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Gene Review

SPDS1  -  spermidine synthase 1

Arabidopsis thaliana

Synonyms: F5O8.38, F5O8_38
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Disease relevance of SPDS1


High impact information on SPDS1


Biological context of SPDS1


Associations of SPDS1 with chemical compounds


Other interactions of SPDS1

  • Here we report the characterization of the other three genes, designated SPDS1, SPDS2 and SPDS3 [4].


  1. Overexpression of spermidine synthase enhances tolerance to multiple environmental stresses and up-regulates the expression of various stress-regulated genes in transgenic Arabidopsis thaliana. Kasukabe, Y., He, L., Nada, K., Misawa, S., Ihara, I., Tachibana, S. Plant Cell Physiol. (2004) [Pubmed]
  2. A polyamine metabolon involving aminopropyl transferase complexes in Arabidopsis. Panicot, M., Minguet, E.G., Ferrando, A., Alcázar, R., Blázquez, M.A., Carbonell, J., Altabella, T., Koncz, C., Tiburcio, A.F. Plant Cell (2002) [Pubmed]
  3. Spermidine synthase genes are essential for survival of Arabidopsis. Imai, A., Matsuyama, T., Hanzawa, Y., Akiyama, T., Tamaoki, M., Saji, H., Shirano, Y., Kato, T., Hayashi, H., Shibata, D., Tabata, S., Komeda, Y., Takahashi, T. Plant Physiol. (2004) [Pubmed]
  4. Characterization of the spermidine synthase-related gene family in Arabidopsis thaliana. Hanzawa, Y., Imai, A., Michael, A.J., Komeda, Y., Takahashi, T. FEBS Lett. (2002) [Pubmed]
  5. Structural and mechanistic insights into the action of Plasmodium falciparum spermidine synthase. Burger, P.B., Birkholtz, L.M., Joubert, F., Haider, N., Walter, R.D., Louw, A.I. Bioorg. Med. Chem. (2007) [Pubmed]
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