Gene Review:
RAD17 - Rad17p
Saccharomyces cerevisiae S288c
Synonyms:
DNA damage checkpoint control protein RAD17, DNA repair exonuclease RAD17, YOR368W
- Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Lee, S.E., Moore, J.K., Holmes, A., Umezu, K., Kolodner, R.D., Haber, J.E. Cell (1998)
- A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Lydall, D., Nikolsky, Y., Bishop, D.K., Weinert, T. Nature (1996)
- Checkpoint activation regulates mutagenic translesion synthesis. Kai, M., Wang, T.S. Genes Dev. (2003)
- Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis. Freire, R., Murguía, J.R., Tarsounas, M., Lowndes, N.F., Moens, P.B., Jackson, S.P. Genes Dev. (1998)
- The mitotic DNA damage checkpoint proteins Rad17 and Rad24 are required for repair of double-strand breaks during meiosis in yeast. Shinohara, M., Sakai, K., Ogawa, T., Shinohara, A. Genetics (2003)
- RAD9, RAD17, and RAD24 are required for S phase regulation in Saccharomyces cerevisiae in response to DNA damage. Paulovich, A.G., Margulies, R.U., Garvik, B.M., Hartwell, L.H. Genetics (1997)
- Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway. Kondo, T., Matsumoto, K., Sugimoto, K. Mol. Cell. Biol. (1999)
- Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. Longhese, M.P., Paciotti, V., Neecke, H., Lucchini, G. Genetics (2000)
- G2/M checkpoint genes of Saccharomyces cerevisiae: further evidence for roles in DNA replication and/or repair. Lydall, D., Weinert, T. Mol. Gen. Genet. (1997)
- The Rad17 homologue of Arabidopsis is involved in the regulation of DNA damage repair and homologous recombination. Heitzeberg, F., Chen, I.P., Hartung, F., Orel, N., Angelis, K.J., Puchta, H. Plant J. (2004)
- A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Giannattasio, M., Sommariva, E., Vercillo, R., Lippi-Boncambi, F., Liberi, G., Foiani, M., Plevani, P., Muzi-Falconi, M. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p. Paciotti, V., Lucchini, G., Plevani, P., Longhese, M.P. EMBO J. (1998)
- Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Weinert, T.A., Kiser, G.L., Hartwell, L.H. Genes Dev. (1994)
- NDT80 and the meiotic recombination checkpoint regulate expression of middle sporulation-specific genes in Saccharomyces cerevisiae. Hepworth, S.R., Friesen, H., Segall, J. Mol. Cell. Biol. (1998)
- Cloning and characterization of RAD17, a gene controlling cell cycle responses to DNA damage in Saccharomyces cerevisiae. Siede, W., Nusspaumer, G., Portillo, V., Rodriguez, R., Friedberg, E.C. Nucleic Acids Res. (1996)