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Gene Review

IFNK  -  interferon, kappa

Homo sapiens

Synonyms: IFN-kappa, IFNT1, INFE1, Interferon kappa, UNQ6124/PRO20084
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Disease relevance of IFNK


High impact information on IFNK


Biological context of IFNK


Anatomical context of IFNK


Analytical, diagnostic and therapeutic context of IFNK

  • However, in contrast to IFN-alpha2b transcriptional signaling and antiviral activity, IFN-kappa activity was not detectable in conditioned cell culture medium [3].


  1. Regulatory effect of IFN-kappa, a novel type I IFN, on cytokine production by cells of the innate immune system. Nardelli, B., Zaritskaya, L., Semenuk, M., Cho, Y.H., LaFleur, D.W., Shah, D., Ullrich, S., Girolomoni, G., Albanesi, C., Moore, P.A. J. Immunol. (2002) [Pubmed]
  2. Analysis of IFN-kappa expression in pathologic skin conditions: downregulation in psoriasis and atopic dermatitis. Scarponi, C., Nardelli, B., Lafleur, D.W., Moore, P.A., Madonna, S., De Pità, O., Girolomoni, G., Albanesi, C. J. Interferon Cytokine Res. (2006) [Pubmed]
  3. Antiviral activity of transiently expressed IFN-kappa is cell-associated. Buontempo, P.J., Jubin, R.G., Buontempo, C.A., Wagner, N.E., Reyes, G.R., Baroudy, B.M. J. Interferon Cytokine Res. (2006) [Pubmed]
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