Gene Review:
Pi3K92E - CG4141 gene product from transcript CG4141-RB
Drosophila melanogaster
Synonyms:
CG4141, DP110, Dmel\CG4141, Dmp110, Dp110, ...
- Phosphatidylinositol 3-kinase and Akt nonautonomously promote perineurial glial growth in Drosophila peripheral nerves. Lavery, W., Hall, V., Yager, J.C., Rottgers, A., Wells, M.C., Stern, M. J. Neurosci. (2007)
- The cytohesin Steppke is essential for insulin signalling in Drosophila. Fuss, B., Becker, T., Zinke, I., Hoch, M. Nature (2006)
- Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth. Hietakangas, V., Cohen, S.M. Genes Dev. (2007)
- Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein. Feldmann, P., Eicher, E.N., Leevers, S.J., Hafen, E., Hughes, D.A. Mol. Cell. Biol. (1999)
- TRB3 is a PI 3-kinase dependent indicator for nutrient starvation. Schwarzer, R., Dames, S., Tondera, D., Klippel, A., Kaufmann, J. Cell. Signal. (2006)
- A nutrient sensor mechanism controls Drosophila growth. Colombani, J., Raisin, S., Pantalacci, S., Radimerski, T., Montagne, J., Léopold, P. Cell (2003)
- Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing. Prober, D.A., Edgar, B.A. Genes Dev. (2002)
- Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Goberdhan, D.C., Paricio, N., Goodman, E.C., Mlodzik, M., Wilson, C. Genes Dev. (1999)
- Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Weinkove, D., Neufeld, T.P., Twardzik, T., Waterfield, M.D., Leevers, S.J. Curr. Biol. (1999)
- Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B. Lizcano, J.M., Alrubaie, S., Kieloch, A., Deak, M., Leevers, S.J., Alessi, D.R. Biochem. J. (2003)
- Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain. Virbasius, J.V., Guilherme, A., Czech, M.P. J. Biol. Chem. (1996)
- FOXO-independent suppression of programmed cell death by the PI3K/Akt signaling pathway in Drosophila. Liu, Y., Lehmann, M. Dev. Genes Evol. (2006)
- Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins. Aoki, M., Jiang, H., Vogt, P.K. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Functional folding of a cytoplasmic single-chain variable fragment and its use as elutable protein purification tag. Elis, W., Reth, M., Huber, M. Immunol. Lett. (2004)
- Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component. Myster, S.H., Cavallo, R., Anderson, C.T., Fox, D.T., Peifer, M. J. Cell Biol. (2003)
- Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells. Kim, S.E., Cho, J.Y., Kim, K.S., Lee, S.J., Lee, K.H., Choi, K.Y. Cell. Signal. (2004)
- Input from Ras is required for maximal PI(3)K signalling in Drosophila. Orme, M.H., Alrubaie, S., Bradley, G.L., Walker, C.D., Leevers, S.J. Nat. Cell Biol. (2006)
- Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Yang, Y., Gehrke, S., Haque, M.E., Imai, Y., Kosek, J., Yang, L., Beal, M.F., Nishimura, I., Wakamatsu, K., Ito, S., Takahashi, R., Lu, B. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Identification and cDNA cloning of a novel mammalian C2 domain-containing phosphoinositide 3-kinase, HsC2-PI3K. Brown, R.A., Ho, L.K., Weber-Hall, S.J., Shipley, J.M., Fry, M.J. Biochem. Biophys. Res. Commun. (1997)
- An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Brogiolo, W., Stocker, H., Ikeya, T., Rintelen, F., Fernandez, R., Hafen, E. Curr. Biol. (2001)
- Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Caldwell, P.E., Walkiewicz, M., Stern, M. Curr. Biol. (2005)
- Effects of 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one on synaptic vesicle cycling at the frog neuromuscular junction. Rizzoli, S.O., Betz, W.J. J. Neurosci. (2002)