystal form: insights into the mechanistic pathway of the enzyme. Safo, M.K., Musayev, F.N., Schirch, V. Acta Crystallogr. D Biol. Crystallogr. (2005)
- A simple fluorimetric assay for pyridoxamine phosphate oxidase in erythrocyte haemolysates: effects of riboflavin supplementation and of glucose 6-phosphate dehydrogenase deficiency. Bates, C.J., Powers, H.J. Human nutrition. Clinical nutrition. (1985)
- Age-dependent changes of pyridoxal phosphate synthesizing enzymes immunoreactivities and activities in the gerbil hippocampal CA1 region. Hwang, I.K., Kim, D.W., Jung, J.Y., Yoo, K.Y., Cho, J.H., Kwon, O.S., Kang, T.C., Choi, S.Y., Kim, Y.S., Won, M.H. Mech. Ageing Dev. (2005)