Gene Review:
chico - CG5686 gene product from transcript CG5686-RB
Drosophila melanogaster
Synonyms:
BcDNA.GH11263, BcDNA:GH11263, CG5686, CHICO, Chico, ...
- Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary. Richard, D.S., Rybczynski, R., Wilson, T.G., Wang, Y., Wayne, M.L., Zhou, Y., Partridge, L., Harshman, L.G. J. Insect Physiol. (2005)
- Insulin regulation of heart function in aging fruit flies. Wessells, R.J., Fitzgerald, E., Cypser, J.R., Tatar, M., Bodmer, R. Nat. Genet. (2004)
- Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Böhni, R., Riesgo-Escovar, J., Oldham, S., Brogiolo, W., Stocker, H., Andruss, B.F., Beckingham, K., Hafen, E. Cell (1999)
- Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Clancy, D.J., Gems, D., Harshman, L.G., Oldham, S., Stocker, H., Hafen, E., Leevers, S.J., Partridge, L. Science (2001)
- Distinct genetic influences on locomotor senescence in Drosophila revealed by a series of metrical analyses. Martin, I., Grotewiel, M.S. Exp. Gerontol. (2006)
- Superoxide dismutase activities in long-lived Drosophila melanogaster females: chico (1) genotypes and dietary dilution. Kabil, H., Partridge, L., Harshman, L.G. Biogerontology (2007)
- The demography of slow aging in male and female Drosophila mutant for the insulin-receptor substrate homologue chico. Tu, M.P., Epstein, D., Tatar, M. Aging Cell (2002)
- Characterization of Drosophila insulin receptor substrate. Poltilove, R.M., Jacobs, A.R., Haft, C.R., Xu, P., Taylor, S.I. J. Biol. Chem. (2000)
- Mutations in insulin signaling pathway alter juvenile hormone synthesis in Drosophila melanogaster. Tu, M.P., Yin, C.M., Tatar, M. Gen. Comp. Endocrinol. (2005)
- Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Goberdhan, D.C., Paricio, N., Goodman, E.C., Mlodzik, M., Wilson, C. Genes Dev. (1999)
- Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Clemens, J.C., Worby, C.A., Simonson-Leff, N., Muda, M., Maehama, T., Hemmings, B.A., Dixon, J.E. Proc. Natl. Acad. Sci. U.S.A. (2000)
- A second maternally expressed Drosophila gene encodes a putative RNA helicase of the "DEAD box" family. de Valoir, T., Tucker, M.A., Belikoff, E.J., Camp, L.A., Bolduc, C., Beckingham, K. Proc. Natl. Acad. Sci. U.S.A. (1991)